dbPTM

ZEB2_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	ZEB2_HUMAN
UniProt AC	O60315
Protein Name	Zinc finger E-box-binding homeobox 2
Gene Name	ZEB2
Organism	Homo sapiens (Human).
Sequence Length	1214
Subcellular Localization	Nucleus .
Protein Description	Transcriptional inhibitor that binds to DNA sequence 5'-CACCT-3' in different promoters. Represses transcription of E-cadherin..
Protein Sequence	MKQPIMADGPRCKRRKQANPRRKNVVNYDNVVDTGSETDEEDKLHIAEDDGIANPLDQETSPASVPNHESSPHVSQALLPREEEEDEIREGGVEHPWHNNEILQASVDGPEEMKEDYDTMGPEATIQTAINNGTVKNANCTSDFEEYFAKRKLEERDGHAVSIEEYLQRSDTAIIYPEAPEELSRLGTPEANGQEENDLPPGTPDAFAQLLTCPYCDRGYKRLTSLKEHIKYRHEKNEENFSCPLCSYTFAYRTQLERHMVTHKPGTDQHQMLTQGAGNRKFKCTECGKAFKYKHHLKEHLRIHSGEKPYECPNCKKRFSHSGSYSSHISSKKCIGLISVNGRMRNNIKTGSSPNSVSSSPTNSAITQLRNKLENGKPLSMSEQTGLLKIKTEPLDFNDYKVLMATHGFSGTSPFMNGGLGATSPLGVHPSAQSPMQHLGVGMEAPLLGFPTMNSNLSEVQKVLQIVDNTVSRQKMDCKAEEISKLKGYHMKDPCSQPEEQGVTSPNIPPVGLPVVSHNGATKSIIDYTLEKVNEAKACLQSLTTDSRRQISNIKKEKLRTLIDLVTDDKMIENHNISTPFSCQFCKESFPGPIPLHQHERYLCKMNEEIKAVLQPHENIVPNKAGVFVDNKALLLSSVLSEKGMTSPINPYKDHMSVLKAYYAMNMEPNSDELLKISIAVGLPQEFVKEWFEQRKVYQYSNSRSPSLERSSKPLAPNSNPPTKDSLLPRSPVKPMDSITSPSIAELHNSVTNCDPPLRLTKPSHFTNIKPVEKLDHSRSNTPSPLNLSSTSSKNSHSSSYTPNSFSSEELQAEPLDLSLPKQMKEPKSIIATKNKTKASSISLDHNSVSSSSENSDEPLNLTFIKKEFSNSNNLDNKSTNPVFSMNPFSAKPLYTALPPQSAFPPATFMPPVQTSIPGLRPYPGLDQMSFLPHMAYTYPTGAATFADMQQRRKYQRKQGFQGELLDGAQDYMSGLDDMTDSDSCLSRKKIKKTESGMYACDLCDKTFQKSSSLLRHKYEHTGKRPHQCQICKKAFKHKHHLIEHSRLHSGEKPYQCDKCGKRFSHSGSYSQHMNHRYSYCKREAEEREAAEREAREKGHLEPTELLMNRAYLQSITPQGYSDSEERESMPRDGESEKEHEKEGEDGYGKLGRQDGDEEFEEEEEESENKSMDTDPETIRDEEETGDHSMDDSSEDGKMETKSDHEEDNMEDGM

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Ubiquitination	------MKQPIMADG ------CCCCCCCCC	75.88	32015554
11	Dimethylation	PIMADGPRCKRRKQA CCCCCCHHHHHHHCC	44.08	-
11	Methylation	PIMADGPRCKRRKQA CCCCCCHHHHHHHCC	44.08	115372855
28	Phosphorylation	RRKNVVNYDNVVDTG CCCCCCCCCCCCCCC	9.40	28450419
34	Phosphorylation	NYDNVVDTGSETDEE CCCCCCCCCCCCCHH	30.88	28450419
36	Phosphorylation	DNVVDTGSETDEEDK CCCCCCCCCCCHHHC	39.14	20363803
38	Phosphorylation	VVDTGSETDEEDKLH CCCCCCCCCHHHCCE	50.86	20363803
60	Phosphorylation	ANPLDQETSPASVPN CCCCCCCCCCCCCCC	34.08	19060867
61	Phosphorylation	NPLDQETSPASVPNH CCCCCCCCCCCCCCC	20.09	29449344
64	Phosphorylation	DQETSPASVPNHESS CCCCCCCCCCCCCCC	41.30	26471730
70	Phosphorylation	ASVPNHESSPHVSQA CCCCCCCCCCCHHHH	41.43	19060867
