TRABD_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: TRABD_HUMAN
• UniProt AC: Q9H4I3
• Protein Name: TraB domain-containing protein
• Gene Name: TRABD
• Organism: Homo sapiens (Human).
• Sequence Length: 376
• Protein Sequence: MDGEEQQPPHEANVEPVVPSEASEPVPRVLSGDPQNLSDVDAFNLLLEMKLKRRRQRPNLPRTVTQLVAEDGSRVYVVGTAHFSDDSKRDVVKTIREVQPDVVVVELCQYRVSMLKMDESTLLREAQELSLEKLQQAVRQNGLMSGLMQMLLLKVSAHITEQLGMAPGGEFREAFKEASKVPFCKFHLGDRPIPVTFKRAIAALSFWQKVRLAWGLCFLSDPISKDDVERCKQKDLLEQMMAEMIGEFPDLHRTIVSERDVYLTYMLRQAARRLELPRASDAEPRKCVPSVVVGVVGMGHVPGIEKNWSTDLNIQEIMTVPPPSVSGRVSRLAVKAAFFGLLGYSLYWMGRRTASLVLSLPAAQYCLQRVTEARHK

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
1	Acetylation	-------MDGEEQQP -------CCCCCCCC	15.67	22814378
42 (in isoform 2)	Ubiquitination	-	8.62	21906983
47 (in isoform 2)	Ubiquitination	-	7.33	21906983
50	Ubiquitination	FNLLLEMKLKRRRQR HHHHHHHHHHHHCCC	41.29	21906983
50 (in isoform 1)	Ubiquitination	-	41.29	21906983
52	Ubiquitination	LLLEMKLKRRRQRPN HHHHHHHHHHCCCCC	38.04	-
65	Phosphorylation	PNLPRTVTQLVAEDG CCCCCCHHHHHHCCC	18.64	23186163
70 (in isoform 2)	Ubiquitination	-	56.26	21906983
87 (in isoform 2)	Ubiquitination	-	34.28	21906983
88 (in isoform 1)	Ubiquitination	-	60.66	21906983
88	Ubiquitination	AHFSDDSKRDVVKTI EECCCCCCCHHHHHH	60.66	21906983
93	Ubiquitination	DSKRDVVKTIREVQP CCCCHHHHHHHHHCC	37.78	21906983
93 (in isoform 1)	Ubiquitination	-	37.78	21906983
94	Phosphorylation	SKRDVVKTIREVQPD CCCHHHHHHHHHCCC	17.41	27251275
110	Phosphorylation	VVVELCQYRVSMLKM EEEEECHHHHHHHCC	16.40	24719451
113	Phosphorylation	ELCQYRVSMLKMDES EECHHHHHHHCCCHH	14.92	24114839
116 (in isoform 1)	Ubiquitination	-	35.35	21906983
116	Ubiquitination	QYRVSMLKMDESTLL HHHHHHHCCCHHHHH	35.35	21906983
120	Phosphorylation	SMLKMDESTLLREAQ HHHCCCHHHHHHHHH	21.79	21815630
121	Phosphorylation	MLKMDESTLLREAQE HHCCCHHHHHHHHHH	27.97	24114839
130 (in isoform 2)	Ubiquitination	-	33.46	-
133 (in isoform 1)	Ubiquitination	-	57.81	21906983
133	Ubiquitination	AQELSLEKLQQAVRQ HHHHCHHHHHHHHHH	57.81	21906983
176	Ubiquitination	GEFREAFKEASKVPF HHHHHHHHHHHCCCC	60.46	-
179 (in isoform 2)	Ubiquitination	-	34.97	21906983
180	Ubiquitination	EAFKEASKVPFCKFH HHHHHHHCCCCCEEE	62.06	-
185	Ubiquitination	ASKVPFCKFHLGDRP HHCCCCCEEECCCCC	35.88	-
198	Ubiquitination	RPIPVTFKRAIAALS CCCCCHHHHHHHHHH	31.39	-
209	Ubiquitination	AALSFWQKVRLAWGL HHHHHHHHHHHHHHH	21.66	-
225 (in isoform 1)	Ubiquitination	-	59.68	21906983
225	Ubiquitination	FLSDPISKDDVERCK HHCCCCCHHHHHHHH	59.68	2190698
232	Ubiquitination	KDDVERCKQKDLLEQ HHHHHHHHHHHHHHH	67.61	-
264	Phosphorylation	SERDVYLTYMLRQAA CHHHHHHHHHHHHHH	6.81	27174698
280	Phosphorylation	RLELPRASDAEPRKC HCCCCCCCCCCCCCC	38.34	28555341
286	Ubiquitination	ASDAEPRKCVPSVVV CCCCCCCCCCCEEEE	50.75	-
309	Phosphorylation	PGIEKNWSTDLNIQE CCCCCCCCCCCCHHH	22.80	-
310	Phosphorylation	GIEKNWSTDLNIQEI CCCCCCCCCCCHHHE	35.80	-
319	Phosphorylation	LNIQEIMTVPPPSVS CCHHHEECCCCCCCC	35.21	-
345	Phosphorylation	FFGLLGYSLYWMGRR HHHHHHHHHHHCCHH	17.12	24719451
347	Phosphorylation	GLLGYSLYWMGRRTA HHHHHHHHHCCHHHH	6.34	24719451

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of TRABD_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of TRABD_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of TRABD_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
NDKB_HUMAN	NME2	physical	26186194
AT12A_HUMAN	ATP12A	physical	26186194
AT2B2_HUMAN	ATP2B2	physical	26186194
DJC11_HUMAN	DNAJC11	physical	26186194
HSDL1_HUMAN	HSDL1	physical	26186194
TOM40_HUMAN	TOMM40	physical	26186194
BRE1B_HUMAN	RNF40	physical	26186194
QCR8_HUMAN	UQCRQ	physical	26186194
NDKB_HUMAN	NME2	physical	28514442
DJC11_HUMAN	DNAJC11	physical	28514442
HSDL1_HUMAN	HSDL1	physical	28514442
AT12A_HUMAN	ATP12A	physical	28514442
FCN1_HUMAN	FCN1	physical	28514442

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.