LIMC1_HUMAN - dbPTM
LIMC1_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID LIMC1_HUMAN
UniProt AC Q9UPQ0
Protein Name LIM and calponin homology domains-containing protein 1
Gene Name LIMCH1
Organism Homo sapiens (Human).
Sequence Length 1083
Subcellular Localization
Protein Description
Protein Sequence MACPALGLEALQPLQPEPPPEPAFSEAQKWIEQVTGRSFGDKDFRTGLENGILLCELLNAIKPGLVKKINRLPTPIAGLDNIILFLRGCKELGLKESQLFDPSDLQDTSNRVTVKSLDYSRKLKNVLVTIYWLGKAANSCTSYSGTTLNLKEFEGLLAQMRKDTDDIESPKRSIRDSGYIDCWDSERSDSLSPPRHGRDDSFDSLDSFGSRSRQTPSPDVVLRGSSDGRGSDSESDLPHRKLPDVKKDDMSARRTSHGEPKSAVPFNQYLPNKSNQTAYVPAPLRKKKAEREEYRKSWSTATSPLGGERPFRYGPRTPVSDDAESTSMFDMRCEEEAAVQPHSRARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLIKKEEERKKMEKLLAGEDGTSERRKSIKTYREIVQEKERRERELHEAYKNARSQEEAEGILQQYIERFTISEAVLERLEMPKILERSHSTEPNLSSFLNDPNPMKYLRQQSLPPPKFTATVETTIARASVLDTSMSAGSGSPSKTVTPKAVPMLTPKPYSQPKNSQDVLKTFKVDGKVSVNGETVHREEEKERECPTVAPAHSLTKSQMFEGVARVHGSPLELKQDNGSIEINIKKPNSVPQELAATTEKTEPNSQEDKNDGGKSRKGNIELASSEPQHFTTTVTRCSPTVAFVEFPSSPQLKNDVSEEKDQKKPENEMSGKVELVLSQKVVKPKSPEPEATLTFPFLDKMPEANQLHLPNLNSQVDSPSSEKSPVMTPQFKFWAWDPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIEDTVVPFTVSSSSADQLSTSSSMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQGDDSDLLLKTRESDRLEEKGSLTEGALAHSGNPVSKGVHEDHQLDTEAGAPHCGTNPQLAQDPSQNQQTSNPTHSSEDVKPKTLPLDKSINHQIESPSERRKKSPREHFQAGPFSPCSPTPPGQSPNRSISGKKLCSSCGLPLGKGAAMIIETLNLYFHIQCFRCGICKGQLGDAVSGTDVRIRNGLLNCNDCYMRSRSAGQPTTL
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
5 (in isoform 3)Phosphorylation-17.7220068231
5 (in isoform 5)Phosphorylation-17.7220068231
5 (in isoform 7)Phosphorylation-17.7220068231
5 (in isoform 8)Phosphorylation-17.7220068231
10 (in isoform 3)Phosphorylation-19.2817081983
10 (in isoform 5)Phosphorylation-19.2817081983
10 (in isoform 7)Phosphorylation-19.2817081983
10 (in isoform 8)Phosphorylation-19.2817081983
15 (in isoform 6)Phosphorylation-47.1728348404
15 (in isoform 9)Phosphorylation-47.1728348404
25PhosphorylationPPPEPAFSEAQKWIE
CCCCCCCHHHHHHHH		33.8428851738
38PhosphorylationIEQVTGRSFGDKDFR
HHHHHCCCCCCHHHC		34.6220873877
95UbiquitinationGCKELGLKESQLFDP
HHHHHCCCHHHCCCH		54.22-
115UbiquitinationTSNRVTVKSLDYSRK
CCCCEEEECCHHHHH		35.62-
131PhosphorylationKNVLVTIYWLGKAAN
HHHEEEEEECHHHHH		5.8025332170
141PhosphorylationGKAANSCTSYSGTTL
HHHHHHCCCCCCCCC		30.4417081983
144PhosphorylationANSCTSYSGTTLNLK
HHHCCCCCCCCCCHH		29.4517081983
