dbPTM

ANR11_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	ANR11_HUMAN
UniProt AC	Q6UB99
Protein Name	Ankyrin repeat domain-containing protein 11
Gene Name	ANKRD11
Organism	Homo sapiens (Human).
Sequence Length	2663
Subcellular Localization	Nucleus . Localizes to chromatin during prometaphase.
Protein Description	Chromatin regulator which modulates histone acetylation and gene expression in neural precursor cells (By similarity). May recruit histone deacetylases (HDACs) to the p160 coactivators/nuclear receptor complex to inhibit ligand-dependent transactivation. [PubMed: 15184363 Has a role in proliferation and development of cortical neural precursors]
Protein Sequence	MPKGGCPKAPQQEELPLSSDMVEKQTGKKDKDKVSLTKTPKLERGDGGKEVRERASKRKLPFTAGANGEQKDSDTEKQGPERKRIKKEPVTRKAGLLFGMGLSGIRAGYPLSERQQVALLMQMTAEESANSPVDTTPKHPSQSTVCQKGTPNSASKTKDKVNKRNERGETRLHRAAIRGDARRIKELISEGADVNVKDFAGWTALHEACNRGYYDVAKQLLAAGAEVNTKGLDDDTPLHDAANNGHYKVVKLLLRYGGNPQQSNRKGETPLKVANSPTMVNLLLGKGTYTSSEESSTESSEEEDAPSFAPSSSVDGNNTDSEFEKGLKHKAKNPEPQKATAPVKDEYEFDEDDEQDRVPPVDDKHLLKKDYRKETKSNSFISIPKMEVKSYTKNNTIAPKKASHRILSDTSDEEDASVTVGTGEKLRLSAHTILPGSKTREPSNAKQQKEKNKVKKKRKKETKGREVRFGKRSDKFCSSESESESSESGEDDRDSLGSSGCLKGSPLVLKDPSLFSSLSASSTSSHGSSAAQKQNPSHTDQHTKHWRTDNWKTISSPAWSEVSSLSDSTRTRLTSESDYSSEGSSVESLKPVRKRQEHRKRASLSEKKSPFLSSAEGAVPKLDKEGKVVKKHKTKHKHKNKEKGQCSISQELKLKSFTYEYEDSKQKSDKAILLENDLSTENKLKVLKHDRDHFKKEEKLSKMKLEEKEWLFKDEKSLKRIKDTNKDISRSFREEKDRSNKAEKERSLKEKSPKEEKLRLYKEERKKKSKDRPSKLEKKNDLKEDKISKEKEKIFKEDKEKLKKEKVYREDSAFDEYCNKNQFLENEDTKFSLSDDQRDRWFSDLSDSSFDFKGEDSWDSPVTDYRDMKSDSVAKLILETVKEDSKERRRDSRAREKRDYREPFFRKKDRDYLDKNSEKRKEQTEKHKSVPGYLSEKDKKRRESAEAGRDRKDALESCKERRDGRAKPEEAHREELKECGCESGFKDKSDGDFGKGLEPWERHHPAREKEKKDGPDKERKEKTKPERYKEKSSDKDKSEKSILEKCQKDKEFDKCFKEKKDTKEKHKDTHGKDKERKASLDQGKEKKEKAFPGIISEDFSEKKDDKKGKEKSWYIADIFTDESEDDRDSCMGSGFKMGEASDLPRTDGLQEKEEGREAYASDRHRKSSDKQHPERQKDKEPRDRRKDRGAADAGRDKKEKVFEKHKEKKDKESTEKYKDRKDRASVDSTQDKKNKQKLPEKAEKKHAAEDKAKSKHKEKSDKEHSKERKSSRSADAEKSLLEKLEEEALHEYREDSNDKISEVSSDSFTDRGQEPGLTAFLEVSFTEPPGDDKPRESACLPEKLKEKERHRHSSSSSKKSHDRERAKKEKAEKKEKGEDYKEGGSRKDSGQYEKDFLEADAYGVSYNMKADIEDELDKTIELFSTEKKDKNDSEREPSKKIEKELKPYGSSAINILKEKKKREKHREKWRDEKERHRDRHADGLLRHHRDELLRHHRDEQKPATRDKDSPPRVLKDKSRDEGPRLGDAKLKEKFKDGAEKEKGDPVKMSNGNDKVAPSKDPGKKDARPREKLLGDGDLMMTSFERMLSQKDLEIEERHKRHKERMKQMEKLRHRSGDPKLKEKAKPADDGRKKGLDIPAKKPPGLDPPFKDKKLKESTPIPPAAENKLHPASGADSKDWLAGPHMKEVLPASPRPDQSRPTGVPTPTSVLSCPSYEEVMHTPRTPSCSADDYADLVFDCADSQHSTPVPTAPTSACSPSFFDRFSVASSGLSENASQAPARPLSTNLYRSVSVDIRRTPEEEFSVGDKLFRQQSVPAASSYDSPMPPSMEDRAPLPPVPAEKFACLSPGYYSPDYGLPSPKVDALHCPPAAVVTVTPSPEGVFSSLQAKPSPSPRAELLVPSLEGALPPDLDTSEDQQATAAIIPPEPSYLEPLDEGPFSAVITEEPVEWAHPSEQALASSLIGGTSENPVSWPVGSDLLLKSPQRFPESPKRFCPADPLHSAAPGPFSASEAPYPAPPASPAPYALPVAEPGLEDVKDGVDAVPAAISTSEAAPYAPPSGLESFFSNCKSLPEAPLDVAPEPACVAAVAQVEALGPLENSFLDGSRGLSHLGQVEPVPWADAFAGPEDDLDLGPFSLPELPLQTKDAADGEAEPVEESLAPPEEMPPGAPGVINGGDVSTVVAEEPPALPPDQASTRLPAELEPEPSGEPKLDVALEAAVEAETVPEERARGDPDSSVEPAPVPPEQRPLGSGDQGAEAEGPPAASLCAPDGPAPNTVAQAQAADGAGPEDDTEASRAAAPAEGPPGGIQPEAAEPKPTAEAPKAPRVEEIPQRMTRNRAQMLANQSKQGPPPSEKECAPTPAPVTRAKARGSEDDDAQAQHPRKRRFQRSTQQLQQQLNTSTQQTREVIQQTLAAIVDAIKLDAIEPYHSDRANPYFEYLQIRKKIEEKRKILCCITPQAPQCYAEYVTYTGSYLLDGKPLSKLHIPVIAPPPSLAEPLKELFRQQEAVRGKLRLQHSIEREKLIVSCEQEILRVHCRAARTIANQAVPFSACTMLLDSEVYNMPLESQGDENKSVRDRFNARQFISWLQDVDDKYDRMKTCLLMRQQHEAAALNAVQRMEWQLKVQELDPAGHKSLCVNEVPSFYVPMVDVNDDFVLLPA

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
35	Phosphorylation	KKDKDKVSLTKTPKL CCCCCCCCCCCCCCC	35.74	20068231
63	Phosphorylation	SKRKLPFTAGANGEQ HHCCCCCCCCCCCCC	23.42	20873877
73	Phosphorylation	ANGEQKDSDTEKQGP CCCCCCCCCCCCCCH	54.17	67054421
75	O-linked_Glycosylation	GEQKDSDTEKQGPER CCCCCCCCCCCCHHH	49.38	30379171
75	Phosphorylation	GEQKDSDTEKQGPER CCCCCCCCCCCCHHH	49.38	27794612
91	Phosphorylation	RIKKEPVTRKAGLLF HCCCCCCCHHHHHHH	36.85	-
103	Phosphorylation	LLFGMGLSGIRAGYP HHHHCCCCCHHCCCC	26.84	24719451
109	Phosphorylation	LSGIRAGYPLSERQQ CCCHHCCCCCCHHHH	10.46	23401153
112	Phosphorylation	IRAGYPLSERQQVAL HHCCCCCCHHHHHHH	26.65	23401153
141	Phosphorylation	DTTPKHPSQSTVCQK CCCCCCCCCCCCCCC	36.16	20873877
143	Phosphorylation	TPKHPSQSTVCQKGT CCCCCCCCCCCCCCC	27.43	30177828
144	Phosphorylation	PKHPSQSTVCQKGTP CCCCCCCCCCCCCCC	20.05	30177828
150	Phosphorylation	STVCQKGTPNSASKT CCCCCCCCCCCCCCC	26.74	30576142
153	Phosphorylation	CQKGTPNSASKTKDK CCCCCCCCCCCCHHH	34.81	20873877
155	Phosphorylation	KGTPNSASKTKDKVN CCCCCCCCCCHHHHH	40.45	30576142
158	Methylation	PNSASKTKDKVNKRN CCCCCCCHHHHHHHC	60.32	23644510
160	Methylation	SASKTKDKVNKRNER CCCCCHHHHHHHCHH	49.62	23644510
213	Phosphorylation	HEACNRGYYDVAKQL HHHHHCCHHHHHHHH	8.02	6144479
214	Phosphorylation	EACNRGYYDVAKQLL HHHHCCHHHHHHHHH	13.53	18491316
229	Phosphorylation	AAGAEVNTKGLDDDT HCCCCEECCCCCCCC	31.50	21406692
236	Phosphorylation	TKGLDDDTPLHDAAN CCCCCCCCCHHHCCC	34.44	21406692
247	Phosphorylation	DAANNGHYKVVKLLL HCCCCCCHHHHHHHH	13.58	21406692
276	Phosphorylation	TPLKVANSPTMVNLL CCCCCCCCCCHHHHH	16.41	29255136
277	Phosphorylation	PLKVANSPTMVNLLL CCCCCCCCCHHHHHC	25.07	18669648
278	Phosphorylation	LKVANSPTMVNLLLG CCCCCCCCHHHHHCC	33.31	29255136
347	Phosphorylation	TAPVKDEYEFDEDDE CCCCCCCCCCCCCCC	31.84	27642862
