NTRI_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: NTRI_HUMAN
• UniProt AC: Q9P121
• Protein Name: Neurotrimin
• Gene Name: NTM
• Organism: Homo sapiens (Human).
• Sequence Length: 344
• Subcellular Localization: Cell membrane; Lipid-anchor, GPI-anchor.
• Protein Description: Neural cell adhesion molecule..
• Protein Sequence: MGVCGYLFLPWKCLVVVSLRLLFLVPTGVPVRSGDATFPKAMDNVTVRQGESATLRCTIDNRVTRVAWLNRSTILYAGNDKWCLDPRVVLLSNTQTQYSIEIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVSPKIVEISSDISINEGNNISLTCIATGRPEPTVTWRHISPKAVGFVSEDEYLEIQGITREQSGDYECSASNDVAAPVVRRVKVTVNYPPYISEAKGTGVPVGQKGTLQCEASAVPSAEFQWYKDDKRLIEGKKGVKVENRPFLSKLIFFNVSEHDYGNYTCVASNKLGHTNASIMLFGPGAVSEVSNGTSRRAGCVWLLPLLVLHLLLKF

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
44	N-linked_Glycosylation	TFPKAMDNVTVRQGE CCCCCCCCEEEECCC	20.48	UniProtKB CARBOHYD
54	Phosphorylation	VRQGESATLRCTIDN EECCCCEEEEEEECC	24.82	23403867
70	N-linked_Glycosylation	VTRVAWLNRSTILYA EEEEEEECCCEEEEE	25.75	UniProtKB CARBOHYD
125	Phosphorylation	QTDNHPKTSRVHLIV ECCCCCCCCEEEEEE	26.64	27251275
126	Phosphorylation	TDNHPKTSRVHLIVQ CCCCCCCCEEEEEEE	38.13	27251275
135	Phosphorylation	VHLIVQVSPKIVEIS EEEEEEECCCEEEEC	11.91	27251275
152	N-linked_Glycosylation	ISINEGNNISLTCIA EEECCCCCEEEEEEE	35.76	UniProtKB CARBOHYD
199	Phosphorylation	TREQSGDYECSASND CHHHCCCCEECCCCC	23.51	20736484
284	N-linked_Glycosylation	LSKLIFFNVSEHDYG CCEEEEEECCCHHCC	26.17	UniProtKB CARBOHYD
292	N-linked_Glycosylation	VSEHDYGNYTCVASN CCCHHCCCEEEEEEC	23.78	UniProtKB CARBOHYD
305	N-linked_Glycosylation	SNKLGHTNASIMLFG ECCCCCCCCEEEEEC	26.47	UniProtKB CARBOHYD
321	N-linked_Glycosylation	GAVSEVSNGTSRRAG CHHEECCCCCCCCCC	64.04	UniProtKB CARBOHYD
321	GPI-anchor	GAVSEVSNGTSRRAG CHHEECCCCCCCCCC	64.04	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of NTRI_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of NTRI_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of NTRI_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
A4_HUMAN	APP	physical	21832049
LSAMP_HUMAN	LSAMP	physical	21982860
NEGR1_HUMAN	NEGR1	physical	21982860
NTRI_HUMAN	NTM	physical	21982860
KRA32_HUMAN	KRTAP3-2	physical	25416956
CS047_HUMAN	C19orf47	physical	25416956
OPCM_HUMAN	OPCML	physical	26186194
CALR_HUMAN	CALR	physical	26186194
PDIA5_HUMAN	PDIA5	physical	26186194
FBX2_HUMAN	FBXO2	physical	26186194
OPCM_HUMAN	OPCML	physical	28514442
FBX2_HUMAN	FBXO2	physical	28514442
CALR_HUMAN	CALR	physical	28514442

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.