| UniProt ID | MTAP2_HUMAN | |
|---|---|---|
| UniProt AC | P11137 | |
| Protein Name | Microtubule-associated protein 2 | |
| Gene Name | MAP2 | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 1827 | |
| Subcellular Localization | Cytoplasm, cytoskeleton . Cell projection, dendrite . | |
| Protein Description | The exact function of MAP2 is unknown but MAPs may stabilize the microtubules against depolymerization. They also seem to have a stiffening effect on microtubules.. | |
| Protein Sequence | MADERKDEAKAPHWTSAPLTEASAHSHPPEIKDQGGAGEGLVRSANGFPYREDEEGAFGEHGSQGTYSNTKENGINGELTSADRETAEEVSARIVQVVTAEAVAVLKGEQEKEAQHKDQTAALPLAAEETANLPPSPPPSPASEQTVTVEEDLLTASKMEFHDQQELTPSTAEPSDQKEKESEKQSKPGEDLKHAALVSQPETTKTYPDKKDMQGTEEEKAPLALFGHTLVASLEDMKQKTEPSLVVPGIDLPKEPPTPKEQKDWFIEMPTEAKKDEWGLVAPISPGPLTPMREKDVFDDIPKWEGKQFDSPMPSPFQGGSFTLPLDVMKNEIVTETSPFAPAFLQPDDKKSLQQTSGPATAKDSFKIEEPHEAKPDKMAEAPPSEAMTLPKDAHIPVVEEHVMGKVLEEEKEAINQETVQQRDTFTPSGQEPILTEKETELKLEEKTTISDKEAVPKESKPPKPADEEIGIIQTSTEHTFSEQKDQEPTTDMLKQDSFPVSLEQAVTDSAMTSKTLEKAMTEPSALIEKSSIQELFEMRVDDKDKIEGVGAATSAELDMPFYEDKSGMSKYFETSALKEEATKSIEPGSDYYELSDTRESVHESIDTMSPMHKNGDKEFQTGKESQPSPPAQEAGYSTLAQSYPSDLPEEPSSPQERMFTIDPKVYGEKRDLHSKNKDDLTLSRSLGLGGRSAIEQRSMSINLPMSCLDSIALGFNFGRGHDLSPLASDILTNTSGSMDEGDDYLPATTPALEKAPCFPVESKEEEQIEKVKATGEESTQAEISCESPFLAKDFYKNGTVMAPDLPEMLDLAGTRSRLASVSADAEVARRKSVPSETVVEDSRTGLPPVTDENHVIVKTDSQLEDLGYCVFNKYTVPLPSPVQDSENLSGESGTFYEGTDDKVRRDLATDLSLIEVKLAAAGRVKDEFSVDKEASAHISGDKSGLSKEFDQEKKANDRLDTVLEKSEEHADSKEHAKKTEEAGDEIETFGLGVTYEQALAKDLSIPTDASSEKAEKGLSSVPEIAEVEPSKKVEQGLDFAVQGQLDVKISDFGQMASGLNIDDRRATELKLEATQDMTPSSKAPQEADAFMGVESGHMKEGTKVSETEVKEKVAKPDLVHQEAVDKEESYESSGEHESLTMESLKADEGKKETSPESSLIQDEIAVKLSVEIPCPPAVSEADLATDERADVQMEFIQGPKEESKETPDISITPSDVAEPLHETIVSEPAEIQSEEEEIEAQGEYDKLLFRSDTLQITDLGVSGAREEFVETCPSEHKGVIESVVTIEDDFITVVQTTTDEGESGSHSVRFAALEQPEVERRPSPHDEEEFEVEEAAEAQAEPKDGSPEAPASPEREEVALSEYKTETYDDYKDETTIDDSIMDADSLWVDTQDDDRSIMTEQLETIPKEEKAEKEARRSSLEKHRKEKPFKTGRGRISTPERKVAKKEPSTVSRDEVRRKKAVYKKAELAKKTEVQAHSPSRKFILKPAIKYTRPTHLSCVKRKTTAAGGESALAPSVFKQAKDKVSDGVTKSPEKRSSLPRPSSILPPRRGVSGDRDENSFSLNSSISSSARRTTRSEPIRRAGKSGTSTPTTPGSTAITPGTPPSYSSRTPGTPGTPSYPRTPHTPGTPKSAILVPSEKKVAIIRTPPKSPATPKQLRLINQPLPDLKNVKSKIGSTDNIKYQPKGGQVQIVTKKIDLSHVTSKCGSLKNIRHRPGGGRVKIESVKLDFKEKAQAKVGSLDNAHHVPGGGNVKIDSQKLNFREHAKARVDHGAEIITQSPGRSSVASPRRLSNVSSSGSINLLESPQLATLAEDVTAALAKQGL | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 20 | Phosphorylation | HWTSAPLTEASAHSH CCCCCCCCHHHHCCC | 27251275 | ||
| 23 | Phosphorylation | SAPLTEASAHSHPPE CCCCCHHHHCCCCCC | 27251275 | ||
| 26 | Phosphorylation | LTEASAHSHPPEIKD CCHHHHCCCCCCCCC | 27251275 | ||
| 50 | Phosphorylation | RSANGFPYREDEEGA CCCCCCCCCCCCCCC | - | ||
| 63 | Phosphorylation | GAFGEHGSQGTYSNT CCCCCCCCCCCCCCC | 17525332 | ||
| 66 | Phosphorylation | GEHGSQGTYSNTKEN CCCCCCCCCCCCCCC | 27732954 | ||
| 67 | Phosphorylation | EHGSQGTYSNTKENG CCCCCCCCCCCCCCC | 15536091 | ||
| 67 (in isoform 2) | Phosphorylation | - | 15536091 | ||