377	Phosphorylation	DYRKETKSNSFISIP HHHHHCCCCCCCCCC	45.16	125683199
379	Phosphorylation	RKETKSNSFISIPKM HHHCCCCCCCCCCCE	30.92	25159151
382	Phosphorylation	TKSNSFISIPKMEVK CCCCCCCCCCCEEEE	30.72	24505115
390	Phosphorylation	IPKMEVKSYTKNNTI CCCEEEEEECCCCCC	43.12	27660485
391	Phosphorylation	PKMEVKSYTKNNTIA CCEEEEEECCCCCCC	18.93	19835603
392	Phosphorylation	KMEVKSYTKNNTIAP CEEEEEECCCCCCCC	34.09	19835603
396	Phosphorylation	KSYTKNNTIAPKKAS EEECCCCCCCCCCCC	28.10	19835603
408	Phosphorylation	KASHRILSDTSDEED CCCCCCCCCCCCCCC	36.15	25159151
409	Phosphorylation	ASHRILSDTSDEEDA CCCCCCCCCCCCCCC	46.94	18669648
410	Phosphorylation	SHRILSDTSDEEDAS CCCCCCCCCCCCCCC	34.40	25159151
411	Phosphorylation	HRILSDTSDEEDASV CCCCCCCCCCCCCCC	48.27	25159151
412	Phosphorylation	RILSDTSDEEDASVT CCCCCCCCCCCCCCE	66.45	18669648
417	Phosphorylation	TSDEEDASVTVGTGE CCCCCCCCCEECCCC	30.55	20068231
419	Phosphorylation	DEEDASVTVGTGEKL CCCCCCCEECCCCEE	15.66	21406692
422	Phosphorylation	DASVTVGTGEKLRLS CCCCEECCCCEEEEE	37.52	27251275
429	Phosphorylation	TGEKLRLSAHTILPG CCCEEEEEEEECCCC	16.15	72267977
432	Phosphorylation	KLRLSAHTILPGSKT EEEEEEEECCCCCCC	24.75	28450419
437	Phosphorylation	AHTILPGSKTREPSN EEECCCCCCCCCCCH	28.99	25159151
473	Phosphorylation	EVRFGKRSDKFCSSE CCCCCCCCCCCCCCC	48.95	50565289
486	Phosphorylation	SESESESSESGEDDR CCCCCCCCCCCCCCH	31.56	30576142
488	Phosphorylation	SESESSESGEDDRDS CCCCCCCCCCCCHHH	49.81	30576142
495	Phosphorylation	SGEDDRDSLGSSGCL CCCCCHHHCCCCCCC	35.21	30576142
498	Phosphorylation	DDRDSLGSSGCLKGS CCHHHCCCCCCCCCC	28.93	26074081
499	Phosphorylation	DRDSLGSSGCLKGSP CHHHCCCCCCCCCCC	31.56	26074081
505	Phosphorylation	SSGCLKGSPLVLKDP CCCCCCCCCEEECCH	17.30	22617229
555	Phosphorylation	TDNWKTISSPAWSEV CCCCCEECCCCHHHH	35.19	25627689
556	Phosphorylation	DNWKTISSPAWSEVS CCCCEECCCCHHHHH	18.13	25627689
560	Phosphorylation	TISSPAWSEVSSLSD EECCCCHHHHHCCCC	30.17	30108239
563	Phosphorylation	SPAWSEVSSLSDSTR CCCHHHHHCCCCCCC	22.85	23663014
564	Phosphorylation	PAWSEVSSLSDSTRT CCHHHHHCCCCCCCC	36.75	23663014
566	Phosphorylation	WSEVSSLSDSTRTRL HHHHHCCCCCCCCCC	31.31	23663014
568	Phosphorylation	EVSSLSDSTRTRLTS HHHCCCCCCCCCCCC	19.20	30108239
569	Phosphorylation	VSSLSDSTRTRLTSE HHCCCCCCCCCCCCC	40.84	30108239
574	Phosphorylation	DSTRTRLTSESDYSS CCCCCCCCCCCCCCC	27.45	28290473
575	Phosphorylation	STRTRLTSESDYSSE CCCCCCCCCCCCCCC	39.43	22210691
577	Phosphorylation	RTRLTSESDYSSEGS CCCCCCCCCCCCCCC	41.43	28290473
580	Phosphorylation	LTSESDYSSEGSSVE CCCCCCCCCCCCCHH	27.23	68729369
581	Phosphorylation	TSESDYSSEGSSVES CCCCCCCCCCCCHHC	39.48	22210691
584	Phosphorylation	SDYSSEGSSVESLKP CCCCCCCCCHHCCCC	27.45	22210691