71	Phosphorylation	SVPNHESSPHVSQAL CCCCCCCCCCHHHHC	18.95	29449344
75	Phosphorylation	HESSPHVSQALLPRE CCCCCCHHHHCCCHH	13.50	29449344
118 (in isoform 2)	Phosphorylation	-	42.40	29507054
119	Phosphorylation	EMKEDYDTMGPEATI HHHHHHHCCCCCHHH	20.14	-
141	Phosphorylation	TVKNANCTSDFEEYF CCCCCCCCCCHHHHH	31.01	28165663
142	Phosphorylation	VKNANCTSDFEEYFA CCCCCCCCCHHHHHH	42.37	28450419
147	Phosphorylation	CTSDFEEYFAKRKLE CCCCHHHHHHHHHHH	11.14	-
162	Phosphorylation	ERDGHAVSIEEYLQR HCCCCEECHHHHHHH	25.68	28450419
176	Phosphorylation	RSDTAIIYPEAPEEL HCCCEEECCCCHHHH	6.73	30301811
184	Phosphorylation	PEAPEELSRLGTPEA CCCHHHHHHCCCCCC	28.83	25850435
188	Phosphorylation	EELSRLGTPEANGQE HHHHHCCCCCCCCCC	23.65	27251275
224	Phosphorylation	DRGYKRLTSLKEHIK CCCHHHHHHHHHHHH	35.73	28857561
225	Phosphorylation	RGYKRLTSLKEHIKY CCHHHHHHHHHHHHH	41.87	28857561
254	Phosphorylation	SYTFAYRTQLERHMV HHEEEHHHHHHHHCC	25.48	-
274	Phosphorylation	TDQHQMLTQGAGNRK CHHHHHHHCCCCCCE	21.44	-
285	Phosphorylation	GNRKFKCTECGKAFK CCCEEEECCCCHHHH	34.60	-
305	Phosphorylation	KEHLRIHSGEKPYEC HHHHEECCCCCCCCC	46.40	28450419
320	Phosphorylation	PNCKKRFSHSGSYSS CCCCCCCCCCCCCCC	22.30	28555341
322	Phosphorylation	CKKRFSHSGSYSSHI CCCCCCCCCCCCCCC	28.39	28555341
324	Phosphorylation	KRFSHSGSYSSHISS CCCCCCCCCCCCCCC	25.51	28555341
325	Phosphorylation	RFSHSGSYSSHISSK CCCCCCCCCCCCCCC	20.09	30576142
326	Phosphorylation	FSHSGSYSSHISSKK CCCCCCCCCCCCCCC	19.69	30576142
327	Phosphorylation	SHSGSYSSHISSKKC CCCCCCCCCCCCCCE	19.33	30576142
329	Phosphorylation	SGSYSSHISSKKCIG CCCCCCCCCCCCEEE	5.55	32142685
330	Phosphorylation	GSYSSHISSKKCIGL CCCCCCCCCCCEEEE	30.59	-
331	Phosphorylation	SYSSHISSKKCIGLI CCCCCCCCCCEEEEE	35.22	-
336	Phosphorylation	ISSKKCIGLISVNGR CCCCCEEEEEEECCE	26.82	32142685
348	Acetylation	NGRMRNNIKTGSSPN CCEECCCCCCCCCCC	4.89	19608861
350	Phosphorylation	RMRNNIKTGSSPNSV EECCCCCCCCCCCCC	38.20	23401153
352	Phosphorylation	RNNIKTGSSPNSVSS CCCCCCCCCCCCCCC	48.10	23401153
353	Acetylation	NNIKTGSSPNSVSSS CCCCCCCCCCCCCCC	29.46	19608861
353	Phosphorylation	NNIKTGSSPNSVSSS CCCCCCCCCCCCCCC	29.46	25159151
356	Phosphorylation	KTGSSPNSVSSSPTN CCCCCCCCCCCCCCC	27.10	22617229
358	Phosphorylation	GSSPNSVSSSPTNSA CCCCCCCCCCCCCHH	25.56	23911959
359	Phosphorylation	SSPNSVSSSPTNSAI CCCCCCCCCCCCHHH	37.88	22617229
360	Phosphorylation	SPNSVSSSPTNSAIT CCCCCCCCCCCHHHH	28.39	25159151
362	Phosphorylation	NSVSSSPTNSAITQL CCCCCCCCCHHHHHH	43.69	22115753