| 120 | Phosphorylation | EAQHKDQTAALPLAA HHHCCCCCCHHCHHH | 29514088 | ||
| 120 (in isoform 3) | Phosphorylation | - | 30177828 | ||
| 130 | Phosphorylation | LPLAAEETANLPPSP HCHHHHHHCCCCCCC | 29514088 | ||
| 130 (in isoform 3) | Phosphorylation | - | 26503514 | ||
| 136 | Phosphorylation | ETANLPPSPPPSPAS HHCCCCCCCCCCCCC | 29514088 | ||
| 136 (in isoform 2) | Phosphorylation | - | 25921289 | ||
| 136 (in isoform 3) | Phosphorylation | - | 24076635 | ||
| 136 (in isoform 4) | Phosphorylation | - | 25921289 | ||
| 140 | Phosphorylation | LPPSPPPSPASEQTV CCCCCCCCCCCCCEE | 29514088 | ||
| 140 (in isoform 2) | Phosphorylation | - | 25921289 | ||
| 140 (in isoform 3) | Phosphorylation | - | 24076635 | ||
| 140 (in isoform 4) | Phosphorylation | - | 25921289 | ||
| 143 | Phosphorylation | SPPPSPASEQTVTVE CCCCCCCCCCEEEEE | 29514088 | ||
| 143 (in isoform 2) | Phosphorylation | - | 28348404 | ||
| 143 (in isoform 3) | Phosphorylation | - | 26503514 | ||
| 143 (in isoform 4) | Phosphorylation | - | 28348404 | ||
| 146 | Phosphorylation | PSPASEQTVTVEEDL CCCCCCCEEEEEHHH | 29514088 | ||
| 146 (in isoform 2) | Phosphorylation | - | 28348404 | ||
| 146 (in isoform 3) | Phosphorylation | - | 30177828 | ||
| 146 (in isoform 4) | Phosphorylation | - | 28348404 | ||
| 148 | Phosphorylation | PASEQTVTVEEDLLT CCCCCEEEEEHHHHH | 29514088 | ||
| 148 (in isoform 2) | Phosphorylation | - | 28348404 | ||
| 148 (in isoform 3) | Phosphorylation | - | 26503514 | ||
| 148 (in isoform 4) | Phosphorylation | - | 28348404 | ||
| 153 (in isoform 3) | Phosphorylation | - | 26503514 | ||
| 155 | Phosphorylation | TVEEDLLTASKMEFH EEEHHHHHHHHCEEC | 29514088 | ||
| 157 | Phosphorylation | EEDLLTASKMEFHDQ EHHHHHHHHCEECCC | 30177828 | ||
| 168 | Phosphorylation | FHDQQELTPSTAEPS ECCCCCCCCCCCCCC | 28674419 | ||
| 170 | Phosphorylation | DQQELTPSTAEPSDQ CCCCCCCCCCCCCHH | 27732954 | ||
| 185 (in isoform 4) | Phosphorylation | - | 29507054 | ||
| 186 (in isoform 4) | Phosphorylation | - | 27050516 | ||
| 188 (in isoform 4) | Phosphorylation | - | 23911959 | ||
| 197 (in isoform 4) | Phosphorylation | - | 28674419 | ||
| 199 | O-linked_Glycosylation | LKHAALVSQPETTKT HHHHHHCCCCCCCCC | 28657654 | ||
| 203 (in isoform 4) | Phosphorylation | - | - | ||
| 205 (in isoform 4) | Phosphorylation | - | 19276368 | ||
| 213 (in isoform 4) | Phosphorylation | - | 28348404 | ||
| 214 (in isoform 4) | Phosphorylation | - | 19276368 | ||
| 216 | Phosphorylation | DKKDMQGTEEEKAPL CCCCCCCCCCCCCCH | 22673903 | ||
| 217 (in isoform 4) | Phosphorylation | - | 28348404 | ||
| 218 (in isoform 4) | Phosphorylation | - | 28348404 | ||
| 233 | Phosphorylation | FGHTLVASLEDMKQK HCHHHHHCHHHHHHH | 29514088 | ||
| 241 | O-linked_Glycosylation | LEDMKQKTEPSLVVP HHHHHHHCCCCCCCC | 28657654 | ||
| 241 | Phosphorylation | LEDMKQKTEPSLVVP HHHHHHHCCCCCCCC | 27251275 | ||
| 258 | Phosphorylation | DLPKEPPTPKEQKDW CCCCCCCCCHHHCCC | 28674419 | ||
| 285 | Phosphorylation | WGLVAPISPGPLTPM CCCCCCCCCCCCCCC | 30266825 | ||