594	Acetylation	ESLKPVRKRQEHRKR HCCCCHHHHHHHHHH	59.68	30586917
603	Phosphorylation	QEHRKRASLSEKKSP HHHHHHHCCCCCCCC	36.14	26434776
605	Phosphorylation	HRKRASLSEKKSPFL HHHHHCCCCCCCCCH	44.89	26434776
609	Phosphorylation	ASLSEKKSPFLSSAE HCCCCCCCCCHHCCC	31.77	30266825
613	Phosphorylation	EKKSPFLSSAEGAVP CCCCCCHHCCCCCCC	28.07	30266825
614	Phosphorylation	KKSPFLSSAEGAVPK CCCCCHHCCCCCCCC	32.27	30804265
631	Acetylation	KEGKVVKKHKTKHKH CCCCEEECCCCCCCC	38.43	7709749
639	Acetylation	HKTKHKHKNKEKGQC CCCCCCCCCCCCCCC	74.62	30586905
641	Acetylation	TKHKHKNKEKGQCSI CCCCCCCCCCCCCCC	66.65	30586911
647	Phosphorylation	NKEKGQCSISQELKL CCCCCCCCCCHHHCC	19.86	28450419
649	Phosphorylation	EKGQCSISQELKLKS CCCCCCCCHHHCCCE	10.99	28450419
656	Phosphorylation	SQELKLKSFTYEYED CHHHCCCEEEEEECC	33.00	29214152
661	Phosphorylation	LKSFTYEYEDSKQKS CCEEEEEECCCCCCC	18.02	27642862
670	Ubiquitination	DSKQKSDKAILLEND CCCCCCCCEEEECCC	44.40	29967540
679	Phosphorylation	ILLENDLSTENKLKV EEECCCCCHHHHHHH	36.22	28555341
702	Acetylation	KKEEKLSKMKLEEKE HHHHHHHHCCHHHHH	50.95	7851869
719	Acetylation	FKDEKSLKRIKDTNK CCCHHHHHHHHHCCH	60.20	69299
752	Phosphorylation	ERSLKEKSPKEEKLR HHHHHHCCHHHHHHH	42.15	24719451
812	Phosphorylation	EKVYREDSAFDEYCN HHCCCCCHHHHHHHC	26.53	28450419
817	Phosphorylation	EDSAFDEYCNKNQFL CCHHHHHHHCCCHHC	11.81	27642862
820	Ubiquitination	AFDEYCNKNQFLENE HHHHHHCCCHHCCCC	48.87	29967540
829	Phosphorylation	QFLENEDTKFSLSDD HHCCCCCCCCCCCHH	28.01	27732954
832	Phosphorylation	ENEDTKFSLSDDQRD CCCCCCCCCCHHHHH	28.64	23927012
834	Phosphorylation	EDTKFSLSDDQRDRW CCCCCCCCHHHHHHC	37.63	30266825
835	Phosphorylation	DTKFSLSDDQRDRWF CCCCCCCHHHHHHCH	62.45	18669648
843	Phosphorylation	DQRDRWFSDLSDSSF HHHHHCHHCCCCCCC	30.59	20873877
844	Phosphorylation	QRDRWFSDLSDSSFD HHHHCHHCCCCCCCC	40.49	17081983
846	Phosphorylation	DRWFSDLSDSSFDFK HHCHHCCCCCCCCCC	40.20	20873877
847	Phosphorylation	RWFSDLSDSSFDFKG HCHHCCCCCCCCCCC	56.45	17081983
848	Phosphorylation	WFSDLSDSSFDFKGE CHHCCCCCCCCCCCC	29.54	20873877
849	Phosphorylation	FSDLSDSSFDFKGED HHCCCCCCCCCCCCC	33.55	20873877
850	Phosphorylation	SDLSDSSFDFKGEDS HCCCCCCCCCCCCCC	17.31	17081983
857	Phosphorylation	FDFKGEDSWDSPVTD CCCCCCCCCCCCCCC	28.60	23663014
860	Phosphorylation	KGEDSWDSPVTDYRD CCCCCCCCCCCCHHH	18.27	72248765
863	Phosphorylation	DSWDSPVTDYRDMKS CCCCCCCCCHHHCCC	30.60	27732954
865	Phosphorylation	WDSPVTDYRDMKSDS CCCCCCCHHHCCCCH	10.11	27794612
880	O-linked_Glycosylation	VAKLILETVKEDSKE HHHHHHHHHHHHHHH	33.17	30379171
885	O-linked_Glycosylation	LETVKEDSKERRRDS HHHHHHHHHHHHHHH	37.19	30379171
