ZN490_HUMAN - dbPTM
ZN490_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID ZN490_HUMAN
UniProt AC Q9ULM2
Protein Name Zinc finger protein 490
Gene Name ZNF490
Organism Homo sapiens (Human).
Sequence Length 529
Subcellular Localization Nucleus .
Protein Description May be involved in transcriptional regulation..
Protein Sequence MRRNSSLSFQMERPLEEQVQSKWSSSQGRTGTGGSDVLQMQNSEHHGQSIKTQTDSISLEDVAVNFTLEEWALLDPGQRNIYRDVMRATFKNLACIGEKWKDQDIEDEHKNQGRNLRSPMVEALCENKEDCPCGKSTSQIPDLNTNLETPTGLKPCDCSVCGEVFMHQVSLNRHMRSHTEQKPNECHEYGEKPHKCKECGKTFTRSSSIRTHERIHTGEKPYECKECGKAFAFLFSFRNHIRIHTGETPYECKECGKAFRYLTALRRHEKNHTGEKPYKCKQCGKAFIYYQPFLTHERTHTGEKPYECKQCGKAFSCPTYLRSHEKTHTGEKPFVCRECGRAFFSHSSLRKHVKTHTGVQPYTCKKCGEAFKSSSSCEVHERTHFGEKPYECKQCGKAFNSSSYLQLHERVHTGEKTYECKECGKAFLYSTHFRIHERTHTREKPYECKQCGRVFIYFSHLRRHERSHTGVKPCECKQCGKAFTCLNSLKVHKRIHTGERPFQCRQCGKAFSYSKSLHVHERTHSRQKP
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
5Phosphorylation---MRRNSSLSFQME
---CCCCCCCCEECC		30.7428348404
6Phosphorylation--MRRNSSLSFQMER
--CCCCCCCCEECCC		31.4228348404
118PhosphorylationNQGRNLRSPMVEALC
HCCCCCCCHHHHHHH		22.1028450419
145PhosphorylationSQIPDLNTNLETPTG
CCCCCCCCCCCCCCC		48.7727050516
201UbiquitinationHKCKECGKTFTRSSS
CCCCCCCCEEECCHH		52.72-
217PhosphorylationRTHERIHTGEKPYEC
CCCCCEECCCCCEEC		44.6729496963
225SumoylationGEKPYECKECGKAFA
CCCCEECCHHHHHHH		44.06-
225SumoylationGEKPYECKECGKAFA
CCCCEECCHHHHHHH		44.06-
236PhosphorylationKAFAFLFSFRNHIRI
HHHHHHHHCCCCEEE		25.9924719451
253SumoylationGETPYECKECGKAFR
CCCCCCHHHHHHHHH		44.06-
253SumoylationGETPYECKECGKAFR
CCCCCCHHHHHHHHH		44.06-
263PhosphorylationGKAFRYLTALRRHEK
HHHHHHHHHHHHHHC		18.0824719451
299PhosphorylationPFLTHERTHTGEKPY
CCCCCCCCCCCCCCC		22.3229396449
301PhosphorylationLTHERTHTGEKPYEC
CCCCCCCCCCCCCCC		46.5629496963
304UbiquitinationERTHTGEKPYECKQC
CCCCCCCCCCCCCCC		55.0022505724
309SumoylationGEKPYECKQCGKAFS
CCCCCCCCCCCCEEC		36.36-
309SumoylationGEKPYECKQCGKAFS
CCCCCCCCCCCCEEC		36.36-
327PhosphorylationYLRSHEKTHTGEKPF
HHHCCCCCCCCCCCE		22.9922210691
393SumoylationGEKPYECKQCGKAFN
CCCCEEECCCCCCCC		36.36-
393SumoylationGEKPYECKQCGKAFN
CCCCEEECCCCCCCC		36.36-
488PhosphorylationKAFTCLNSLKVHKRI
CEEEHHHHCCCCCCC		19.3328555341
497PhosphorylationKVHKRIHTGERPFQC
CCCCCCCCCCCCEEC		38.0628555341
513PhosphorylationQCGKAFSYSKSLHVH
CCCCCEECCCCEECC		17.4224719451
523PhosphorylationSLHVHERTHSRQKP-
CEECCCCCCCCCCC-		22.6324719451
525PhosphorylationHVHERTHSRQKP---
ECCCCCCCCCCC---		35.4824719451
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of ZN490_HUMAN !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of ZN490_HUMAN !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of ZN490_HUMAN !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
CC136_HUMANCCDC136physical
25416956
CEP70_HUMANCEP70physical
25416956
TSG10_HUMANTSGA10physical
25416956
NDEL1_HUMANNDEL1physical
25416956
LZTS2_HUMANLZTS2physical
25416956
TRI41_HUMANTRIM41physical
25416956
K1C40_HUMANKRT40physical
25416956
KR107_HUMANKRTAP10-7physical
25416956
KR103_HUMANKRTAP10-3physical
25416956
TRI39_HUMANTRIM39physical
28514442
RL36L_HUMANRPL36ALphysical
28514442
EF1A2_HUMANEEF1A2physical
28514442
TOM34_HUMANTOMM34physical
28514442
PRD15_HUMANPRDM15physical
28514442
RL26L_HUMANRPL26L1physical
28514442
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of ZN490_HUMAN

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Related Literatures of Post-Translational Modification

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