| 290 | Phosphorylation | PISPGPLTPMREKDV CCCCCCCCCCCHHCC | 27273156 | ||
| 311 | Phosphorylation | WEGKQFDSPMPSPFQ CCCCCCCCCCCCCCC | 22199227 | ||
| 315 | Phosphorylation | QFDSPMPSPFQGGSF CCCCCCCCCCCCCCE | 25850435 | ||
| 321 | Phosphorylation | PSPFQGGSFTLPLDV CCCCCCCCEEEEEHH | 24117733 | ||
| 323 | Phosphorylation | PFQGGSFTLPLDVMK CCCCCCEEEEEHHHC | 24117733 | ||
| 323 (in isoform 2) | Phosphorylation | - | - | ||
| 335 | O-linked_Glycosylation | VMKNEIVTETSPFAP HHCCCEECCCCCCCC | 28657654 | ||
| 335 | Phosphorylation | VMKNEIVTETSPFAP HHCCCEECCCCCCCC | 27732954 | ||
| 337 | Phosphorylation | KNEIVTETSPFAPAF CCCEECCCCCCCCHH | 27732954 | ||
| 338 | Phosphorylation | NEIVTETSPFAPAFL CCEECCCCCCCCHHC | 22199227 | ||
| 354 | Phosphorylation | PDDKKSLQQTSGPAT CCCHHHHHHCCCCCC | 24719451 | ||
| 354 (in isoform 2) | Phosphorylation | - | - | ||
| 357 | Phosphorylation | KKSLQQTSGPATAKD HHHHHHCCCCCCHHH | - | ||
| 361 | Phosphorylation | QQTSGPATAKDSFKI HHCCCCCCHHHCCCC | - | ||
| 385 | Phosphorylation | KMAEAPPSEAMTLPK HHCCCCCHHCCCCCC | 8631898 | ||
| 386 (in isoform 2) | Phosphorylation | - | - | ||
| 411 (in isoform 4) | Phosphorylation | - | - | ||
| 412 | Methylation | GKVLEEEKEAINQET HHHHHHHHHHHCHHH | - | ||
| 418 (in isoform 4) | Phosphorylation | - | - | ||
| 419 | Phosphorylation | KEAINQETVQQRDTF HHHHCHHHHHCHHCC | 30257219 | ||
| 425 | Phosphorylation | ETVQQRDTFTPSGQE HHHHCHHCCCCCCCC | 24117733 | ||
| 427 | Phosphorylation | VQQRDTFTPSGQEPI HHCHHCCCCCCCCCC | 29255136 | ||
| 428 (in isoform 4) | Phosphorylation | - | - | ||
| 429 | Phosphorylation | QRDTFTPSGQEPILT CHHCCCCCCCCCCCC | 24117733 | ||
| 436 | Phosphorylation | SGQEPILTEKETELK CCCCCCCCCCHHEEE | 24117733 | ||
| 451 | Phosphorylation | LEEKTTISDKEAVPK EEECCCCCCCCCCCC | 25332170 | ||
| 498 | Phosphorylation | TDMLKQDSFPVSLEQ CHHHHCCCCCCCHHH | - | ||
| 502 | O-linked_Glycosylation | KQDSFPVSLEQAVTD HCCCCCCCHHHHHCH | 28657654 | ||
| 502 | Phosphorylation | KQDSFPVSLEQAVTD HCCCCCCCHHHHHCH | 22210691 | ||
| 508 | Phosphorylation | VSLEQAVTDSAMTSK CCHHHHHCHHHHCHH | 22210691 | ||
| 514 | Phosphorylation | VTDSAMTSKTLEKAM HCHHHHCHHHHHHHH | 20166139 | ||
| 516 | Phosphorylation | DSAMTSKTLEKAMTE HHHHCHHHHHHHHHC | - | ||
| 522 | O-linked_Glycosylation | KTLEKAMTEPSALIE HHHHHHHHCHHHHHC | 28657654 | ||
| 522 | Phosphorylation | KTLEKAMTEPSALIE HHHHHHHHCHHHHHC | 27499020 | ||
| 531 | Phosphorylation | PSALIEKSSIQELFE HHHHHCHHHHHHHHH | 27732954 | ||
| 532 | Phosphorylation | SALIEKSSIQELFEM HHHHCHHHHHHHHHC | 27732954 | ||
| 563 | Phosphorylation | AELDMPFYEDKSGMS EECCCCCCCCCCHHH | 28851738 | ||
| 572 | Phosphorylation | DKSGMSKYFETSALK CCCHHHHHHHHHHHH | 28674419 | ||
| 583 | Phosphorylation | SALKEEATKSIEPGS HHHHHHHHHCCCCCC | 25954137 | ||
| 585 | Phosphorylation | LKEEATKSIEPGSDY HHHHHHHCCCCCCCC | 25954137 | ||
| 590 | Phosphorylation | TKSIEPGSDYYELSD HHCCCCCCCCEECCC | 27642862 | ||
| 592 | Phosphorylation | SIEPGSDYYELSDTR CCCCCCCCEECCCCH | 24927040 | ||