892	O-linked_Glycosylation	SKERRRDSRAREKRD HHHHHHHHHHHHHHH	26.48	30379171
917	Phosphorylation	RDYLDKNSEKRKEQT HHHCCCCHHHHHHHH	50.68	24505115
933	Phosphorylation	KHKSVPGYLSEKDKK HHHCCCCCCCHHHHH	10.86	18083107
935	Phosphorylation	KSVPGYLSEKDKKRR HCCCCCCCHHHHHHH	33.83	23312004
937	Acetylation	VPGYLSEKDKKRRES CCCCCCHHHHHHHHH	72.04	25953088
939	Acetylation	GYLSEKDKKRRESAE CCCCHHHHHHHHHHH	60.28	25953088
957	Phosphorylation	DRKDALESCKERRDG CHHHHHHHHHHHCCC	31.19	46163737
983	Phosphorylation	LKECGCESGFKDKSD HHHCCCCCCCCCCCC	54.31	46163741
989	Phosphorylation	ESGFKDKSDGDFGKG CCCCCCCCCCCCCCC	57.89	28985074
1041	Phosphorylation	DKDKSEKSILEKCQK CCCHHHHHHHHHHHH	28.49	24719451
1079	Phosphorylation	KDKERKASLDQGKEK CHHHHHHHHHHHHHH	35.20	26657352
1112	Phosphorylation	DKKGKEKSWYIADIF CCCCCCCCEEEEECC	26.63	68710419
1114	Phosphorylation	KGKEKSWYIADIFTD CCCCCCEEEEECCCC	8.04	68710425
1120	Phosphorylation	WYIADIFTDESEDDR EEEEECCCCCCCCCH	38.91	22617229
1121	Phosphorylation	YIADIFTDESEDDRD EEEECCCCCCCCCHH	46.83	18669648
1123	Phosphorylation	ADIFTDESEDDRDSC EECCCCCCCCCHHCC	49.49	22617229
1124	Phosphorylation	DIFTDESEDDRDSCM ECCCCCCCCCHHCCC	62.98	18669648
1129	Phosphorylation	ESEDDRDSCMGSGFK CCCCCHHCCCCCCCC	13.59	27732954
1133	Phosphorylation	DRDSCMGSGFKMGEA CHHCCCCCCCCCCCH	17.74	27732954
1141	Phosphorylation	GFKMGEASDLPRTDG CCCCCCHHHCCCCCC	35.06	29083192
1146	Phosphorylation	EASDLPRTDGLQEKE CHHHCCCCCCCCHHH	32.26	23403867
1168	Phosphorylation	SDRHRKSSDKQHPER HHHHHHCCCCCCHHH	52.44	7858611
1225	Phosphorylation	KDRKDRASVDSTQDK HHHHHHHCCCCHHHH	27.61	25849741
1279	Phosphorylation	RSADAEKSLLEKLEE HHHHHHHHHHHHHHH	29.68	24719451
1292	Phosphorylation	EEEALHEYREDSNDK HHHHHHHHHHCCCCC	14.46	28102081
1296	Phosphorylation	LHEYREDSNDKISEV HHHHHHCCCCCCCCC	42.02	25159151
1304	Phosphorylation	NDKISEVSSDSFTDR CCCCCCCCCCCCCCC	25.11	23663014
1305	Phosphorylation	DKISEVSSDSFTDRG CCCCCCCCCCCCCCC	42.31	25849741
1307	Phosphorylation	ISEVSSDSFTDRGQE CCCCCCCCCCCCCCC	31.81	23663014
1309	Phosphorylation	EVSSDSFTDRGQEPG CCCCCCCCCCCCCCC	28.83	23663014
1324	Phosphorylation	LTAFLEVSFTEPPGD CEEEEEEEECCCCCC	19.64	29116813
1326	Phosphorylation	AFLEVSFTEPPGDDK EEEEEEECCCCCCCC	39.82	29116813
1353	Phosphorylation	EKERHRHSSSSSKKS HHHHHCCCCCHHHHH	31.69	25852190
1354	Phosphorylation	KERHRHSSSSSKKSH HHHHCCCCCHHHHHH	28.28	25852190
1355	Phosphorylation	ERHRHSSSSSKKSHD HHHCCCCCHHHHHHH	41.46	25852190
1356	Phosphorylation	RHRHSSSSSKKSHDR HHCCCCCHHHHHHHH	48.39	25852190
1357	Phosphorylation	HRHSSSSSKKSHDRE HCCCCCHHHHHHHHH	46.15	25852190
1389	Phosphorylation	EGGSRKDSGQYEKDF CCCCCCCCCCCCCHH	30.72	28985074