144 (in isoform 5)Phosphorylation-29.4529507054
149 (in isoform 9)Phosphorylation-47.1529507054
154 (in isoform 5)Phosphorylation-50.4522210691
155 (in isoform 5)Phosphorylation-31.1722210691
156 (in isoform 5)Phosphorylation-2.5622210691
159 (in isoform 9)Phosphorylation-31.9822210691
160 (in isoform 9)Phosphorylation-4.8422210691
161 (in isoform 9)Phosphorylation-22.9422210691
162MethylationGLLAQMRKDTDDIES
HHHHHHHCCCCCCCC		60.69116253997
164PhosphorylationLAQMRKDTDDIESPK
HHHHHCCCCCCCCCC		38.3129632367
169PhosphorylationKDTDDIESPKRSIRD
CCCCCCCCCCHHHHC		35.7329255136
171MethylationTDDIESPKRSIRDSG
CCCCCCCCHHHHCCC		68.97116254005
173PhosphorylationDIESPKRSIRDSGYI
CCCCCCHHHHCCCCC		28.2727251275
177PhosphorylationPKRSIRDSGYIDCWD
CCHHHHCCCCCCCCC		24.5228857561
179PhosphorylationRSIRDSGYIDCWDSE
HHHHCCCCCCCCCCC		9.5027251275
185PhosphorylationGYIDCWDSERSDSLS
CCCCCCCCCCCCCCC		15.4821815630
188PhosphorylationDCWDSERSDSLSPPR
CCCCCCCCCCCCCCC		27.7429396449
190PhosphorylationWDSERSDSLSPPRHG
CCCCCCCCCCCCCCC		31.8025159151
192PhosphorylationSERSDSLSPPRHGRD
CCCCCCCCCCCCCCC		36.4929255136
201PhosphorylationPRHGRDDSFDSLDSF
CCCCCCCCCCCCCCC		34.9322167270
204PhosphorylationGRDDSFDSLDSFGSR
CCCCCCCCCCCCCCC		31.8722167270
207PhosphorylationDSFDSLDSFGSRSRQ
CCCCCCCCCCCCCCC		36.4821082442
210PhosphorylationDSLDSFGSRSRQTPS
CCCCCCCCCCCCCCC		25.6822617229
212PhosphorylationLDSFGSRSRQTPSPD
CCCCCCCCCCCCCCC		30.3625463755
215PhosphorylationFGSRSRQTPSPDVVL
CCCCCCCCCCCCEEE		25.3229255136
217PhosphorylationSRSRQTPSPDVVLRG
CCCCCCCCCCEEECC		36.8029255136
225PhosphorylationPDVVLRGSSDGRGSD
CCEEECCCCCCCCCC		20.8722167270
226PhosphorylationDVVLRGSSDGRGSDS
CEEECCCCCCCCCCC		47.0822167270
231PhosphorylationGSSDGRGSDSESDLP
CCCCCCCCCCCCCCC		36.2829255136
233PhosphorylationSDGRGSDSESDLPHR
CCCCCCCCCCCCCCC		40.4729255136
235PhosphorylationGRGSDSESDLPHRKL
CCCCCCCCCCCCCCC		48.6922167270
251PhosphorylationDVKKDDMSARRTSHG
CCCHHCCHHCCCCCC		26.1429514088
255PhosphorylationDDMSARRTSHGEPKS
HCCHHCCCCCCCCCC		21.3729514088
256PhosphorylationDMSARRTSHGEPKSA
CCHHCCCCCCCCCCC		27.9029514088
262PhosphorylationTSHGEPKSAVPFNQY
CCCCCCCCCCCHHHC		45.2628555341
263 (in isoform 3)Phosphorylation-21.0926437602
269PhosphorylationSAVPFNQYLPNKSNQ
CCCCHHHCCCCCCCC		25.8221945579
274PhosphorylationNQYLPNKSNQTAYVP
HHCCCCCCCCCEECC		40.5919060867
277PhosphorylationLPNKSNQTAYVPAPL
CCCCCCCCEECCCCH		24.9819060867
