DPY30_DROME - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: DPY30_DROME
• UniProt AC: Q9VKQ9
• Protein Name: Protein dpy-30 homolog {ECO:0000250|UniProtKB:Q9C005}
• Gene Name: Dpy-30L1 {ECO:0000312|EMBL:AAF53001.1, ECO:0000312|FlyBase:FBgn0032293}
• Organism: Drosophila melanogaster (Fruit fly).
• Sequence Length: 134
• Subcellular Localization: Nucleus .
• Protein Description: Component of the SET1 complex that specifically di- and trimethylates 'Lys-4' of histone H3 and of the MLL3/4 complex which also methylates histone H3 'Lys-4'. Inhibits MTF-1 transcription factor activity..
• Protein Sequence: MEAKTDAPISPAPTTNPPAEAGKEPNASSNAQANPTAAPGAPPSGAIAVGQSTNPVAQQQQQPAVAKKPSSETNNMPTRQYLDQTVAPVLLHGMQALARERPTDPIQFLASYLLKHSNGCDENNASAAAVDNNS

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
5	Phosphorylation	---MEAKTDAPISPA ---CCCCCCCCCCCC		19429919
10	Phosphorylation	AKTDAPISPAPTTNP CCCCCCCCCCCCCCC		19429919
70	Phosphorylation	PAVAKKPSSETNNMP CHHHCCCCCCCCCCC		21082442

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of DPY30_DROME !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of DPY30_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of DPY30_DROME !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.