1392	Phosphorylation	SRKDSGQYEKDFLEA CCCCCCCCCCHHHHH	28.59	26434776
1419	Phosphorylation	IEDELDKTIELFSTE HHHHHHHHHHHHHCC	21.25	25159151
1420	Phosphorylation	EDELDKTIELFSTEK HHHHHHHHHHHHCCC	5.51	18669648
1425	O-linked_Glycosylation	KTIELFSTEKKDKND HHHHHHHCCCCCCCC	44.48	30379171
1446	Sumoylation	KKIEKELKPYGSSAI HHHHHHHHCCCHHHH	36.97	-
1446	Sumoylation	KKIEKELKPYGSSAI HHHHHHHHCCCHHHH	36.97	-
1448	Phosphorylation	IEKELKPYGSSAINI HHHHHHCCCHHHHHH	28.22	29083192
1450	Phosphorylation	KELKPYGSSAINILK HHHHCCCHHHHHHHH	15.68	24850871
1451	Phosphorylation	ELKPYGSSAINILKE HHHCCCHHHHHHHHH	28.89	24850871
1509	Phosphorylation	PATRDKDSPPRVLKD CCCCCCCCCCCCCCC	42.41	25159151
1510	Phosphorylation	ATRDKDSPPRVLKDK CCCCCCCCCCCCCCC	30.74	17081983
1559	Acetylation	NDKVAPSKDPGKKDA CCCCCCCCCCCCCCC	67.87	19820981
1559	Ubiquitination	NDKVAPSKDPGKKDA CCCCCCCCCCCCCCC	67.87	-
1564	Ubiquitination	PSKDPGKKDARPREK CCCCCCCCCCCCHHH	63.64	-
1581	Phosphorylation	GDGDLMMTSFERMLS CCCCCCHHHHHHHHH	19.12	22199227
1582	Phosphorylation	DGDLMMTSFERMLSQ CCCCCHHHHHHHHHH	13.76	50565305
1588	Phosphorylation	TSFERMLSQKDLEIE HHHHHHHHHHHHHHH	26.33	46163719
1615	Phosphorylation	MEKLRHRSGDPKLKE HHHHHHHCCCHHHHH	41.23	24719451
1658	Phosphorylation	DKKLKESTPIPPAAE CCCCCCCCCCCCHHH	26.74	21815630
1692	Phosphorylation	MKEVLPASPRPDQSR HHHCCCCCCCCCCCC	21.36	25849741
1698	Phosphorylation	ASPRPDQSRPTGVPT CCCCCCCCCCCCCCC	47.83	26074081
1701	Phosphorylation	RPDQSRPTGVPTPTS CCCCCCCCCCCCCCC	50.10	26074081
1705	Phosphorylation	SRPTGVPTPTSVLSC CCCCCCCCCCCHHCC	36.47	26074081
1707	Phosphorylation	PTGVPTPTSVLSCPS CCCCCCCCCHHCCCC	33.67	26074081
1708	Phosphorylation	TGVPTPTSVLSCPSY CCCCCCCCHHCCCCH	23.43	26074081
1711	Phosphorylation	PTPTSVLSCPSYEEV CCCCCHHCCCCHHHH	23.09	26074081
1714	Phosphorylation	TSVLSCPSYEEVMHT CCHHCCCCHHHHCCC	49.88	26074081
1715	Phosphorylation	SVLSCPSYEEVMHTP CHHCCCCHHHHCCCC	10.97	26074081
1754	Phosphorylation	PVPTAPTSACSPSFF CCCCCCCCCCCHHHH	26.64	28348404
1757	Phosphorylation	TAPTSACSPSFFDRF CCCCCCCCHHHHHHH	24.24	26074081
1759	Phosphorylation	PTSACSPSFFDRFSV CCCCCCHHHHHHHHH	23.42	26074081
1790	Phosphorylation	LSTNLYRSVSVDIRR CCCCCCCEEEEECCC	12.75	30266825
1792	Phosphorylation	TNLYRSVSVDIRRTP CCCCCEEEEECCCCC	18.47	23401153
1793	Phosphorylation	NLYRSVSVDIRRTPE CCCCEEEEECCCCCH	7.13	18669648
1798	Phosphorylation	VSVDIRRTPEEEFSV EEEECCCCCHHHCCC	25.79	30266825
1804	Phosphorylation	RTPEEEFSVGDKLFR CCCHHHCCCCHHHHH	28.59	23927012
1814	Phosphorylation	DKLFRQQSVPAASSY HHHHHCCCCCCCCCC	23.02	28450419
1819	Phosphorylation	QQSVPAASSYDSPMP CCCCCCCCCCCCCCC	31.38	28450419
1820	Phosphorylation	QSVPAASSYDSPMPP CCCCCCCCCCCCCCC	28.38	28450419
