Y4374_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: Y4374_ARATH
• UniProt AC: Q9SUQ3
• Protein Name: Probable inactive receptor kinase At4g23740
• Gene Name: At4g23740
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 638
• Subcellular Localization: Membrane ; Single-pass membrane protein .
• Protein Sequence: MEALRIYLWSLCLSLCLIIYGANSDPLEDKRALLEFLTIMQPTRSLNWNETSQVCNIWTGVTCNQDGSRIIAVRLPGVGLNGQIPPNTISRLSALRVLSLRSNLISGEFPKDFVELKDLAFLYLQDNNLSGPLPLDFSVWKNLTSVNLSNNGFNGTIPSSLSRLKRIQSLNLANNTLSGDIPDLSVLSSLQHIDLSNNYDLAGPIPDWLRRFPFSSYTGIDIIPPGGNYTLVTPPPPSEQTHQKPSKARFLGLSETVFLLIVIAVSIVVITALAFVLTVCYVRRKLRRGDGVISDNKLQKKGGMSPEKFVSRMEDVNNRLSFFEGCNYSFDLEDLLRASAEVLGKGTFGTTYKAVLEDATSVAVKRLKDVAAGKRDFEQQMEIIGGIKHENVVELKAYYYSKDEKLMVYDYFSRGSVASLLHGNRGENRIPLDWETRMKIAIGAAKGIARIHKENNGKLVHGNIKSSNIFLNSESNGCVSDLGLTAVMSPLAPPISRQAGYRAPEVTDTRKSSQLSDVYSFGVVLLELLTGKSPIHTTAGDEIIHLVRWVHSVVREEWTAEVFDIELLRYTNIEEEMVEMLQIAMSCVVKAADQRPKMSDLVRLIENVGNRRTSIEPEPELKPKSENGASETSTPSEI

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
305	Phosphorylation	LQKKGGMSPEKFVSR CHHCCCCCHHHHHHH	32.93	26476206
339	Phosphorylation	LEDLLRASAEVLGKG HHHHHHHHHHHHCCC	20.66	19880383
360	Phosphorylation	KAVLEDATSVAVKRL HHHHCHHHHHHHHHH	35.74	-
416	Phosphorylation	YDYFSRGSVASLLHG EEECCCCCHHHHHCC	17.25	-
419	Phosphorylation	FSRGSVASLLHGNRG CCCCCHHHHHCCCCC	29.34	-
436	Phosphorylation	RIPLDWETRMKIAIG CCCCCHHHHHHHHHH	31.63	-
509	Phosphorylation	RAPEVTDTRKSSQLS CCCCCCCCCCCCCHH	30.54	-
513	Phosphorylation	VTDTRKSSQLSDVYS CCCCCCCCCHHHHHH	37.87	-
559	Phosphorylation	SVVREEWTAEVFDIE HHHCHHHHHHEEEEE	19.07	23111157

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of Y4374_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of Y4374_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of Y4374_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
SUB_ARATH	SUB	physical	21423366
AMT12_ARATH	AMT1;2	physical	21423366
Y3804_ARATH	AT3G28040	physical	21423366
Y5639_ARATH	AT5G63930	physical	21423366
PXC3_ARATH	AT2G41820	physical	21423366
MLO2_ARATH	MLO2	physical	21423366
TET11_ARATH	TET11	physical	21423366
HHP2_ARATH	HHP2	physical	24833385
UBC34_ARATH	UBC34	physical	24833385
CP21D_ARATH	AT3G66654	physical	24833385
SD18_ARATH	RK3	physical	24833385
PAM74_ARATH	AT5G59650	physical	24833385
BETL2_ARATH	AT1G29060	physical	24833385

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Phosphorylation

"Large-scale Arabidopsis phosphoproteome profiling reveals novelchloroplast kinase substrates and phosphorylation networks.";
Reiland S., Messerli G., Baerenfaller K., Gerrits B., Endler A.,Grossmann J., Gruissem W., Baginsky S.;
Plant Physiol. 150:889-903(2009).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-305, AND MASSSPECTROMETRY.
PubMed: 19376835

"Temporal analysis of sucrose-induced phosphorylation changes inplasma membrane proteins of Arabidopsis.";
Niittylae T., Fuglsang A.T., Palmgren M.G., Frommer W.B.,Schulze W.X.;
Mol. Cell. Proteomics 6:1711-1726(2007).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-339, AND MASSSPECTROMETRY.
PubMed: 17586839