279PhosphorylationNKSNQTAYVPAPLRK
CCCCCCEECCCCHHC		15.4527642862
294PhosphorylationKKAEREEYRKSWSTA
CHHHHHHHHHHHCCC		20.7024719451
297PhosphorylationEREEYRKSWSTATSP
HHHHHHHHHCCCCCC		19.7730266825
299PhosphorylationEEYRKSWSTATSPLG
HHHHHHHCCCCCCCC		18.4330266825
300PhosphorylationEYRKSWSTATSPLGG
HHHHHHCCCCCCCCC		27.9130266825
302PhosphorylationRKSWSTATSPLGGER
HHHHCCCCCCCCCCC		30.8530266825
303PhosphorylationKSWSTATSPLGGERP
HHHCCCCCCCCCCCC		18.7030266825
303 (in isoform 4)Phosphorylation-18.7029507054
312 (in isoform 3)Phosphorylation-37.8827067055
313PhosphorylationGGERPFRYGPRTPVS
CCCCCCCCCCCCCCC		31.6822199227
313 (in isoform 4)Phosphorylation-31.6822210691
314 (in isoform 4)Phosphorylation-10.8522210691
315 (in isoform 3)Phosphorylation-28.2127067055
315 (in isoform 4)Phosphorylation-28.2122210691
317PhosphorylationPFRYGPRTPVSDDAE
CCCCCCCCCCCCCCC		31.0422199227
320PhosphorylationYGPRTPVSDDAESTS
CCCCCCCCCCCCCCC		30.8622199227
325PhosphorylationPVSDDAESTSMFDMR
CCCCCCCCCCCCCCC		27.7423312004
326PhosphorylationVSDDAESTSMFDMRC
CCCCCCCCCCCCCCC		18.7321815630
327PhosphorylationSDDAESTSMFDMRCE
CCCCCCCCCCCCCCC		27.0821815630
338 (in isoform 3)Phosphorylation-12.0826437602
377PhosphorylationRWKSRRRSVSQDLIK
HHHHHHHHHHHHHHH		25.0625463755
379PhosphorylationKSRRRSVSQDLIKKE
HHHHHHHHHHHHHHH		21.1525159151
402PhosphorylationLLAGEDGTSERRKSI
HHCCCCCCHHHHHHH		39.4721815630
403PhosphorylationLAGEDGTSERRKSIK
HCCCCCCHHHHHHHH		34.3423186163
408PhosphorylationGTSERRKSIKTYREI
CCHHHHHHHHHHHHH		27.75-
412PhosphorylationRRKSIKTYREIVQEK
HHHHHHHHHHHHHHH		10.97-
419MalonylationYREIVQEKERREREL
HHHHHHHHHHHHHHH		39.1626320211
434 (in isoform 3)Phosphorylation-48.5520068231
435PhosphorylationEAYKNARSQEEAEGI
HHHHHHCCHHHHHHH		39.2629507054
437 (in isoform 3)Phosphorylation-61.4920068231
446PhosphorylationAEGILQQYIERFTIS
HHHHHHHHHHHHCCC		7.5627642862
469PhosphorylationMPKILERSHSTEPNL
CHHHHHCCCCCCCCH		16.6525463755
471PhosphorylationKILERSHSTEPNLSS
HHHHCCCCCCCCHHH		35.3925463755
472PhosphorylationILERSHSTEPNLSSF
HHHCCCCCCCCHHHH		50.4622167270
477PhosphorylationHSTEPNLSSFLNDPN
CCCCCCHHHHHCCCC		26.1921712546
478PhosphorylationSTEPNLSSFLNDPNP
CCCCCHHHHHCCCCH		36.6023663014
486 (in isoform 3)Phosphorylation-5.9126437602
493O-linked_GlycosylationMKYLRQQSLPPPKFT
HHHHHHCCCCCCCCC		34.2131373491
493PhosphorylationMKYLRQQSLPPPKFT
HHHHHHCCCCCCCCC		34.2125159151
500O-linked_GlycosylationSLPPPKFTATVETTI