364	Phosphorylation	VSSSPTNSAITQLRN CCCCCCCHHHHHHHH	24.43	22115753
367	Phosphorylation	SPTNSAITQLRNKLE CCCCHHHHHHHHHHH	22.67	23403867
372	Acetylation	AITQLRNKLENGKPL HHHHHHHHHHCCCCC	51.23	26051181
377	Acetylation	RNKLENGKPLSMSEQ HHHHHCCCCCCHHHH	55.13	19608861
391	Sumoylation	QTGLLKIKTEPLDFN HCCCEEEECCCCCCC	45.29	-
391	Sumoylation	QTGLLKIKTEPLDFN HCCCEEEECCCCCCC	45.29	28112733
410	Phosphorylation	LMATHGFSGTSPFMN EEECCCCCCCCCCCC	45.83	-
431	Phosphorylation	SPLGVHPSAQSPMQH CCCCCCCCCCCCHHH	24.86	-
470	Phosphorylation	VLQIVDNTVSRQKMD HHHHHHCCCCHHHCC	18.52	-
479	Sumoylation	SRQKMDCKAEEISKL CHHHCCCCHHHHHHH	55.35	28112733
496	Phosphorylation	YHMKDPCSQPEEQGV CCCCCCCCCCHHCCC	54.91	25850435
504	Phosphorylation	QPEEQGVTSPNIPPV CCHHCCCCCCCCCCC	45.34	26657352
505	Phosphorylation	PEEQGVTSPNIPPVG CHHCCCCCCCCCCCC	17.34	27251275
520	Ubiquitination	LPVVSHNGATKSIID CCEECCCCCCHHHHH	29.24	21890473
555	Sumoylation	RRQISNIKKEKLRTL HHHHHHHCHHHHHHH	60.16	28112733
587	Ubiquitination	PFSCQFCKESFPGPI CCCCCCCHHCCCCCC	58.65	30230243
608	Ubiquitination	RYLCKMNEEIKAVLQ HHHHHCCHHHHHHHC	58.56	21890473
611	Sumoylation	CKMNEEIKAVLQPHE HHCCHHHHHHHCCCC	35.40	28112733
611	Ubiquitination	CKMNEEIKAVLQPHE HHCCHHHHHHHCCCC	35.40	30230243
623	Phosphorylation	PHENIVPNKAGVFVD CCCCCCCCCCCEEEC	35.60	32142685
625	Ubiquitination	ENIVPNKAGVFVDNK CCCCCCCCCEEECCH	26.48	21890473
632	Sumoylation	AGVFVDNKALLLSSV CCEEECCHHHHHHHH	35.63	28112733
632	Ubiquitination	AGVFVDNKALLLSSV CCEEECCHHHHHHHH	35.63	32015554
637	Phosphorylation	DNKALLLSSVLSEKG CCHHHHHHHHHHHCC	20.54	27732954
638	Phosphorylation	NKALLLSSVLSEKGM CHHHHHHHHHHHCCC	27.35	27732954
641	Phosphorylation	LLLSSVLSEKGMTSP HHHHHHHHHCCCCCC	34.80	29255136
646	Phosphorylation	VLSEKGMTSPINPYK HHHHCCCCCCCCCCH	39.77	22199227
647	Phosphorylation	LSEKGMTSPINPYKD HHHCCCCCCCCCCHH	18.19	23401153
672	Ubiquitination	MNMEPNSDELLKISI CCCCCCHHHHHHHHH	58.15	21890473
672	Ubiquitination	MNMEPNSDELLKISI CCCCCCHHHHHHHHH	58.15	21890473
679	Phosphorylation	DELLKISIAVGLPQE HHHHHHHHHHCCCHH	4.02	32142685
681	Phosphorylation	LLKISIAVGLPQEFV HHHHHHHHCCCHHHH	8.46	32142685
689	Ubiquitination	GLPQEFVKEWFEQRK CCCHHHHHHHHHHHC	55.32	32142685
698	Phosphorylation	WFEQRKVYQYSNSRS HHHHHCHHHCCCCCC	12.55	23403867
700	Phosphorylation	EQRKVYQYSNSRSPS HHHCHHHCCCCCCCC	7.67	23403867
701	Phosphorylation	QRKVYQYSNSRSPSL HHCHHHCCCCCCCCC	16.89	23403867
703	Phosphorylation	KVYQYSNSRSPSLER CHHHCCCCCCCCCCC	28.35	23401153