| 593 | Phosphorylation | IEPGSDYYELSDTRE CCCCCCCEECCCCHH | 25884760 | ||
| 596 | Phosphorylation | GSDYYELSDTRESVH CCCCEECCCCHHHHH | 27732954 | ||
| 598 | Phosphorylation | DYYELSDTRESVHES CCEECCCCHHHHHHH | 25954137 | ||
| 601 | Phosphorylation | ELSDTRESVHESIDT ECCCCHHHHHHHHHH | 29255136 | ||
| 605 | Phosphorylation | TRESVHESIDTMSPM CHHHHHHHHHHCCCC | 27251275 | ||
| 608 | Phosphorylation | SVHESIDTMSPMHKN HHHHHHHHCCCCCCC | 29255136 | ||
| 610 | Phosphorylation | HESIDTMSPMHKNGD HHHHHHCCCCCCCCC | 29255136 | ||
| 626 | Phosphorylation | EFQTGKESQPSPPAQ CCCCCCCCCCCCCHH | 22199227 | ||
| 629 | Phosphorylation | TGKESQPSPPAQEAG CCCCCCCCCCHHHCC | 22199227 | ||
| 637 | Phosphorylation | PPAQEAGYSTLAQSY CCHHHCCCCHHHHHC | 22199227 | ||
| 638 | Phosphorylation | PAQEAGYSTLAQSYP CHHHCCCCHHHHHCC | 25850435 | ||
| 639 | Phosphorylation | AQEAGYSTLAQSYPS HHHCCCCHHHHHCCC | 25850435 | ||
| 643 | Phosphorylation | GYSTLAQSYPSDLPE CCCHHHHHCCCCCCC | 23090842 | ||
| 644 | Phosphorylation | YSTLAQSYPSDLPEE CCHHHHHCCCCCCCC | 23090842 | ||
| 646 | Phosphorylation | TLAQSYPSDLPEEPS HHHHHCCCCCCCCCC | 23090842 | ||
| 653 | Phosphorylation | SDLPEEPSSPQERMF CCCCCCCCCCCCCCE | 26657352 | ||
| 654 | Phosphorylation | DLPEEPSSPQERMFT CCCCCCCCCCCCCEE | 21955146 | ||
| 682 | Phosphorylation | SKNKDDLTLSRSLGL CCCHHHCHHHHHCCC | 24719451 | ||
| 686 | Phosphorylation | DDLTLSRSLGLGGRS HHCHHHHHCCCCCHH | 28674419 | ||
| 699 | Phosphorylation | RSAIEQRSMSINLPM HHHHHHHHHCCCCCH | 24719451 | ||
| 701 | Phosphorylation | AIEQRSMSINLPMSC HHHHHHHCCCCCHHH | 28348404 | ||
| 725 | Phosphorylation | FGRGHDLSPLASDIL CCCCCCCHHHHHHHH | 25849741 | ||
| 729 | Phosphorylation | HDLSPLASDILTNTS CCCHHHHHHHHHCCC | 15345747 | ||
| 733 | Phosphorylation | PLASDILTNTSGSMD HHHHHHHHCCCCCCC | 26657352 | ||
| 735 | Phosphorylation | ASDILTNTSGSMDEG HHHHHHCCCCCCCCC | 27732954 | ||
| 736 | Phosphorylation | SDILTNTSGSMDEGD HHHHHCCCCCCCCCC | 30175587 | ||
| 738 | Phosphorylation | ILTNTSGSMDEGDDY HHHCCCCCCCCCCCC | 29507054 | ||
| 745 | Phosphorylation | SMDEGDDYLPATTPA CCCCCCCCCCCCCHH | 22617229 | ||
| 749 | Phosphorylation | GDDYLPATTPALEKA CCCCCCCCCHHHHCC | 27732954 | ||
| 750 | Phosphorylation | DDYLPATTPALEKAP CCCCCCCCHHHHCCC | 27732954 | ||
| 785 | Phosphorylation | ESTQAEISCESPFLA CCCCCEEECCCCCCC | 24117733 | ||
| 788 | Phosphorylation | QAEISCESPFLAKDF CCEEECCCCCCCCHH | 25850435 | ||
| 821 | Phosphorylation | GTRSRLASVSADAEV CCHHHHHHHCCCHHH | 29255136 | ||
| 823 | Phosphorylation | RSRLASVSADAEVAR HHHHHHHCCCHHHHH | 25884760 | ||
| 833 | Phosphorylation | AEVARRKSVPSETVV HHHHHHCCCCCCCEE | 29255136 | ||
| 836 | Phosphorylation | ARRKSVPSETVVEDS HHHCCCCCCCEECCC | 23403867 | ||
| 838 | Phosphorylation | RKSVPSETVVEDSRT HCCCCCCCEECCCCC | 23403867 | ||
| 843 | Phosphorylation | SETVVEDSRTGLPPV CCCEECCCCCCCCCC | 23403867 | ||
| 845 | Phosphorylation | TVVEDSRTGLPPVTD CEECCCCCCCCCCCC | 29514088 | ||
| 851 | O-linked_Glycosylation | RTGLPPVTDENHVIV CCCCCCCCCCCCEEE | 28657654 | ||
