TTL3_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: TTL3_ARATH
• UniProt AC: Q9SIN1
• Protein Name: Inactive TPR repeat-containing thioredoxin TTL3
• Gene Name: TTL3
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 691
• Protein Description: Involved in osmotic and salt stress tolerance. May play a role in the control of meristematic cell size during osmotic stress. May function as an adaptor protein for BRL2 and may be required for signaling affecting leaf vascular tissue pattern formation..
• Protein Sequence: MSHSRRLSLEPAIDSITGRFRDLQRNDDDVNKPDFRELDLGSPVSTLMPRGSASSSAAATPTSSSGSSGSASGKPSVSSQMAKRLDDAYKSHSGELSSPGSGMPTTTRILKPGHRRSSSTGTPLIFSGSSFTSATSHTSPQGGGSGATSAVSPNTGVLPAGNICPSGRILKTGMASRTSSRTETLCTGTGNYGHGNVVRSGGGGGTSGKAVRVAENGENPEELKRMGNDMYRRGSFSEALSLYDRAILISPGNAAYRSNRAAALTALRRLGEAVKECLEAVRIDPSYSRAHQRLASLYLRLGEAENARRHICFSGQCPDQADLQRLQTLEKHLRRCWEARKIGDWKTAIKETDAAIANGADSSPQLVACKAEAFLRLKQIEDSDFCVSCIPRLDHHYHSQPQVKLFGMVVEAYVLCIQAQVDMALGRFENAVVKAERAAMLDQTNPEVVSVLNNVKMVVRARTRGNELFSSGRFSEACVAYGDGLKQDDSNSVLYCNRAACWYKLGLWEKSVEDCNHALKSQPSYIKALLRRAASYGKLGRWEDAVKDYEFLRRELPGDSEVAESLERAKTVLMNRSQESKSLGFNNEVEAVSTLDKFKKSVALPGVSVFHFKSSSNRQCEEISPFINTLCLRYPLVHFFMVDVEESMALAKAESIRKVPTFKMYKNGDKVKEMVCPSHQFLEDSIKHFLL

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
8	Phosphorylation	MSHSRRLSLEPAIDS CCCCCCCCCHHHHHH	28.95	30291188
42	Phosphorylation	FRELDLGSPVSTLMP HHHCCCCCCHHHHCC	29.44	30291188
45	Phosphorylation	LDLGSPVSTLMPRGS CCCCCCHHHHCCCCC	21.14	23776212
91	Phosphorylation	RLDDAYKSHSGELSS HHHHHHHHCCCCCCC	15.37	25561503
93	Phosphorylation	DDAYKSHSGELSSPG HHHHHHCCCCCCCCC	40.84	23111157
97	Phosphorylation	KSHSGELSSPGSGMP HHCCCCCCCCCCCCC	30.13	25561503
98	Phosphorylation	SHSGELSSPGSGMPT HCCCCCCCCCCCCCC	46.00	25561503
119	Phosphorylation	PGHRRSSSTGTPLIF CCCCCCCCCCCCEEE	31.91	29654922
120	Phosphorylation	GHRRSSSTGTPLIFS CCCCCCCCCCCEEEE	47.20	29654922
179	Phosphorylation	TGMASRTSSRTETLC CCCCCCCCCCCEEEE	19.40	25561503
180	Phosphorylation	GMASRTSSRTETLCT CCCCCCCCCCEEEEC	42.48	25561503
182	Phosphorylation	ASRTSSRTETLCTGT CCCCCCCCEEEECCC	34.96	25561503
258	Phosphorylation	PGNAAYRSNRAAALT CCCHHHHHHHHHHHH	20.28	19880383
577	Phosphorylation	KTVLMNRSQESKSLG HHHHHCCCHHHHHCC	33.04	24894044

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of TTL3_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of TTL3_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of TTL3_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
SAP1_ARATH	AT1G12440	physical	19000166
ACCO2_ARATH	ACO2	physical	19000166
SKI15_ARATH	AT1G76920	physical	19000166
CML35_ARATH	AT2G41410	physical	19000166
UBP25_ARATH	UBP25	physical	19000166
TCTP1_ARATH	TCTP	physical	19000166
RB47A_ARATH	RBP47A	physical	19000166
RL63_ARATH	AT1G74050	physical	19000166
TLC1_ARATH	NTT1	physical	19000166
RPT2_ARATH	RPT2	physical	19000166
R18A2_ARATH	AT2G34480	physical	19000166
RAP23_ARATH	EBP	physical	19000166
ATP5H_ARATH	ATPQ	physical	19000166
MAOP2_ARATH	NADP-ME2	physical	19000166
CB1C_ARATH	CAB1	physical	19000166
G3PB_ARATH	GAPB	physical	19000166
ZDHC1_ARATH	AT1G69420	physical	19000166
GASA1_ARATH	GASA1	physical	19000166
SAP5_ARATH	AT3G12630	physical	19000166
R13A2_ARATH	AT3G24830	physical	19000166
XTH15_ARATH	XTH15	physical	19000166
ACFR1_ARATH	ACYB-2	physical	19000166
CRR60_ARATH	PDLP7	physical	19000166

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.