705	Phosphorylation	YQYSNSRSPSLERSS HHCCCCCCCCCCCCC	20.75	23401153
707	Phosphorylation	YSNSRSPSLERSSKP CCCCCCCCCCCCCCC	44.07	22167270
712	Phosphorylation	SPSLERSSKPLAPNS CCCCCCCCCCCCCCC	44.51	24719451
713	Sumoylation	PSLERSSKPLAPNSN CCCCCCCCCCCCCCC	45.34	28112733
713	Ubiquitination	PSLERSSKPLAPNSN CCCCCCCCCCCCCCC	45.34	32142685
726	Phosphorylation	SNPPTKDSLLPRSPV CCCCCCCCCCCCCCC	33.10	27251275
731	Phosphorylation	KDSLLPRSPVKPMDS CCCCCCCCCCCCCCC	31.91	23401153
738	Phosphorylation	SPVKPMDSITSPSIA CCCCCCCCCCCCHHH	22.86	29255136
740	Phosphorylation	VKPMDSITSPSIAEL CCCCCCCCCCHHHHH	38.24	29255136
741	Phosphorylation	KPMDSITSPSIAELH CCCCCCCCCHHHHHH	18.25	29255136
743	Phosphorylation	MDSITSPSIAELHNS CCCCCCCHHHHHHHH	33.91	29255136
750	Phosphorylation	SIAELHNSVTNCDPP HHHHHHHHHCCCCCC	21.41	27080861
752	Phosphorylation	AELHNSVTNCDPPLR HHHHHHHCCCCCCCC	29.92	27080861
760	Phosphorylation	NCDPPLRLTKPSHFT CCCCCCCCCCCCCCC	10.73	32142685
778	Phosphorylation	PVEKLDHSRSNTPSP CHHHCCCCCCCCCCC	36.75	22617229
780	Phosphorylation	EKLDHSRSNTPSPLN HHCCCCCCCCCCCCC	48.33	23401153
782	Phosphorylation	LDHSRSNTPSPLNLS CCCCCCCCCCCCCCC	26.79	23401153
784	Phosphorylation	HSRSNTPSPLNLSST CCCCCCCCCCCCCCC	39.73	23401153
789	Phosphorylation	TPSPLNLSSTSSKNS CCCCCCCCCCCCCCC	30.42	28450419
790	Phosphorylation	PSPLNLSSTSSKNSH CCCCCCCCCCCCCCC	35.16	28450419
791	Phosphorylation	SPLNLSSTSSKNSHS CCCCCCCCCCCCCCC	33.37	27486199
792	Phosphorylation	PLNLSSTSSKNSHSS CCCCCCCCCCCCCCC	41.06	27486199
793	Phosphorylation	LNLSSTSSKNSHSSS CCCCCCCCCCCCCCC	35.62	27486199
796	Phosphorylation	SSTSSKNSHSSSYTP CCCCCCCCCCCCCCC	28.60	28450419
798	Phosphorylation	TSSKNSHSSSYTPNS CCCCCCCCCCCCCCC	22.32	27486199
799	Phosphorylation	SSKNSHSSSYTPNSF CCCCCCCCCCCCCCC	23.18	27486199
800	Phosphorylation	SKNSHSSSYTPNSFS CCCCCCCCCCCCCCC	35.72	27486199
801	Phosphorylation	KNSHSSSYTPNSFSS CCCCCCCCCCCCCCC	28.32	27486199
802	Phosphorylation	NSHSSSYTPNSFSSE CCCCCCCCCCCCCCH	20.24	23401153
805	Phosphorylation	SSSYTPNSFSSEELQ CCCCCCCCCCCHHHH	27.92	28450419
807	Phosphorylation	SYTPNSFSSEELQAE CCCCCCCCCHHHHCC	36.34	27486199
808	Phosphorylation	YTPNSFSSEELQAEP CCCCCCCCHHHHCCC	32.83	27486199
819	Phosphorylation	QAEPLDLSLPKQMKE HCCCCCCCCCHHHCC	42.14	28450419
829	Phosphorylation	KQMKEPKSIIATKNK HHHCCCCCEEEECCC	29.91	-
837	Phosphorylation	IIATKNKTKASSISL EEEECCCCCCCCCCC	41.03	-
840	Phosphorylation	TKNKTKASSISLDHN ECCCCCCCCCCCCCC	29.75	28450419
