POF14_SCHPO - dbPTM
POF14_SCHPO - PTM Information in dbPTM
Basic Information of Protein
UniProt ID POF14_SCHPO
UniProt AC Q10223
Protein Name F-box protein pof14
Gene Name pof14
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length 431
Subcellular Localization Cytoplasm. Nucleus. Endoplasmic reticulum. Associated with vesicle-like and endoplasmic reticulum (excluding a nuclear rim) structures.
Protein Description Expression is induced during oxidative stress. Plays an essential, SCF-independent, role in the stress response to hydrogen peroxide for survival, by negatively regulating ergosterol synthesis via direct binding to the squalene synthase erg9..
Protein Sequence MLQFSFQNCKTHTCYMNTSVNEHLDQDESFLRILIDTRKKIRSSYFKPQTFDEFVHCLARVRAMKRLVSICSNFDEEDNWNGVWNTLVVDGDSHASAMIDYEGLLDKCSLSRNLLELINDYAEYTTQVLPFRKIPSSDNLDSSLNLTVASPKSNLYYRYSSESPKYAKILDCPDEILQLIFSYCYDASYIEKLPFAFSYRKQRHTLIHDLPNTCLRFKKILSPRNVSFWKRLLKVHKKNPNSAVTCSESINTSAVAKFTDIPTIIPIFLDPSYQSYAAKTIHSDTSSLASSIIQTGDGTQSCDESTYIELACNLVGRCVLCNRIPKLTKFKDCITSFYRPSVATNICDQCLEAIIDFYEPVSRYKFDVMKDRLGVGYISRPGQKFPSWLSEHVQLARDEEKAFKSIYHSQGEFARSLFRLFRAQLAELCEQ
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
227PhosphorylationILSPRNVSFWKRLLK
HCCCCCHHHHHHHHH		29.0128889911
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of POF14_SCHPO !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of POF14_SCHPO !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of POF14_SCHPO !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
CUL1_SCHPOcul1physical
17016471
SKP1_SCHPOskp1physical
17016471
FDFT_SCHPOerg9physical
17016471
EIF3A_SCHPOtif32physical
17016471
MUG64_SCHPOmug64physical
17016471
PMGY_SCHPOgpm1physical
17016471
SPO4_SCHPOspo4genetic
22681890
PAC2_SCHPOpac2genetic
22681890
MED19_SCHPOrox3genetic
22681890
UBC16_SCHPOubc16genetic
22681890
HMT2_SCHPOhmt2genetic
22681890
GBB_SCHPOgit5genetic
22681890
MFM2_SCHPOmfm2genetic
22681890
AATM_SCHPOSPBC725.01genetic
22681890
CYB51_SCHPOSPBC29A10.16cgenetic
22681890
SET1_SCHPOset1genetic
22681890
VMS1_SCHPOvms1genetic
22681890
MID1_SCHPOmid1genetic
22681890
YQMA_SCHPOSPCP1E11.10genetic
22681890
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of POF14_SCHPO

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Related Literatures of Post-Translational Modification

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