BODG_HUMAN - dbPTM
BODG_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID BODG_HUMAN
UniProt AC O75936
Protein Name Gamma-butyrobetaine dioxygenase
Gene Name BBOX1
Organism Homo sapiens (Human).
Sequence Length 387
Subcellular Localization Cytoplasm.
Protein Description Catalyzes the formation of L-carnitine from gamma-butyrobetaine..
Protein Sequence MACTIQKAEALDGAHLMQILWYDEEESLYPAVWLRDNCPCSDCYLDSAKARKLLVEALDVNIGIKGLIFDRKKVYITWPDEHYSEFQADWLKKRCFSKQARAKLQRELFFPECQYWGSELQLPTLDFEDVLRYDEHAYKWLSTLKKVGIVRLTGASDKPGEVSKLGKRMGFLYLTFYGHTWQVQDKIDANNVAYTTGKLSFHTDYPALHHPPGVQLLHCIKQTVTGGDSEIVDGFNVCQKLKKNNPQAFQILSSTFVDFTDIGVDYCDFSVQSKHKIIELDDKGQVVRINFNNATRDTIFDVPVERVQPFYAALKEFVDLMNSKESKFTFKMNPGDVITFDNWRLLHGRRSYEAGTEISRHLEGAYADWDVVMSRLRILRQRVENGN
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
156PhosphorylationIVRLTGASDKPGEVS
EEEEECCCCCCCCHH		47.73-
295PhosphorylationRINFNNATRDTIFDV
EEECCCCCCCCCEEE		31.0728857561
298PhosphorylationFNNATRDTIFDVPVE
CCCCCCCCCEEEEHH		21.9128857561
315AcetylationQPFYAALKEFVDLMN
HHHHHHHHHHHHHHC		44.367822129
323PhosphorylationEFVDLMNSKESKFTF
HHHHHHCCCCCCEEE		24.6822468782
326PhosphorylationDLMNSKESKFTFKMN
HHHCCCCCCEEEECC		36.4822468782
329PhosphorylationNSKESKFTFKMNPGD
CCCCCCEEEECCCCC		26.5322468782
351PhosphorylationRLLHGRRSYEAGTEI
EEECCCCHHHCCCHH		26.4328857561
352PhosphorylationLLHGRRSYEAGTEIS
EECCCCHHHCCCHHH		14.1628857561
359PhosphorylationYEAGTEISRHLEGAY
HHCCCHHHHHHCCCC		13.8624425749
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of BODG_HUMAN !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of BODG_HUMAN !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of BODG_HUMAN !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
BODG_HUMANBBOX1physical
25416956
SHOT1_HUMANKIAA1598physical
25416956
RTF2_HUMANRTFDC1physical
26186194
AZI2_HUMANAZI2physical
26186194
TBK1_HUMANTBK1physical
26186194
TXLNA_HUMANTXLNAphysical
26186194
ITPR3_HUMANITPR3physical
26186194
CASP2_HUMANCASP2physical
26186194
SSFA2_HUMANSSFA2physical
26186194
IF1AX_HUMANEIF1AXphysical
26186194
ITPR2_HUMANITPR2physical
26186194
CACO2_HUMANCALCOCO2physical
26186194
TANK_HUMANTANKphysical
26186194
RPC6_HUMANPOLR3Fphysical
26186194
PCBP3_HUMANPCBP3physical
26186194
AZI2_HUMANAZI2physical
28514442
CASP2_HUMANCASP2physical
28514442
TBK1_HUMANTBK1physical
28514442
TANK_HUMANTANKphysical
28514442
SSFA2_HUMANSSFA2physical
28514442
RPC6_HUMANPOLR3Fphysical
28514442
RTF2_HUMANRTFDC1physical
28514442
PCBP3_HUMANPCBP3physical
28514442
ITPR2_HUMANITPR2physical
28514442
ITPR3_HUMANITPR3physical
28514442
TXLNA_HUMANTXLNAphysical
28514442
CPIN1_HUMANCIAPIN1physical
28514442
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of BODG_HUMAN

loading...

Related Literatures of Post-Translational Modification

TOP
© 2024 Institute of Bioinformatics and Systems Biology, NYCU | Designed by : BiOmics Laboratory