MAK1_SCHPO - dbPTM
MAK1_SCHPO - PTM Information in dbPTM
Basic Information of Protein
UniProt ID MAK1_SCHPO
UniProt AC Q9P7Q7
Protein Name Peroxide stress-activated histidine kinase mak1
Gene Name mak1
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length 1639
Subcellular Localization Cytoplasm .
Protein Description Involved in the control of the SAPK-dependent transcriptional response to peroxide stress. Also has a role in G2/M regulation..
Protein Sequence MRPPDDQINNNVGSNSHLEKLKEAMDHQLQKSSKIVGSFTNSQNSSVGSVHSPILESPTSLNRQHRNSFSFNNVSSPSLEDERLINFPRVNPNRLMTSKRPNELFKTSSMSSDCYSPQKSRESLNSLCHSPAPSVSSCGNALNNDNTSASHSLTDEQPFETDSSANLFKQLQEKRNRTIGNVYEMACLLVFKTGLMNFWKNIIDFFAQQFFSTQISVVEPRDLSDIYNTPWQLRCYYDGGSHYDPYSNPISVNDNLASSSYVTVVASDGSKGIIYKDPASLKHEGDLLIDSKVVQTVLERATLLVYTRKQQHIVKNTKVHDNDYFSSIPNVDDIRSIKNSWKVFHDEKLNELKKQVEISASAAQLNGLYPQKKRAFVSHFSQNRKPYSQSDISKAQSSSFSEEPSNIYDEYEQNLLSPWSRSPVASPSIQTDPNRNPFFQNCLQESSFATESSTEKSASESVSETAVNDDCKGMNFSGNRRQEDHLNDFTSFPTETAVSIVHVPLMFPCSDQTSSRGRAPIAILSFKSNLVPYPENLIASIERLIPFIFSSYSNSQSVPLLPCPTQRHLLFNTSSTDNTKELSMSASSENSDCPHKEGECVGSFCNINAKGSSLNNIPKLPRFVPVPSEFFKKNQRSWVTLKKHRLLARLKSRISKKNSKVNENLRFSLNDGENYSNETITLKKDEIVLDKSKSYACCTSESHKYVQGHCGGQAPPFPLLKVIIDSIPVHVFTADPGSGKLTWVNRKTLLYCGLNMNEQIELQFSRIHPDDLPNFLNDWKSSLFSGSGFYHEIRLQRFDNVYRYFICRAVPLRDCTGSVLHFFGTMTDVHDQKLAERELQKQSAIAANENSYRSLAEASPQIVFAANGKNGIIYANAQWLSYSGLSLESSLGLGFLSAVYHADRKKCLLPESLEGTFNNQDESNGTKTFAAEIRFRSTDGHYRWHLVKSVCVNNSADTSTNLWLGTCTDIHDHKMLEEKLQESNIEAQRIVRSKMQYLSNMSHEIRTPLIGITGMVSFLLETQMSAEQLSYARIIQQSAKSLLTVINDILDLSKVRAGMMKLTSQRFSVRAMMEDANETLGTLAFSKGIELNYTVDIDVPDIVFGDNMRMRQVALNVIGNAIKFTNVGEVFTRCSVEKIDYSTNTVVLKWECIDTGQGFNRDDQLQMFKPFSQVESSTLPRHGGSGLGLVISKELVELHNGSMSCQSRRGVGTRFMWTATFTMDKTPLKFEPPDGCCPVCFCPYEKSKQSTEDYYCADDGNDKSATNFVKLAVNKADPGRESNRRKLESDKNVQSNKYVNPFASESEFCRCGASADPYTVLFWRLYRNKPSGIKLDKSALAVVVSHTKYSSEAIGNMLQSIIDISSFKDIVRYGNTYEAFEELLENPMQSKVTHIILNLPDIEAYVLFVKSLQLCSLYKDTKFILVTSTRQKESLSKIFSDSEDCNSESIHYVLKLVKPSKFFPLFYSDSEEKGKIGALNDMTRKAAMEQKADAETLRYNLAKSGFSVLLAEDNIINIKVISRYLERIGVKFKVTMDGLQCVEEWKREKPNFYSLILMDLQMPVMDGYQACNEIRKYELENDYPKVPIVALSANALPHVVLSCKDSGFDSYLAKPITLQHLSLIISGILNYTNQSKLHK
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
14PhosphorylationQINNNVGSNSHLEKL
HCCCCCCCHHHHHHH		30.7721712547
16PhosphorylationNNNVGSNSHLEKLKE
CCCCCCHHHHHHHHH		31.0121712547