| 851 | Phosphorylation | RTGLPPVTDENHVIV CCCCCCCCCCCCEEE | 21406692 | ||
| 860 | Phosphorylation | ENHVIVKTDSQLEDL CCCEEEECCHHHHHC | 27732954 | ||
| 862 | Phosphorylation | HVIVKTDSQLEDLGY CEEEECCHHHHHCCE | 27732954 | ||
| 875 | Phosphorylation | GYCVFNKYTVPLPSP CEEEECCEEECCCCC | 27732954 | ||
| 876 | Phosphorylation | YCVFNKYTVPLPSPV EEEECCEEECCCCCC | 27732954 | ||
| 881 | Phosphorylation | KYTVPLPSPVQDSEN CEEECCCCCCCCCCC | 28857561 | ||
| 886 | Phosphorylation | LPSPVQDSENLSGES CCCCCCCCCCCCCCC | 27732954 | ||
| 890 | Phosphorylation | VQDSENLSGESGTFY CCCCCCCCCCCCCCC | 27732954 | ||
| 893 | Phosphorylation | SENLSGESGTFYEGT CCCCCCCCCCCCCCC | 27732954 | ||
| 895 | Phosphorylation | NLSGESGTFYEGTDD CCCCCCCCCCCCCCH | 27732954 | ||
| 913 | Phosphorylation | RDLATDLSLIEVKLA HHHHHCHHHHHHHHH | 27732954 | ||
| 930 | Phosphorylation | GRVKDEFSVDKEASA CCCCCCCCCCHHHHH | 29514088 | ||
| 936 | Phosphorylation | FSVDKEASAHISGDK CCCCHHHHHHHCCCC | - | ||
| 996 | Phosphorylation | TFGLGVTYEQALAKD HCCCCCCHHHHHHHH | 25884760 | ||
| 1005 | Phosphorylation | QALAKDLSIPTDASS HHHHHHCCCCCCCCH | 22199227 | ||
| 1008 | Phosphorylation | AKDLSIPTDASSEKA HHHCCCCCCCCHHHH | 27732954 | ||
| 1011 | Phosphorylation | LSIPTDASSEKAEKG CCCCCCCCHHHHHHC | 27732954 | ||
| 1012 | Phosphorylation | SIPTDASSEKAEKGL CCCCCCCHHHHHHCC | 27732954 | ||
| 1020 | Phosphorylation | EKAEKGLSSVPEIAE HHHHHCCCCCCHHHC | 25850435 | ||
| 1021 | Phosphorylation | KAEKGLSSVPEIAEV HHHHCCCCCCHHHCC | 27251275 | ||
| 1031 | Phosphorylation | EIAEVEPSKKVEQGL HHHCCCCCCCHHHCC | - | ||
| 1079 | Phosphorylation | LEATQDMTPSSKAPQ HHCCCCCCCCCCCCH | 28674419 | ||
| 1082 | O-linked_Glycosylation | TQDMTPSSKAPQEAD CCCCCCCCCCCHHHC | 28657654 | ||
| 1106 | Phosphorylation | MKEGTKVSETEVKEK CCCCCCCCHHHHHHH | - | ||
| 1108 | Phosphorylation | EGTKVSETEVKEKVA CCCCCCHHHHHHHHC | - | ||
| 1130 | Phosphorylation | EAVDKEESYESSGEH HHCCHHHHHCCCCCC | 29514088 | ||
| 1131 | Phosphorylation | AVDKEESYESSGEHE HCCHHHHHCCCCCCC | 25307156 | ||
| 1133 | Phosphorylation | DKEESYESSGEHESL CHHHHHCCCCCCCCC | 25307156 | ||
| 1134 | Phosphorylation | KEESYESSGEHESLT HHHHHCCCCCCCCCC | 29514088 | ||
| 1139 | Phosphorylation | ESSGEHESLTMESLK CCCCCCCCCCHHHHC | 29514088 | ||
| 1141 | Phosphorylation | SGEHESLTMESLKAD CCCCCCCCHHHHCCC | 29514088 | ||
| 1144 | Phosphorylation | HESLTMESLKADEGK CCCCCHHHHCCCCCC | 30177828 | ||
| 1154 | Phosphorylation | ADEGKKETSPESSLI CCCCCCCCCCCHHHC | 30266825 | ||
| 1155 | Phosphorylation | DEGKKETSPESSLIQ CCCCCCCCCCHHHCC | 30266825 | ||
| 1158 | Phosphorylation | KKETSPESSLIQDEI CCCCCCCHHHCCCEE | 30266825 | ||
| 1159 | Phosphorylation | KETSPESSLIQDEIA CCCCCCHHHCCCEEE | 30266825 | ||
| 1180 | Phosphorylation | IPCPPAVSEADLATD ECCCCCCCHHHHCCC | 27732954 | ||
| 1227 | Phosphorylation | PLHETIVSEPAEIQS CHHHHHCCCCCCCCC | 25921289 | ||
| 1234 | Phosphorylation | SEPAEIQSEEEEIEA CCCCCCCCHHHHHHH | 18510355 | ||
| 1252 | Phosphorylation | YDKLLFRSDTLQITD HHHHHEECCCEEEEE | 24117733 | ||
