ARN1_YEAST - dbPTM
ARN1_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID ARN1_YEAST
UniProt AC P38731
Protein Name Siderophore iron transporter ARN1
Gene Name ARN1
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 627
Subcellular Localization Cell membrane
Multi-pass membrane protein . Endosome membrane
Multi-pass membrane protein .
Protein Description Involved in the transport of siderophore ferrichrome and so has a role in iron homeostasis..
Protein Sequence MESVHSRDPVKEEKKHVFMGMEHELNPETHNDSNSDSYGLPQLSEKYNALRQNRSLIIQQTEIIGSAYNKWYLQAILLLSAFICGYGYGLDGNIRYIYTGYATSSYSEHSLLSTINVINAVVSAASQIIYARLSDVFGRLYLFISAVILYVVGTIIQSQAYDVQRYAAGAIFYNAGYVGVILILLIILSDFSSLKWRLLYQFVPTWPFIINTWIAGNITSRANPVVNWSWDVGMWAFIFPLSCVPIVLCMLHMQWRARKTPEWHALKGQKSYYQEHGFIKILKQLFWMLDVVGVLLMGCSLGCILVPLTLAGGVKTTWNDSRLIGPFVLGFVLIPILWIWEYRFARDPILPYRLVKDRAVWSSMGISFLIDFIYYMAADYLYTVMIVAVNESVKSATRIATLSSFVSTVASPFFALLVTRCTRLKPFIMFGCALWMVAMGLLYHFRGGSQSHSGIIGALCVWGVGTTLFTYPVTVSVQSAVSHENMATVTALNYTLYRIGSAVGSAVSGAIWTQTLYKQILKRMGDVALATTAYESPYTFIETYTWGTPQRNALMNAYKYVQRLETIVALVFCVPLIAFSLCLRDPKLTDTVAVEYIEDGEYVDTKDNDPILDWFEKLPSKFTFKRE
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
3Phosphorylation-----MESVHSRDPV
-----CCCCCCCCCC		24.6728889911
6Phosphorylation--MESVHSRDPVKEE
--CCCCCCCCCCCHH		35.9028889911
29PhosphorylationEHELNPETHNDSNSD
CEECCCCCCCCCCCC		27.5119779198
35PhosphorylationETHNDSNSDSYGLPQ
CCCCCCCCCCCCHHH		31.7019779198
44PhosphorylationSYGLPQLSEKYNALR
CCCHHHHHHHHHHHH		27.1319779198
363PhosphorylationKDRAVWSSMGISFLI
CCHHHHHHHCHHHHH		12.8119779198
538PhosphorylationTTAYESPYTFIETYT
ECCCCCCCEEEEECC		24.4619779198
548PhosphorylationIETYTWGTPQRNALM
EEECCCCCHHHHHHH		14.0719779198
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources
-KUbiquitinationE3 ubiquitin ligaseRSP5P39940
PMID:22199232
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of ARN1_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of ARN1_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
GGA2_YEASTGGA2genetic
19574226
PMA1_YEASTPMA1physical
19574226
YCP7_YEASTYCR007Cgenetic
20093466
VMS1_YEASTVMS1genetic
20093466
DYL1_YEASTDYN2genetic
20093466
DSD1_YEASTDSD1genetic
20093466
MSC1_YEASTMSC1genetic
20093466
NGL2_YEASTNGL2genetic
20093466
YP109_YEASTYPL109Cgenetic
20093466
PRPD_YEASTPDH1genetic
20093466
BRO1_YEASTBRO1genetic
20526336
FAB1_YEASTFAB1genetic
20526336
AIM4_YEASTAIM4genetic
27708008
YCP7_YEASTYCR007Cgenetic
27708008
DYL1_YEASTDYN2genetic
27708008
DSD1_YEASTDSD1genetic
27708008
CBT1_YEASTCBT1genetic
27708008
MSC1_YEASTMSC1genetic
27708008
ALDH6_YEASTALD6genetic
27708008
PRPD_YEASTPDH1genetic
27708008
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of ARN1_YEAST

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Related Literatures of Post-Translational Modification

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