1821	Phosphorylation	SVPAASSYDSPMPPS CCCCCCCCCCCCCCC	20.25	26074081
1823	Phosphorylation	PAASSYDSPMPPSME CCCCCCCCCCCCCCC	18.18	26074081
1828	Phosphorylation	YDSPMPPSMEDRAPL CCCCCCCCCCCCCCC	29.00	26074081
1847	Phosphorylation	AEKFACLSPGYYSPD HHHEECCCCCCCCCC	19.03	25159151
1848	Phosphorylation	EKFACLSPGYYSPDY HHEECCCCCCCCCCC	23.12	18669648
1850	Phosphorylation	FACLSPGYYSPDYGL EECCCCCCCCCCCCC	12.26	23663014
1851	Phosphorylation	ACLSPGYYSPDYGLP ECCCCCCCCCCCCCC	21.46	25159151
1852	Phosphorylation	CLSPGYYSPDYGLPS CCCCCCCCCCCCCCC	11.65	25159151
1853	Phosphorylation	LSPGYYSPDYGLPSP CCCCCCCCCCCCCCC	23.79	18669648
1855	Phosphorylation	PGYYSPDYGLPSPKV CCCCCCCCCCCCCCC	24.77	30108239
1859	Phosphorylation	SPDYGLPSPKVDALH CCCCCCCCCCCCCCC	42.25	25159151
1860	Phosphorylation	PDYGLPSPKVDALHC CCCCCCCCCCCCCCC	38.46	18669648
1874	Phosphorylation	CPPAAVVTVTPSPEG CCCCEEEEEECCCCC	16.44	30266825
1876	Phosphorylation	PAAVVTVTPSPEGVF CCEEEEEECCCCCCH	14.53	30266825
1878	Phosphorylation	AVVTVTPSPEGVFSS EEEEEECCCCCCHHH	26.64	30266825
1884	Phosphorylation	PSPEGVFSSLQAKPS CCCCCCHHHCCCCCC	27.94	30266825
1885	Phosphorylation	SPEGVFSSLQAKPSP CCCCCHHHCCCCCCC	17.03	30266825
1891	Phosphorylation	SSLQAKPSPSPRAEL HHCCCCCCCCCCHHH	36.98	30266825
1893	Phosphorylation	LQAKPSPSPRAELLV CCCCCCCCCCHHHHC	31.21	30266825
1983	Phosphorylation	GSDLLLKSPQRFPES CCCCEECCCCCCCCC	26.66	30266825
1984	Phosphorylation	SDLLLKSPQRFPESP CCCEECCCCCCCCCC	27.98	17081983
1990	Phosphorylation	SPQRFPESPKRFCPA CCCCCCCCCCCCCCC	35.64	30266825
1991	Phosphorylation	PQRFPESPKRFCPAD CCCCCCCCCCCCCCC	30.13	17081983
2002	Phosphorylation	CPADPLHSAAPGPFS CCCCCCCCCCCCCCC	33.53	26074081
2009	Phosphorylation	SAAPGPFSASEAPYP CCCCCCCCCCCCCCC	33.74	26074081
2011	Phosphorylation	APGPFSASEAPYPAP CCCCCCCCCCCCCCC	32.85	26074081
2015	Phosphorylation	FSASEAPYPAPPASP CCCCCCCCCCCCCCC	21.05	26074081
2021	Phosphorylation	PYPAPPASPAPYALP CCCCCCCCCCCCCCC	27.63	26074081
2025	Phosphorylation	PPASPAPYALPVAEP CCCCCCCCCCCCCCC	23.91	26074081
2137	Phosphorylation	DLDLGPFSLPELPLQ CCCCCCCCCCCCCCC	46.26	26074081
2208	Phosphorylation	AELEPEPSGEPKLDV CCCCCCCCCCCCHHH	54.87	29970186
2320	Phosphorylation	EAAEPKPTAEAPKAP CCCCCCCCCCCCCCC	43.16	26657352
2374	Phosphorylation	TRAKARGSEDDDAQA CHHHHCCCCCCCHHH	32.09	25849741
2393	Phosphorylation	KRRFQRSTQQLQQQL HHHHHHHHHHHHHHH	23.64	28555341
2402	Phosphorylation	QLQQQLNTSTQQTRE HHHHHHHHCHHHHHH	41.57	22271179
2403	Phosphorylation	LQQQLNTSTQQTREV HHHHHHHCHHHHHHH	24.12	28555341
2544	Phosphorylation	VHCRAARTIANQAVP HHHHHHHHHHHHCCC	21.51	50565281
