ANGL7_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ANGL7_HUMAN
• UniProt AC: O43827
• Protein Name: Angiopoietin-related protein 7
• Gene Name: ANGPTL7
• Organism: Homo sapiens (Human).
• Sequence Length: 346
• Subcellular Localization: Secreted .
• Protein Sequence: MLKKPLSAVTWLCIFIVAFVSHPAWLQKLSKHKTPAQPQLKAANCCEEVKELKAQVANLSSLLSELNKKQERDWVSVVMQVMELESNSKRMESRLTDAESKYSEMNNQIDIMQLQAAQTVTQTSADAIYDCSSLYQKNYRISGVYKLPPDDFLGSPELEVFCDMETSGGGWTIIQRRKSGLVSFYRDWKQYKQGFGSIRGDFWLGNEHIHRLSRQPTRLRVEMEDWEGNLRYAEYSHFVLGNELNSYRLFLGNYTGNVGNDALQYHNNTAFSTKDKDNDNCLDKCAQLRKGGYWYNCCTDSNLNGVYYRLGEHNKHLDGITWYGWHGSTYSLKRVEMKIRPEDFKP

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
58	N-linked_Glycosylation	ELKAQVANLSSLLSE HHHHHHHCHHHHHHH	41.41	UniProtKB CARBOHYD
60	Phosphorylation	KAQVANLSSLLSELN HHHHHCHHHHHHHHH	20.81	24719451
64	Phosphorylation	ANLSSLLSELNKKQE HCHHHHHHHHHHHCC	45.38	24719451
145	Phosphorylation	NYRISGVYKLPPDDF CCCEEEEEECCHHHC	15.44	46163257
197	Phosphorylation	QYKQGFGSIRGDFWL HHHHCCCCCCCCEEE	13.57	24719451
253	N-linked_Glycosylation	SYRLFLGNYTGNVGN EEEEECCCCCCCCCC	33.08	UniProtKB CARBOHYD
267	N-linked_Glycosylation	NDALQYHNNTAFSTK CCHHHHCCCCCCCCC	42.48	UniProtKB CARBOHYD
331	Phosphorylation	GWHGSTYSLKRVEMK ECCCCEEEEEEEEEE	27.74	24719451
338	Methylation	SLKRVEMKIRPEDFK EEEEEEEEECHHHCC	23.27	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ANGL7_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ANGL7_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ANGL7_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
ANGL7_HUMAN	ANGPTL7	physical	11682471
A4_HUMAN	APP	physical	21832049
DHB8_HUMAN	HSD17B8	physical	28514442
NMT1_HUMAN	NMT1	physical	28514442
EDEM3_HUMAN	EDEM3	physical	28514442
EDEM2_HUMAN	EDEM2	physical	28514442
KBTB7_HUMAN	KBTBD7	physical	28514442
GBB2_HUMAN	GNB2	physical	28514442
TCPZ_HUMAN	CCT6A	physical	28514442
TCPB_HUMAN	CCT2	physical	28514442
TCPA_HUMAN	TCP1	physical	28514442
TXD11_HUMAN	TXNDC11	physical	28514442
TCPH_HUMAN	CCT7	physical	28514442

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.