SKI22_ARATH - dbPTM
SKI22_ARATH - PTM Information in dbPTM
Basic Information of Protein
UniProt ID SKI22_ARATH
UniProt AC Q9ZUB8
Protein Name F-box protein SKIP22
Gene Name SKIP22
Organism Arabidopsis thaliana (Mouse-ear cress).
Sequence Length 475
Subcellular Localization Nucleus.
Protein Description Component of SCF(ASK-cullin-F-box) E3 ubiquitin ligase complexes, which may mediate the ubiquitination and subsequent proteasomal degradation of target proteins..
Protein Sequence MKLRLRHHETRETLKLELADADTLHDLRRRINPTVPSSVHLSLNRKDELITPSPEDTLRSLGLISGDLIYFSLEAGESSNWKLRDSETVASQSESNQTSVHDSIGFAEVDVVPDQAKSNPNTSVEDPEGDISGMEGPEPMDVEQLDMELAAAGSKRLSEPFFLKNILLEKSGDTSELTTLALSVHAVMLESGFVLLNHGSDKFNFSKELLTVSLRYTLPELIKSKDTNTIESVSVKFQNLGPVVVVYGTVGGSSGRVHMNLDKRRFVPVIDLVMDTSTSDEEGSSSIYREVFMFWRMVKDRLVIPLLIGICDKAGLEPPPCLMRLPTELKLKILELLPGVSIGNMACVCTEMRYLASDNDLWKQKCLEEVNNFVVTEAGDSVNWKARFATFWRQKQLAAASDTFWRQNQLGRRNISTGRSGIRFPRIIGDPPFTWFNGDRMHGSIGIHPGQSARGLGRRTWGQLFTPRCNLGGLN
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
232PhosphorylationKDTNTIESVSVKFQN
CCCCCEEEEEEEEEC
18.8128011693
234PhosphorylationTNTIESVSVKFQNLG
CCCEEEEEEEEECCC
28.9528011693

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of SKI22_ARATH !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of SKI22_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of SKI22_ARATH !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
SKP1A_ARATHSKP1physical
23166809
SKP1B_ARATHASK2physical
23166809
ASK3_ARATHSK3physical
23166809
ASK4_ARATHSK4physical
23166809
ASK11_ARATHSK11physical
23166809
ASK12_ARATHSK12physical
23166809
ASK13_ARATHSK13physical
23166809
ASK14_ARATHSK14physical
23166809

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of SKI22_ARATH

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Related Literatures of Post-Translational Modification

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