2553	Phosphorylation	ANQAVPFSACTMLLD HHHCCCHHHHHHHHC	19.16	28985074
2570	Phosphorylation	VYNMPLESQGDENKS HHCCCCHHCCCCCCC	47.34	28985074

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of ANR11_HUMAN !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of ANR11_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of ANR11_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
NCOA2_HUMAN	NCOA2	physical	15184363
NCOA3_HUMAN	NCOA3	physical	15184363
HDAC3_HUMAN	HDAC3	physical	15184363
RIMB1_HUMAN	BZRAP1	physical	24722188
CDA7L_HUMAN	CDCA7L	physical	24722188
GOGA2_HUMAN	GOLGA2	physical	24722188
HOOK2_HUMAN	HOOK2	physical	24722188
IKZF1_HUMAN	IKZF1	physical	24722188
CEP44_HUMAN	CEP44	physical	24722188
LZTS2_HUMAN	LZTS2	physical	24722188
MKRN3_HUMAN	MKRN3	physical	24722188
MYOME_HUMAN	PDE4DIP	physical	24722188
TFP11_HUMAN	TFIP11	physical	24722188
TRAF2_HUMAN	TRAF2	physical	24722188
TRI37_HUMAN	TRIM37	physical	24722188
NCOA1_HUMAN	NCOA1	physical	15184363

Drug and Disease Associations

Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
148050	KBG syndrome (KBGS)
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of ANR11_HUMAN

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"Quantitative phosphoproteomic analysis of T cell receptor signalingreveals system-wide modulation of protein-protein interactions."; Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K.,Rodionov V., Han D.K.; Sci. Signal. 2:RA46-RA46(2009). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-276; SER-408; THR-410;SER-411 AND THR-1419, AND MASS SPECTROMETRY.	19690332 [Abstract]
"Lys-N and trypsin cover complementary parts of the phosphoproteome ina refined SCX-based approach."; Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J.,Mohammed S.; Anal. Chem. 81:4493-4501(2009). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-276, AND MASSSPECTROMETRY.	19413330 [Abstract]
"A quantitative atlas of mitotic phosphorylation."; Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E.,Elledge S.J., Gygi S.P.; Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-276; SER-408; THR-410;SER-411; SER-834; THR-1120; SER-1123; THR-1419; SER-1792; SER-1847;SER-1852 AND SER-1859, AND MASS SPECTROMETRY.	18669648 [Abstract]
"Global, in vivo, and site-specific phosphorylation dynamics insignaling networks."; Olsen J.V., Blagoev B., Gnad F., Macek B., Kumar C., Mortensen P.,Mann M.; Cell 127:635-648(2006). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-408; THR-410; SER-411;SER-843; SER-846; SER-848; SER-849; SER-1509; SER-1983 AND SER-1990,AND MASS SPECTROMETRY.	17081983 [Abstract]