| 1254 | Phosphorylation | KLLFRSDTLQITDLG HHHEECCCEEEEECC | 24117733 | ||
| 1258 | Phosphorylation | RSDTLQITDLGVSGA ECCCEEEEECCCCCC | 24117733 | ||
| 1263 | Phosphorylation | QITDLGVSGAREEFV EEEECCCCCCHHHHH | 24117733 | ||
| 1324 | Phosphorylation | PEVERRPSPHDEEEF CCCCCCCCCCCHHHC | 29255136 | ||
| 1347 | Phosphorylation | QAEPKDGSPEAPASP HCCCCCCCCCCCCCH | 30266825 | ||
| 1353 | Phosphorylation | GSPEAPASPEREEVA CCCCCCCCHHHHHHH | 30266825 | ||
| 1362 | Phosphorylation | EREEVALSEYKTETY HHHHHHHHHCCCCCC | 30266825 | ||
| 1364 | Phosphorylation | EEVALSEYKTETYDD HHHHHHHCCCCCCCC | 30576142 | ||
| 1366 | Phosphorylation | VALSEYKTETYDDYK HHHHHCCCCCCCCCC | - | ||
| 1368 | Phosphorylation | LSEYKTETYDDYKDE HHHCCCCCCCCCCCC | - | ||
| 1369 | Phosphorylation | SEYKTETYDDYKDET HHCCCCCCCCCCCCC | - | ||
| 1381 | Phosphorylation | DETTIDDSIMDADSL CCCCCCCCCCCCCCC | 30576142 | ||
| 1398 | Phosphorylation | DTQDDDRSIMTEQLE ECCCCCCCHHHHHHH | 29255136 | ||
| 1401 | Phosphorylation | DDDRSIMTEQLETIP CCCCCHHHHHHHHCC | 29255136 | ||
| 1406 | Phosphorylation | IMTEQLETIPKEEKA HHHHHHHHCCHHHHH | 29083192 | ||
| 1420 | Phosphorylation | AEKEARRSSLEKHRK HHHHHHHHHHHHHHC | 29514088 | ||
| 1421 | Phosphorylation | EKEARRSSLEKHRKE HHHHHHHHHHHHHCC | 29514088 | ||
| 1427 | Acetylation | SSLEKHRKEKPFKTG HHHHHHHCCCCCCCC | 7711235 | ||
| 1439 | Phosphorylation | KTGRGRISTPERKVA CCCCCCCCCHHHHHC | 30576142 | ||
| 1440 | Phosphorylation | TGRGRISTPERKVAK CCCCCCCCHHHHHCC | 25332170 | ||
| 1447 | Ubiquitination | TPERKVAKKEPSTVS CHHHHHCCCCCCCCC | - | ||
| 1448 | Ubiquitination | PERKVAKKEPSTVSR HHHHHCCCCCCCCCH | - | ||
| 1480 | Phosphorylation | KTEVQAHSPSRKFIL HCCCCCCCCCCCEEE | 28985074 | ||
| 1482 | Phosphorylation | EVQAHSPSRKFILKP CCCCCCCCCCEEECC | 27732954 | ||
| 1493 | Phosphorylation | ILKPAIKYTRPTHLS EECCEEHHCCCCCHH | 22461510 | ||
| 1494 | Phosphorylation | LKPAIKYTRPTHLSC ECCEEHHCCCCCHHH | 22461510 | ||
| 1497 | Phosphorylation | AIKYTRPTHLSCVKR EEHHCCCCCHHHEEC | 22461510 | ||
| 1500 | Phosphorylation | YTRPTHLSCVKRKTT HCCCCCHHHEECCCC | - | ||
| 1505 | Acetylation | HLSCVKRKTTAAGGE CHHHEECCCCCCCCH | 11688139 | ||
| 1506 | Phosphorylation | LSCVKRKTTAAGGES HHHEECCCCCCCCHH | 21712546 | ||
| 1524 | Acetylation | PSVFKQAKDKVSDGV HHHHHHHHHHCCCCC | 11688147 | ||
| 1528 | Phosphorylation | KQAKDKVSDGVTKSP HHHHHHCCCCCCCCH | 23403867 | ||
| 1532 | Phosphorylation | DKVSDGVTKSPEKRS HHCCCCCCCCHHHHC | 29255136 | ||
| 1534 | Phosphorylation | VSDGVTKSPEKRSSL CCCCCCCCHHHHCCC | 29255136 | ||
| 1539 | Phosphorylation | TKSPEKRSSLPRPSS CCCHHHHCCCCCCHH | 23927012 | ||
| 1540 | Phosphorylation | KSPEKRSSLPRPSSI CCHHHHCCCCCCHHC | 23927012 | ||
| 1545 | Phosphorylation | RSSLPRPSSILPPRR HCCCCCCHHCCCCCC | 27273156 | ||
| 1546 | Phosphorylation | SSLPRPSSILPPRRG CCCCCCHHCCCCCCC | 27273156 | ||
| 1555 | Phosphorylation | LPPRRGVSGDRDENS CCCCCCCCCCCCCCC | 29255136 | ||
| 1562 | Phosphorylation | SGDRDENSFSLNSSI CCCCCCCCEECCHHC | 29255136 | ||