841	Phosphorylation	KNKTKASSISLDHNS CCCCCCCCCCCCCCC	22.51	28450419
843	Phosphorylation	KTKASSISLDHNSVS CCCCCCCCCCCCCCC	29.68	28450419
848	Phosphorylation	SISLDHNSVSSSSEN CCCCCCCCCCCCCCC	21.69	28450419
850	Phosphorylation	SLDHNSVSSSSENSD CCCCCCCCCCCCCCC	25.07	28450419
853	Phosphorylation	HNSVSSSSENSDEPL CCCCCCCCCCCCCCC	42.62	18669648
866	Sumoylation	PLNLTFIKKEFSNSN CCCEEEEEHHHCCCC	41.90	-
866	Sumoylation	PLNLTFIKKEFSNSN CCCEEEEEHHHCCCC	41.90	28112733
885	Phosphorylation	KSTNPVFSMNPFSAK CCCCCCCCCCCCCCC	20.20	22210691
1012	Phosphorylation	DKTFQKSSSLLRHKY HHHHHHCHHHHHHHH	31.85	24719451
1013	Phosphorylation	KTFQKSSSLLRHKYE HHHHHCHHHHHHHHC	38.21	24719451
1050	Phosphorylation	IEHSRLHSGEKPYQC HHHCCCCCCCCCCCC	53.92	27732954
1055	Phosphorylation	LHSGEKPYQCDKCGK CCCCCCCCCCCCCCC	32.61	27732954
1065	Phosphorylation	DKCGKRFSHSGSYSQ CCCCCCCCCCCCHHH	22.30	25262027
1067	Phosphorylation	CGKRFSHSGSYSQHM CCCCCCCCCCHHHHH	28.39	25262027
1069	Phosphorylation	KRFSHSGSYSQHMNH CCCCCCCCHHHHHHH	25.32	25262027
1070	Phosphorylation	RFSHSGSYSQHMNHR CCCCCCCHHHHHHHH	18.84	25262027
1071	Phosphorylation	FSHSGSYSQHMNHRY CCCCCCHHHHHHHHH	18.46	25262027
1097	Phosphorylation	AAEREAREKGHLEPT HHHHHHHHCCCCCHH	71.13	32142685
1112	Phosphorylation	ELLMNRAYLQSITPQ HHHHCHHHHHHCCCC	11.31	30301811
1115	Phosphorylation	MNRAYLQSITPQGYS HCHHHHHHCCCCCCC	26.32	29255136
1117	Phosphorylation	RAYLQSITPQGYSDS HHHHHHCCCCCCCCH	18.14	29255136
1121	Phosphorylation	QSITPQGYSDSEERE HHCCCCCCCCHHHHH	12.21	28450419
1122	Phosphorylation	SITPQGYSDSEERES HCCCCCCCCHHHHHC	41.29	23401153
1124	Phosphorylation	TPQGYSDSEERESMP CCCCCCCHHHHHCCC	35.10	29255136
1129	Phosphorylation	SDSEERESMPRDGES CCHHHHHCCCCCCCC	40.06	28450419
1136	Phosphorylation	SMPRDGESEKEHEKE CCCCCCCCHHHHHHC	60.54	23401153
1167	Phosphorylation	FEEEEEESENKSMDT HHHHHHHHHHCCCCC	50.15	25159151
1178	Phosphorylation	SMDTDPETIRDEEET CCCCCHHHHCCHHHH	27.05	24719451
1185	Phosphorylation	TIRDEEETGDHSMDD HHCCHHHHCCCCCCC	51.71	-
1189	Phosphorylation	EEETGDHSMDDSSED HHHHCCCCCCCCCCC	28.75	-
1193	Phosphorylation	GDHSMDDSSEDGKME CCCCCCCCCCCCCCC	31.22	-
1194	Phosphorylation	DHSMDDSSEDGKMET CCCCCCCCCCCCCCC	46.86	-
1201	Phosphorylation	SEDGKMETKSDHEED CCCCCCCCCCCCCHH	32.14	29514088
1203	Phosphorylation	DGKMETKSDHEEDNM CCCCCCCCCCCHHCC	52.17	23401153

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
-	K	Ubiquitination	E3 ubiquitin ligase	FBXW7	Q969H0	PMID:30783098
-	K	Ubiquitination	E3 ubiquitin ligase	FBXO45	P0C2W1	PMID:25460509