CCCCCCCCEEEEEEE		27.7831373491
500PhosphorylationSLPPPKFTATVETTI
CCCCCCCCEEEEEEE		27.7820068231
502O-linked_GlycosylationPPPKFTATVETTIAR
CCCCCCEEEEEEEEE		18.8031373491
502PhosphorylationPPPKFTATVETTIAR
CCCCCCEEEEEEEEE		18.8020068231
505PhosphorylationKFTATVETTIARASV
CCCEEEEEEEEEHHH		21.1120068231
506O-linked_GlycosylationFTATVETTIARASVL
CCEEEEEEEEEHHHH		10.1131373491
506PhosphorylationFTATVETTIARASVL
CCEEEEEEEEEHHHH		10.1120068231
511PhosphorylationETTIARASVLDTSMS
EEEEEEHHHHHCCCC		20.0523403867
515PhosphorylationARASVLDTSMSAGSG
EEHHHHHCCCCCCCC		23.3625159151
516PhosphorylationRASVLDTSMSAGSGS
EHHHHHCCCCCCCCC		15.4825159151
518PhosphorylationSVLDTSMSAGSGSPS
HHHHCCCCCCCCCCC		29.2825159151
521PhosphorylationDTSMSAGSGSPSKTV
HCCCCCCCCCCCCCC		35.5029255136
523PhosphorylationSMSAGSGSPSKTVTP
CCCCCCCCCCCCCCC		27.9129255136
525PhosphorylationSAGSGSPSKTVTPKA
CCCCCCCCCCCCCCC		42.5329255136
526 (in isoform 6)O-linked_Glycosylation-50.8531373491
527PhosphorylationGSGSPSKTVTPKAVP
CCCCCCCCCCCCCCC		33.6718669648
529PhosphorylationGSPSKTVTPKAVPML
CCCCCCCCCCCCCCC		25.0518669648
537PhosphorylationPKAVPMLTPKPYSQP
CCCCCCCCCCCCCCC		24.0225159151
541PhosphorylationPMLTPKPYSQPKNSQ
CCCCCCCCCCCCCCC		26.5120068231
542PhosphorylationMLTPKPYSQPKNSQD
CCCCCCCCCCCCCCC		48.8320068231
547PhosphorylationPYSQPKNSQDVLKTF
CCCCCCCCCCHHHHE		33.6117081983
553PhosphorylationNSQDVLKTFKVDGKV
CCCCHHHHEEECCEE		25.24-
561PhosphorylationFKVDGKVSVNGETVH
EEECCEEEECCEEEE		17.2228555341
566PhosphorylationKVSVNGETVHREEEK
EEEECCEEEEHHHHH		24.02-
580 (in isoform 9)Phosphorylation-3.4730206219
584 (in isoform 9)Phosphorylation-23.4522167270
585PhosphorylationPTVAPAHSLTKSQMF
CCCCCCCCCCHHHHH		39.5825159151
586 (in isoform 9)Phosphorylation-5.1222167270
587PhosphorylationVAPAHSLTKSQMFEG
CCCCCCCCHHHHHCC		31.5025159151
587 (in isoform 8)Phosphorylation-31.5030206219
587 (in isoform 9)Phosphorylation-31.5026657352
588MethylationAPAHSLTKSQMFEGV
CCCCCCCHHHHHCCE		43.94115972519
588UbiquitinationAPAHSLTKSQMFEGV
CCCCCCCHHHHHCCE		43.94-
589PhosphorylationPAHSLTKSQMFEGVA
CCCCCCHHHHHCCEE		22.9525159151
590 (in isoform 9)Phosphorylation-41.9822167270
591 (in isoform 8)Phosphorylation-4.2222167270
592 (in isoform 6)Phosphorylation-5.9930206219
593 (in isoform 8)Phosphorylation-47.6322167270
594 (in isoform 8)Phosphorylation-13.7126657352
594 (in isoform 9)Phosphorylation-13.7122167270
596 (in isoform 6)Phosphorylation-20.7322167270
