UniProt ID | LYRM4_HUMAN | |
---|---|---|
UniProt AC | Q9HD34 | |
Protein Name | LYR motif-containing protein 4 | |
Gene Name | LYRM4 | |
Organism | Homo sapiens (Human). | |
Sequence Length | 91 | |
Subcellular Localization | Mitochondrion. Nucleus. | |
Protein Description | Required for nuclear and mitochondrial iron-sulfur protein biosynthesis.. | |
Protein Sequence | MAASSRAQVLSLYRAMLRESKRFSAYNYRTYAVRRIRDAFRENKNVKDPVEIQTLVNKAKRDLGVIRRQVHIGQLYSTDKLIIENRDMPRT | |
Overview of Protein Modification Sites with Functional and Structural Information | ||
* ASA = Accessible Surface Area
Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
---|---|---|---|---|---|
26 | Phosphorylation | ESKRFSAYNYRTYAV HCCCCCCCCHHHHHH | 16.13 | - | |
28 | Phosphorylation | KRFSAYNYRTYAVRR CCCCCCCHHHHHHHH | 7.52 | - | |
31 | Phosphorylation | SAYNYRTYAVRRIRD CCCCHHHHHHHHHHH | 8.29 | - | |
47 | Malonylation | FRENKNVKDPVEIQT HHHCCCCCCCHHHHH | 66.75 | 26320211 | |
47 | Succinylation | FRENKNVKDPVEIQT HHHCCCCCCCHHHHH | 66.75 | - | |
47 | Succinylation | FRENKNVKDPVEIQT HHHCCCCCCCHHHHH | 66.75 | 27452117 | |
54 | Phosphorylation | KDPVEIQTLVNKAKR CCCHHHHHHHHHHHH | 38.03 | 18452278 | |
58 | Ubiquitination | EIQTLVNKAKRDLGV HHHHHHHHHHHHHCC | 48.05 | 2097226 | |
76 | Phosphorylation | QVHIGQLYSTDKLII EECHHHCCCCCEEEE | 11.13 | 24719451 | |
77 | Phosphorylation | VHIGQLYSTDKLIIE ECHHHCCCCCEEEEC | 38.43 | 24719451 | |
85 | Phosphorylation | TDKLIIENRDMPRT- CCEEEECCCCCCCC- | 34.54 | 24719451 | |
93 | Phosphorylation | RDMPRT--------- CCCCCC--------- | 24719451 |
Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of LYRM4_HUMAN !! |
Modified Location | Modified Residue | Modification | Function | Reference | ||
---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of LYRM4_HUMAN !! |
* Distance = the distance between SAP position and PTM sites.
Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of LYRM4_HUMAN !! |
Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
---|---|---|---|---|
NECT2_HUMAN | PVRL2 | physical | 21988832 | |
NFS1_HUMAN | NFS1 | physical | 26344197 | |
ISCU_HUMAN | ISCU | physical | 27499296 | |
LYRM4_HUMAN | LYRM4 | physical | 27499296 | |
FRDA_HUMAN | FXN | physical | 27499296 | |
NFS1_HUMAN | NFS1 | physical | 27499296 | |
IDE_HUMAN | IDE | physical | 27499296 | |
NRDC_HUMAN | NRD1 | physical | 27499296 | |
CHCH2_HUMAN | CHCHD2 | physical | 27499296 | |
MPPA_HUMAN | PMPCA | physical | 27499296 | |
MPPB_HUMAN | PMPCB | physical | 27499296 | |
HOGA1_HUMAN | HOGA1 | physical | 27499296 | |
DDAH1_HUMAN | DDAH1 | physical | 27499296 | |
ECH1_HUMAN | ECH1 | physical | 27499296 | |
ODBA_HUMAN | BCKDHA | physical | 27499296 | |
ACPM_HUMAN | NDUFAB1 | physical | 27499296 | |
C1QBP_HUMAN | C1QBP | physical | 27499296 |
Kegg Disease | ||||||
---|---|---|---|---|---|---|
OMIM Disease | ||||||
615595 | Combined oxidative phosphorylation deficiency 19 (COXPD19) | |||||
Kegg Drug | ||||||
DrugBank | ||||||
There are no disease associations of PTM sites. |
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