-	K	Ubiquitination	E3 ubiquitin ligase	X	P03165	PMID:32235678

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Reference
391	K	Sumoylation	16061479
Sumoylation on Lys-391 and Lys-866 is promoted by the E3 SUMO-protein ligase CBX4, and impairs interaction with CTBP1 and transcription repression activity.
866	K	Sumoylation	16061479
Sumoylation on Lys-391 and Lys-866 is promoted by the E3 SUMO-protein ligase CBX4, and impairs interaction with CTBP1 and transcription repression activity.

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of ZEB2_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
CSN6_HUMAN	COPS6	physical	16169070
MTA1_HUMAN	MTA1	physical	18182442
MTA2_HUMAN	MTA2	physical	18182442
HDAC1_HUMAN	HDAC1	physical	18182442
HDAC2_HUMAN	HDAC2	physical	18182442
RBBP4_HUMAN	RBBP4	physical	18182442
RBBP7_HUMAN	RBBP7	physical	18182442
CTBP1_HUMAN	CTBP1	physical	16061479
HDAC4_HUMAN	HDAC4	physical	16061479
CBX4_HUMAN	CBX4	physical	16061479
SMAD3_HUMAN	SMAD3	physical	16061479
A4_HUMAN	APP	physical	21832049
SMAD1_HUMAN	SMAD1	physical	22365546

Drug and Disease Associations

Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
235730	Mowat-Wilson syndrome (MOWS)
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of ZEB2_HUMAN

Related Literatures of Post-Translational Modification

Acetylation
Reference	PubMed
"Lysine acetylation targets protein complexes and co-regulates majorcellular functions."; Choudhary C., Kumar C., Gnad F., Nielsen M.L., Rehman M., Walther T.,Olsen J.V., Mann M.; Science 325:834-840(2009). Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-377, AND MASS SPECTROMETRY.	19608861 [Abstract]
Phosphorylation
Reference	PubMed
"Lys-N and trypsin cover complementary parts of the phosphoproteome ina refined SCX-based approach."; Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J.,Mohammed S.; Anal. Chem. 81:4493-4501(2009). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-782 AND SER-784, ANDMASS SPECTROMETRY.	19413330 [Abstract]
Sumoylation
Reference	PubMed
"Pc2-mediated sumoylation of Smad-interacting protein 1 attenuatestranscriptional repression of E-cadherin."; Long J., Zuo D., Park M.; J. Biol. Chem. 280:35477-35489(2005). Cited for: FUNCTION, SUMOYLATION AT LYS-391 AND LYS-866, INTERACTION WITH CBX4AND CTBP1, AND SUBCELLULAR LOCATION.	16061479 [Abstract]

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