| UniProt ID | NF2L3_HUMAN | |
|---|---|---|
| UniProt AC | Q9Y4A8 | |
| Protein Name | Nuclear factor erythroid 2-related factor 3 | |
| Gene Name | NFE2L3 | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 694 | |
| Subcellular Localization | Nucleus . | |
| Protein Description | Activates erythroid-specific, globin gene expression.. | |
| Protein Sequence | MKHLKRWWSAGGGLLHLTLLLSLAGLRVDLDLYLLLPPPTLLQDELLFLGGPASSAYALSPFSASGGWGRAGHLHPKGRELDPAAPPEGQLLREVRALGVPFVPRTSVDAWLVHSVAAGSADEAHGLLGAAAASSTGGAGASVDGGSQAVQGGGGDPRAARSGPLDAGEEEKAPAEPTAQVPDAGGCASEENGVLREKHEAVDHSSQHEENEERVSAQKENSLQQNDDDENKIAEKPDWEAEKTTESRNERHLNGTDTSFSLEDLFQLLSSQPENSLEGISLGDIPLPGSISDGMNSSAHYHVNFSQAISQDVNLHEAILLCPNNTFRRDPTARTSQSQEPFLQLNSHTTNPEQTLPGTNLTGFLSPVDNHMRNLTSQDLLYDLDINIFDEINLMSLATEDNFDPIDVSQLFDEPDSDSGLSLDSSHNNTSVIKSNSSHSVCDEGAIGYCTDHESSSHHDLEGAVGGYYPEPSKLCHLDQSDSDFHGDLTFQHVFHNHTYHLQPTAPESTSEPFPWPGKSQKIRSRYLEDTDRNLSRDEQRAKALHIPFSVDEIVGMPVDSFNSMLSRYYLTDLQVSLIRDIRRRGKNKVAAQNCRKRKLDIILNLEDDVCNLQAKKETLKREQAQCNKAINIMKQKLHDLYHDIFSRLRDDQGRPVNPNHYALQCTHDGSILIVPKELVASGHKKETQKGKRK | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
|
|
||
* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 77 | Ubiquitination | RAGHLHPKGRELDPA CCCCCCCCCCCCCCC | 60.91 | 22817900 | |
| 219 | Ubiquitination | EERVSAQKENSLQQN HHHHHHHHHHHCCCC | 59.59 | 22817900 | |
| 347 | Phosphorylation | EPFLQLNSHTTNPEQ CCEEECCCCCCCHHH | 30.70 | - | |
| 366 | Phosphorylation | TNLTGFLSPVDNHMR CCCCCCCCCCCHHHH | 22.18 | - | |
| 616 | Ubiquitination | DVCNLQAKKETLKRE HHHHHHHHHHHHHHH | 37.88 | 32015554 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of NF2L3_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of NF2L3_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of NF2L3_HUMAN !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| MAFK_HUMAN | MAFK | physical | 10037736 | |
| BACH2_HUMAN | BACH2 | physical | 23661758 | |
| NF2L3_HUMAN | NFE2L3 | physical | 23661758 | |
| NF2L2_HUMAN | NFE2L2 | physical | 23661758 | |
| NF2L1_HUMAN | NFE2L1 | physical | 23661758 | |
| NFE2_HUMAN | NFE2 | physical | 23661758 | |
| MAFG_HUMAN | MAFG | physical | 23661758 | |
| MAFF_HUMAN | MAFF | physical | 23661758 | |
| CREB3_HUMAN | CREB3 | physical | 23661758 | |
| FBXW7_HUMAN | FBXW7 | physical | 26306035 | |
| GSK3B_HUMAN | GSK3B | physical | 26306035 | |
| MAFK_HUMAN | MAFK | physical | 28514442 | |
| MAFG_HUMAN | MAFG | physical | 28514442 | |
| HCFC2_HUMAN | HCFC2 | physical | 28514442 | |
| HCFC1_HUMAN | HCFC1 | physical | 28514442 |
| Kegg Disease | ||||||
|---|---|---|---|---|---|---|
| There are no disease associations of PTM sites. | ||||||
| OMIM Disease | ||||||
| There are no disease associations of PTM sites. | ||||||
| Kegg Drug | ||||||
| There are no disease associations of PTM sites. | ||||||
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
loading...
