dbPTM

WDR82_DROME - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	WDR82_DROME
UniProt AC	Q9VLN1
Protein Name	WD repeat-containing protein 82 {ECO:0000250\|UniProtKB:Q6UXN9}
Gene Name	Wdr82 {ECO:0000312\|EMBL:AAF52654.1, ECO:0000312\|FlyBase:FBgn0032030}
Organism	Drosophila melanogaster (Fruit fly).
Sequence Length	317
Subcellular Localization	Nucleus .
Protein Description	Component of the SET1 complex that specifically di- and trimethylates 'Lys-4' of histone H3..
Protein Sequence	MKIKLIDSVVRSFKVAKIFRENTDKINAIDFAPNGEHLISCSEDDQIVIYDCEKGTQSRTVNSKKYGVDLIHFTHANNTAIHSSTKVDDTIRYLSLHDNKYLRYFPGHTKKVISLCISPVEDTFLSGSLDKTLRLWDLRSPNCQGLMHLSGRPIAAYDPEGLIFAAGVNSESIKLYDLRSFDKGPFVTFKLNQEKECDWTGLKFSRDGKTILISTNGSVIRLVDAFHGTPLQTFTGYPNNKGIPIEASFSPDSQFIFSGSTDGRVHIWNADTGNKVSVLNGDHPGPVQCVQFNPKYMMLASACTNMAFWLPTSEEGL

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	Reference
4	Acetylation	----MKIKLIDSVVR ----CCCEEHHHHHH	21791702
17	Acetylation	VRSFKVAKIFRENTD HHHHHHHHHHHCCCC	19608861
250	Phosphorylation	IPIEASFSPDSQFIF CCCEEEECCCCCEEE	22817900

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of WDR82_DROME !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of WDR82_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of WDR82_DROME !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
SUS_DROME	su(s)	physical	14605208
GMPPB_DROME	CG1129	physical	22036573
HPF1_DROME	CG1218	physical	22036573
THIO2_DROME	Trx-2	physical	22036573
SUS_DROME	su(s)	physical	26577379
CXXC1_DROME	Cfp1	physical	21875999
SET1_DROME	Set1	physical	21875999
DPY30_DROME	Dpy-30L1	physical	21875999
RBBP5_DROME	Rbbp5	physical	21875999
ASH2_DROME	ash2	physical	21875999
HCF_DROME	Hcf	physical	21875999
WDS_DROME	wds	physical	21875999

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of WDR82_DROME

Related Literatures of Post-Translational Modification