LYRM4_HUMAN - dbPTM
LYRM4_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID LYRM4_HUMAN
UniProt AC Q9HD34
Protein Name LYR motif-containing protein 4
Gene Name LYRM4
Organism Homo sapiens (Human).
Sequence Length 91
Subcellular Localization Mitochondrion. Nucleus.
Protein Description Required for nuclear and mitochondrial iron-sulfur protein biosynthesis..
Protein Sequence MAASSRAQVLSLYRAMLRESKRFSAYNYRTYAVRRIRDAFRENKNVKDPVEIQTLVNKAKRDLGVIRRQVHIGQLYSTDKLIIENRDMPRT
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
26PhosphorylationESKRFSAYNYRTYAV
HCCCCCCCCHHHHHH
16.13-
28PhosphorylationKRFSAYNYRTYAVRR
CCCCCCCHHHHHHHH
7.52-
31PhosphorylationSAYNYRTYAVRRIRD
CCCCHHHHHHHHHHH
8.29-
47MalonylationFRENKNVKDPVEIQT
HHHCCCCCCCHHHHH
66.7526320211
47SuccinylationFRENKNVKDPVEIQT
HHHCCCCCCCHHHHH
66.75-
47SuccinylationFRENKNVKDPVEIQT
HHHCCCCCCCHHHHH
66.7527452117
54PhosphorylationKDPVEIQTLVNKAKR
CCCHHHHHHHHHHHH
38.0318452278
58UbiquitinationEIQTLVNKAKRDLGV
HHHHHHHHHHHHHCC
48.052097226
76PhosphorylationQVHIGQLYSTDKLII
EECHHHCCCCCEEEE
11.1324719451
77PhosphorylationVHIGQLYSTDKLIIE
ECHHHCCCCCEEEEC
38.4324719451
85PhosphorylationTDKLIIENRDMPRT-
CCEEEECCCCCCCC-
34.5424719451
93PhosphorylationRDMPRT---------
CCCCCC---------
24719451

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of LYRM4_HUMAN !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of LYRM4_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of LYRM4_HUMAN !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
NECT2_HUMANPVRL2physical
21988832
NFS1_HUMANNFS1physical
26344197
ISCU_HUMANISCUphysical
27499296
LYRM4_HUMANLYRM4physical
27499296
FRDA_HUMANFXNphysical
27499296
NFS1_HUMANNFS1physical
27499296
IDE_HUMANIDEphysical
27499296
NRDC_HUMANNRD1physical
27499296
CHCH2_HUMANCHCHD2physical
27499296
MPPA_HUMANPMPCAphysical
27499296
MPPB_HUMANPMPCBphysical
27499296
HOGA1_HUMANHOGA1physical
27499296
DDAH1_HUMANDDAH1physical
27499296
ECH1_HUMANECH1physical
27499296
ODBA_HUMANBCKDHAphysical
27499296
ACPM_HUMANNDUFAB1physical
27499296
C1QBP_HUMANC1QBPphysical
27499296

Drug and Disease Associations
Kegg Disease
OMIM Disease
615595Combined oxidative phosphorylation deficiency 19 (COXPD19)
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of LYRM4_HUMAN

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Related Literatures of Post-Translational Modification

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