38PhosphorylationKSSKIVGSFTNSQNS
HHHCEEEEECCCCCC		20.2929996109
42PhosphorylationIVGSFTNSQNSSVGS
EEEEECCCCCCCCCE		27.9029996109
49PhosphorylationSQNSSVGSVHSPILE
CCCCCCCEECCCCCC		17.9425720772
52PhosphorylationSSVGSVHSPILESPT
CCCCEECCCCCCCCC		16.1029996109
57PhosphorylationVHSPILESPTSLNRQ
ECCCCCCCCCCCCCC		29.9929996109
68PhosphorylationLNRQHRNSFSFNNVS
CCCCCCCCCCCCCCC		23.4028889911
70PhosphorylationRQHRNSFSFNNVSSP
CCCCCCCCCCCCCCC		27.2125720772
75PhosphorylationSFSFNNVSSPSLEDE
CCCCCCCCCCCCCCH		38.3625720772
76PhosphorylationFSFNNVSSPSLEDER
CCCCCCCCCCCCCHH		17.7725720772
78PhosphorylationFNNVSSPSLEDERLI
CCCCCCCCCCCHHHH		46.4625720772
116PhosphorylationSMSSDCYSPQKSRES
CCCCCCCCCHHHHHH		27.4729996109
130PhosphorylationSLNSLCHSPAPSVSS
HHHHHHCCCCCCHHH		23.0427738172
422PhosphorylationLLSPWSRSPVASPSI
CCCCCCCCCCCCCCC		20.4328889911
426PhosphorylationWSRSPVASPSIQTDP
CCCCCCCCCCCCCCC		21.2928889911
461PhosphorylationTEKSASESVSETAVN
CCCCCCCCCCHHHCC		28.5725720772
1003PhosphorylationQYLSNMSHEIRTPLI
HHHHCCCHHCCCCHH		24.59-
1559PhosphorylationFYSLILMDLQMPVMD
CEEEEECCCCCCCCC		30.24-
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of MAK1_SCHPO !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of MAK1_SCHPO !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of MAK1_SCHPO !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
POM1_SCHPOpom1genetic
18818364
YCRE_SCHPOtrs130genetic
22681890
LAF1_SCHPOlaf1genetic
22681890
ATP10_SCHPOatp10genetic
22681890
MAK3_SCHPOmak3genetic
22681890
ARF6_SCHPOarf6genetic
22681890
DEP1_SCHPOdep1genetic
22681890
YAOF_SCHPOSPAC11D3.15genetic
22681890
KA113_SCHPOkap113genetic
22681890
NTH_SCHPOnth1genetic
22681890
YJY3_SCHPOSPCC132.03genetic
22681890
PYRE_SCHPOura5genetic
22681890
TRM13_SCHPOtrm13genetic
22681890
PDH1_SCHPOpdh1genetic
22681890
CYB51_SCHPOSPBC29A10.16cgenetic
22681890
ATP11_SCHPOatp11genetic
22681890
RL16B_SCHPOrpl1601genetic
22681890
IQW1_SCHPOiqw1genetic
22681890
TOM70_SCHPOtom70genetic
22681890
FFT3_SCHPOfft3genetic
22681890
RS17A_SCHPOrps1701genetic
22681890
PVH1_SCHPOSPBC17A3.06genetic
22681890
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of MAK1_SCHPO

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Related Literatures of Post-Translational Modification

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