dbPTM

ASK3_ARATH - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	ASK3_ARATH
UniProt AC	Q9SL93
Protein Name	SKP1-like protein 3
Gene Name	ASK3
Organism	Arabidopsis thaliana (Mouse-ear cress).
Sequence Length	163
Subcellular Localization	Nucleus.
Protein Description	Involved in ubiquitination and subsequent proteasomal degradation of target proteins. Together with CUL1, RBX1 and a F-box protein, it forms a SCF E3 ubiquitin ligase complex. The functional specificity of this complex depends on the type of F-box protein. In the SCF complex, it serves as an adapter that links the F-box protein to CUL1 (By similarity)..
Protein Sequence	MAETKKMIILKSSDGESFEVEEAVAVESQTIKHMIEDDCVDNGIPLPNVTGAILAKVIEYCKKHVEAAAEAGGDKDFYGSTENHELKTWDNDFVKVDHPTLFDLLRAANYLNISGLLDLTCKAVADQMRGKTPAQMREHFNIKNDYTPEEEAEVRNENRWAFE

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
Oops, there are no PTM records of ASK3_ARATH !!

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of ASK3_ARATH !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of ASK3_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of ASK3_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
ADO2_ARATH	LKP2	physical	15310821
ADO3_ARATH	FKF1	physical	14749489
FBK77_ARATH	HWS	physical	14749489
FBD40_ARATH	AT4G10400	physical	21798944
FBL41_ARATH	AT3G03030	physical	21798944
TGA1_ARATH	TGA1	physical	21798944
FBL59_ARATH	AT3G58930	physical	21798944
FBK77_ARATH	HWS	physical	21798944
TIR1_ARATH	TIR1	physical	23226441
UFO_ARATH	UFO	physical	23226441

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of ASK3_ARATH

Related Literatures of Post-Translational Modification