ATP5H_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ATP5H_ARATH
• UniProt AC: Q9FT52
• Protein Name: ATP synthase subunit d, mitochondrial
• Gene Name: At3g52300
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 168
• Subcellular Localization: Mitochondrion. Mitochondrion inner membrane.
• Protein Description: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements (By similarity)..
• Protein Sequence: MSGAGKKIADVAFKASRTIDWDGMAKVLVTDEARREFSNLRRAFDEVNTQLQTKFSQEPEPIDWDYYRKGIGAGIVDKYKEAYDSIEIPKYVDKVTPEYKPKFDALLVELKEAEQKSLKESERLEKEIADVQEISKKLSTMTADEYFEKHPELKKKFDDEIRNDNWGY

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
90	Acetylation	YDSIEIPKYVDKVTP HHHCCCCHHHCCCCC	64.66	24727099
94	Acetylation	EIPKYVDKVTPEYKP CCCHHHCCCCCCCCC	37.65	24727099
96	Phosphorylation	PKYVDKVTPEYKPKF CHHHCCCCCCCCCCC	19.02	22092075
102	Acetylation	VTPEYKPKFDALLVE CCCCCCCCCCHHHHH	52.29	24727099
111	Acetylation	DALLVELKEAEQKSL CHHHHHHHHHHHHCH	41.18	24727099
116	Acetylation	ELKEAEQKSLKESER HHHHHHHHCHHHHHH	49.62	24727099
149	Acetylation	TADEYFEKHPELKKK CHHHHHHHCHHHHHH	55.34	24727099
156	Acetylation	KHPELKKKFDDEIRN HCHHHHHHHCHHHHC	53.06	24727099

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ATP5H_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ATP5H_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ATP5H_ARATH !!

Protein-Protein Interaction

Oops, there are no PPI records of ATP5H_ARATH !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.