MAOP2_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: MAOP2_ARATH
• UniProt AC: Q9LYG3
• Protein Name: NADP-dependent malic enzyme 2
• Gene Name: NADP-ME2
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 588
• Subcellular Localization: Cytoplasm .
• Protein Sequence: MGSTPTDLPGEDVADNRSGVGGGISDVYGEDSATLDQLVTPWVTSVASGYTLMRDPRYNKGLAFTDKERDAHYLTGLLPPVILSQDVQERKVMHNLRQYTVPLQRYMALMDLQERNERLFYKLLIDNVEELLPVVYTPTVGEACQKYGSIFRKPQGLYISLNEKGKILEVLKNWPQRGIQVIVVTDGERILGLGDLGCQGMGIPVGKLSLYTALGGIRPSACLPITIDVGTNNEKLLNDEFYIGLKQRRATGQEYAEFLHEFMCAVKQNYGEKVLVQFEDFANHNAFDLLSKYSDSHLVFNDDIQGTASVVLAGLIAAQKVLGKKLADHTFLFLGAGEAGTGIAELIALKISKETGAPITETRKKIWLVDSKGLIVSSRKESLQHFKQPWAHEHKPVKDLIGAVNAIKPTVLIGTSGVGQTFTKEVVEAMATNNEKPLILALSNPTSQAECTAEQAYTWTKGRAIFGSGSPFDPVVYDGKTYLPGQANNCYIFPGLGLGLIMSGAIRVRDDMLLAASEALAAQVTEEHYANGLIYPPFSNIREISANIAACVAAKTYDLGLASNLPRAKDLVKFAESSMYSPVYRNYR

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Acetylation	------MGSTPTDLP ------CCCCCCCCC		22223895
3	Phosphorylation	-----MGSTPTDLPG -----CCCCCCCCCC		19376835
4	Phosphorylation	----MGSTPTDLPGE ----CCCCCCCCCCC		19376835
6	Phosphorylation	--MGSTPTDLPGEDV --CCCCCCCCCCCCC		19376835
99	Phosphorylation	VMHNLRQYTVPLQRY HHHHHHHCHHHHHHH		19880383
100	Phosphorylation	MHNLRQYTVPLQRYM HHHHHHCHHHHHHHH		19880383
136	Phosphorylation	EELLPVVYTPTVGEA HHHCCEEECCCHHHH		25368622
137	Phosphorylation	ELLPVVYTPTVGEAC HHCCEEECCCHHHHH		25368622
139	Phosphorylation	LPVVYTPTVGEACQK CCEEECCCHHHHHHH		25368622
147	Phosphorylation	VGEACQKYGSIFRKP HHHHHHHHHCCCCCC		25368622
149	Phosphorylation	EACQKYGSIFRKPQG HHHHHHHCCCCCCCC		25368622
371	Phosphorylation	KKIWLVDSKGLIVSS CEEEEECCCCEEEEC		30291188
539	Phosphorylation	GLIYPPFSNIREISA CCCCCCCCCHHHHHH		28011693
578	Phosphorylation	LVKFAESSMYSPVYR HHHHHHHHCCCCCCC		30407730
580	Phosphorylation	KFAESSMYSPVYRNY HHHHHHCCCCCCCCC		19880383
581	Phosphorylation	FAESSMYSPVYRNYR HHHHHCCCCCCCCCC		19880383
584	Phosphorylation	SSMYSPVYRNYR--- HHCCCCCCCCCC---		30407730

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of MAOP2_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of MAOP2_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of MAOP2_ARATH !!

Protein-Protein Interaction

Oops, there are no PPI records of MAOP2_ARATH !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.