| 1564 | Phosphorylation | DRDENSFSLNSSISS CCCCCCEECCHHCCC | 29255136 | ||
| 1567 | Phosphorylation | ENSFSLNSSISSSAR CCCEECCHHCCCCCC | 28857561 | ||
| 1568 | Phosphorylation | NSFSLNSSISSSARR CCEECCHHCCCCCCC | 28857561 | ||
| 1571 | Phosphorylation | SLNSSISSSARRTTR ECCHHCCCCCCCCCC | 22912867 | ||
| 1572 | Phosphorylation | LNSSISSSARRTTRS CCHHCCCCCCCCCCC | 28674419 | ||
| 1588 | Phosphorylation | PIRRAGKSGTSTPTT CCHHCCCCCCCCCCC | 25072903 | ||
| 1590 | Phosphorylation | RRAGKSGTSTPTTPG HHCCCCCCCCCCCCC | 25072903 | ||
| 1591 | Phosphorylation | RAGKSGTSTPTTPGS HCCCCCCCCCCCCCC | 22617229 | ||
| 1592 | Phosphorylation | AGKSGTSTPTTPGST CCCCCCCCCCCCCCC | 25072903 | ||
| 1594 | Phosphorylation | KSGTSTPTTPGSTAI CCCCCCCCCCCCCCC | 21082442 | ||
| 1595 | Phosphorylation | SGTSTPTTPGSTAIT CCCCCCCCCCCCCCC | 21082442 | ||
| 1598 | Phosphorylation | STPTTPGSTAITPGT CCCCCCCCCCCCCCC | 22617229 | ||
| 1599 | Phosphorylation | TPTTPGSTAITPGTP CCCCCCCCCCCCCCC | 25072903 | ||
| 1602 | Phosphorylation | TPGSTAITPGTPPSY CCCCCCCCCCCCCCC | 22617229 | ||
| 1605 | Phosphorylation | STAITPGTPPSYSSR CCCCCCCCCCCCCCC | 28355574 | ||
| 1608 | Phosphorylation | ITPGTPPSYSSRTPG CCCCCCCCCCCCCCC | 30278072 | ||
| 1609 | Phosphorylation | TPGTPPSYSSRTPGT CCCCCCCCCCCCCCC | 25072903 | ||
| 1610 | Phosphorylation | PGTPPSYSSRTPGTP CCCCCCCCCCCCCCC | 25072903 | ||
| 1611 | Phosphorylation | GTPPSYSSRTPGTPG CCCCCCCCCCCCCCC | 30278072 | ||
| 1613 | Phosphorylation | PPSYSSRTPGTPGTP CCCCCCCCCCCCCCC | 29255136 | ||
| 1616 | Phosphorylation | YSSRTPGTPGTPSYP CCCCCCCCCCCCCCC | 29255136 | ||
| 1619 | Phosphorylation | RTPGTPGTPSYPRTP CCCCCCCCCCCCCCC | 29255136 | ||
| 1621 | Phosphorylation | PGTPGTPSYPRTPHT CCCCCCCCCCCCCCC | 25850435 | ||
| 1622 | Phosphorylation | GTPGTPSYPRTPHTP CCCCCCCCCCCCCCC | 25884760 | ||
| 1625 | Phosphorylation | GTPSYPRTPHTPGTP CCCCCCCCCCCCCCC | 23403867 | ||
| 1628 | Phosphorylation | SYPRTPHTPGTPKSA CCCCCCCCCCCCCCE | 29743597 | ||
| 1631 | Phosphorylation | RTPHTPGTPKSAILV CCCCCCCCCCCEEEE | 22617229 | ||
| 1634 | Phosphorylation | HTPGTPKSAILVPSE CCCCCCCCEEEECCC | 26657352 | ||
| 1640 | Phosphorylation | KSAILVPSEKKVAII CCEEEECCCCEEEEE | 29255136 | ||
| 1649 | Phosphorylation | KKVAIIRTPPKSPAT CEEEEEECCCCCCCC | 29255136 | ||
| 1653 | Phosphorylation | IIRTPPKSPATPKQL EEECCCCCCCCHHHH | 30278072 | ||
| 1656 | Phosphorylation | TPPKSPATPKQLRLI CCCCCCCCHHHHHHH | 23927012 | ||
| 1675 | Phosphorylation | PDLKNVKSKIGSTDN CCHHCHHHHCCCCCC | 11029056 | ||
| 1679 | Phosphorylation | NVKSKIGSTDNIKYQ CHHHHCCCCCCEEEC | 25850435 | ||
| 1680 | Phosphorylation | VKSKIGSTDNIKYQP HHHHCCCCCCEEECC | 25850435 | ||
| 1702 | Phosphorylation | VTKKIDLSHVTSKCG EEEEEEHHHHHHCCC | 21828286 | ||
| 1705 | Phosphorylation | KIDLSHVTSKCGSLK EEEHHHHHHCCCCCC | 29083192 | ||
| 1706 | Phosphorylation | IDLSHVTSKCGSLKN EEHHHHHHCCCCCCC | 24173317 | ||
| 1710 | Phosphorylation | HVTSKCGSLKNIRHR HHHHCCCCCCCCCCC | 22817900 | ||
