ROGDI_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ROGDI_HUMAN
• UniProt AC: Q9GZN7
• Protein Name: Protein rogdi homolog
• Gene Name: ROGDI
• Organism: Homo sapiens (Human).
• Sequence Length: 287
• Subcellular Localization: Nucleus envelope . Cell junction, synapse, presynaptic cell membrane . Cell projection, axon . Perikaryon . Cell projection, dendrite . Cytoplasmic vesicle, secretory vesicle, synaptic vesicle . Detected primarily at presynaptic sites on axons, and t
• Protein Sequence: MATVMAATAAERAVLEEEFRWLLHDEVHAVLKQLQDILKEASLRFTLPGSGTEGPAKQENFILGSCGTDQVKGVLTLQGDALSQADVNLKMPRNNQLLHFAFREDKQWKLQQIQDARNHVSQAIYLLTSRDQSYQFKTGAEVLKLMDAVMLQLTRARNRLTTPATLTLPEIAASGLTRMFAPALPSDLLVNVYINLNKLCLTVYQLHALQPNSTKNFRPAGGAVLHSPGAMFEWGSQRLEVSHVHKVECVIPWLNDALVYFTVSLQLCQQLKDKISVFSSYWSYRPF

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Acetylation	------MATVMAATA ------CHHHHHHHH	14.65	22814378
3	O-linked_Glycosylation	-----MATVMAATAA -----CHHHHHHHHH	14.98	30379171
65	Phosphorylation	QENFILGSCGTDQVK CCCEEECCCCCCCCC	13.11	-
68	Phosphorylation	FILGSCGTDQVKGVL EEECCCCCCCCCEEE	27.82	-
76	Phosphorylation	DQVKGVLTLQGDALS CCCCEEEEECCCHHH	18.03	-
83	Phosphorylation	TLQGDALSQADVNLK EECCCHHHHCCEECC	25.66	-
128	Phosphorylation	SQAIYLLTSRDQSYQ HHHHHHHHCCCCCCC	21.08	24719451
227	Phosphorylation	AGGAVLHSPGAMFEW CCCEEEECCCCCCCC	22.37	25159151

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ROGDI_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ROGDI_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ROGDI_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
CSN6_HUMAN	COPS6	physical	16169070
CE126_HUMAN	KIAA1377	physical	16169070
AT1A2_HUMAN	ATP1A2	physical	26186194
AT2A1_HUMAN	ATP2A1	physical	26186194
DMXL1_HUMAN	DMXL1	physical	26186194
DMXL2_HUMAN	DMXL2	physical	26186194
WDR7_HUMAN	WDR7	physical	26186194
TBA3C_HUMAN	TUBA3C	physical	26186194
MYH8_HUMAN	MYH8	physical	26186194
MYH7_HUMAN	MYH7	physical	26186194
WDR7_HUMAN	WDR7	physical	28514442
DMXL1_HUMAN	DMXL1	physical	28514442
DMXL2_HUMAN	DMXL2	physical	28514442
AT1A2_HUMAN	ATP1A2	physical	28514442
MYH7_HUMAN	MYH7	physical	28514442
TBA3C_HUMAN	TUBA3C	physical	28514442
AT2A1_HUMAN	ATP2A1	physical	28514442
MYH8_HUMAN	MYH8	physical	28514442

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.