| 1727 | Phosphorylation | GGRVKIESVKLDFKE CCCEEEEEEECCHHH | 24117733 | ||
| 1742 | Phosphorylation | KAQAKVGSLDNAHHV HHHHHHCCCCCCCCC | 25849741 | ||
| 1759 | Phosphorylation | GGNVKIDSQKLNFRE CCCCEECCCCCCHHH | 28857561 | ||
| 1780 | Phosphorylation | DHGAEIITQSPGRSS HCCCEEEECCCCCCC | 30266825 | ||
| 1782 | Phosphorylation | GAEIITQSPGRSSVA CCEEEECCCCCCCCC | 29255136 | ||
| 1786 | Phosphorylation | ITQSPGRSSVASPRR EECCCCCCCCCCCCC | 26503892 | ||
| 1787 | Phosphorylation | TQSPGRSSVASPRRL ECCCCCCCCCCCCCC | 26503892 | ||
| 1790 | Phosphorylation | PGRSSVASPRRLSNV CCCCCCCCCCCCCCC | 26503892 | ||
| 1795 | Phosphorylation | VASPRRLSNVSSSGS CCCCCCCCCCCCCCC | 30278072 | ||
| 1798 | Phosphorylation | PRRLSNVSSSGSINL CCCCCCCCCCCCCCC | 30278072 | ||
| 1799 | Phosphorylation | RRLSNVSSSGSINLL CCCCCCCCCCCCCCC | 30278072 | ||
| 1800 | Phosphorylation | RLSNVSSSGSINLLE CCCCCCCCCCCCCCC | 30278072 | ||
| 1802 | Phosphorylation | SNVSSSGSINLLESP CCCCCCCCCCCCCCH | 30278072 | ||
| 1808 | Phosphorylation | GSINLLESPQLATLA CCCCCCCCHHHHHHH | 22199227 | ||
| 1813 | Phosphorylation | LESPQLATLAEDVTA CCCHHHHHHHHHHHH | 22199227 | ||
| 1819 | Phosphorylation | ATLAEDVTAALAKQG HHHHHHHHHHHHHCC | 21406692 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
| 50 | Y | Phosphorylation | Kinase | FYN | P06241 | PSP |
| 67 | Y | Phosphorylation | Kinase | FYN | P06241 | PSP |
| 67 | Y | Phosphorylation | Kinase | FYN | P06241 | PSP |
| 67 | Y | Phosphorylation | Kinase | FYN | P06241 | GPS |
| 67 | Y | Phosphorylation | Kinase | LYN | P07948 | PhosphoELM |
| 1679 | S | Phosphorylation | Kinase | PRKACA | P17612 | GPS |
| 1679 | S | Phosphorylation | Kinase | MARK1 | Q9P0L2 | Uniprot |
| 1710 | S | Phosphorylation | Kinase | PRKACA | P17612 | GPS |
| 1782 | S | Phosphorylation | Kinase | PRKACA | P17612 | GPS |
| Modified Location | Modified Residue | Modification | Function | Reference |
|---|---|---|---|---|
| 323 | S | Phosphorylation |
| - |
| 354 | S | Phosphorylation |
| - |
| 386 | S | Phosphorylation |
| - |
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of MTAP2_HUMAN !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| FYN_HUMAN | FYN | physical | 11546790 | |
| NFL_HUMAN | NEFL | physical | 1902666 | |
| MTAP2_HUMAN | MAP2 | physical | 10527895 | |
| NEDD4_HUMAN | NEDD4 | physical | 19953087 | |
| TBA1A_HUMAN | TUBA1A | physical | 2777757 | |
| ACTN1_HUMAN | ACTN1 | physical | 2777757 | |
| A4_HUMAN | APP | physical | 21832049 | |
| ACTB_HUMAN | ACTB | physical | 7820861 | |
| DHX9_HUMAN | DHX9 | physical | 22863883 | |
| DC1I2_HUMAN | DYNC1I2 | physical | 22863883 | |
| ROA0_HUMAN | HNRNPA0 | physical | 22863883 | |
| IF2B3_HUMAN | IGF2BP3 | physical | 22863883 | |
| PRS8_HUMAN | PSMC5 | physical | 22863883 | |
| PSD13_HUMAN | PSMD13 | physical | 22863883 | |
| PSMD8_HUMAN | PSMD8 | physical | 22863883 | |
| RL23A_HUMAN | RPL23A | physical | 22863883 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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