597 (in isoform 8)Phosphorylation-20.6822167270
598 (in isoform 6)Phosphorylation-4.2922167270
599 (in isoform 6)Phosphorylation-26.0126657352
601PhosphorylationGVARVHGSPLELKQD
CEEEECCCCEEEECC		16.0722167270
601 (in isoform 5)Phosphorylation-16.0722617229
601 (in isoform 8)Phosphorylation-16.0722167270
602 (in isoform 6)Phosphorylation-34.1522167270
606 (in isoform 6)Phosphorylation-46.3522167270
610 (in isoform 5)Phosphorylation-37.9921815630
611PhosphorylationELKQDNGSIEINIKK
EEECCCCCEEEEEEC		24.2526437602
614 (in isoform 5)Phosphorylation-6.5228102081
621PhosphorylationINIKKPNSVPQELAA
EEEECCCCCCHHHHC		43.6426657352
629PhosphorylationVPQELAATTEKTEPN
CCHHHHCCCCCCCCC		29.8528555341
630PhosphorylationPQELAATTEKTEPNS
CHHHHCCCCCCCCCC		30.6629214152
637PhosphorylationTEKTEPNSQEDKNDG
CCCCCCCCCCCCCCC		45.7429214152
641AcetylationEPNSQEDKNDGGKSR
CCCCCCCCCCCCCCC		57.0726051181
656PhosphorylationKGNIELASSEPQHFT
CCCEEECCCCCCCEE		48.1029514088
657O-linked_GlycosylationGNIELASSEPQHFTT
CCEEECCCCCCCEEE		47.9231373491
657PhosphorylationGNIELASSEPQHFTT
CCEEECCCCCCCEEE		47.9230576142
662 (in isoform 3)Phosphorylation-5.6717081983
663PhosphorylationSSEPQHFTTTVTRCS
CCCCCCEEEEEEEEC		21.3129514088
664PhosphorylationSEPQHFTTTVTRCSP
CCCCCEEEEEEEECC		20.5129514088
665PhosphorylationEPQHFTTTVTRCSPT
CCCCEEEEEEEECCE		19.4729514088
667PhosphorylationQHFTTTVTRCSPTVA
CCEEEEEEEECCEEE		24.7025159151
670PhosphorylationTTTVTRCSPTVAFVE
EEEEEEECCEEEEEE		21.9522167270
672PhosphorylationTVTRCSPTVAFVEFP
EEEEECCEEEEEECC		14.2625463755
680PhosphorylationVAFVEFPSSPQLKND
EEEEECCCCHHHCCC		61.0325463755
681PhosphorylationAFVEFPSSPQLKNDV
EEEECCCCHHHCCCC		19.5325463755
698 (in isoform 3)Phosphorylation-74.77-
702 (in isoform 3)Phosphorylation-29.32-
705 (in isoform 3)Phosphorylation-8.63-
710PhosphorylationGKVELVLSQKVVKPK
CCEEEEEEEECCCCC		22.0725159151
718PhosphorylationQKVVKPKSPEPEATL
EECCCCCCCCCCCEE		42.9219664994
724PhosphorylationKSPEPEATLTFPFLD
CCCCCCCEEECCHHH		25.3525463755
726PhosphorylationPEPEATLTFPFLDKM
CCCCCEEECCHHHCC		25.5522617229
746PhosphorylationLHLPNLNSQVDSPSS
CCCCCCCCCCCCCCC		34.4422199227
746 (in isoform 10)Phosphorylation-34.4430206219
750PhosphorylationNLNSQVDSPSSEKSP
CCCCCCCCCCCCCCC		28.0225159151
750 (in isoform 10)Phosphorylation-28.0222167270
752PhosphorylationNSQVDSPSSEKSPVM
CCCCCCCCCCCCCCC		55.8930619164
752 (in isoform 10)Phosphorylation-55.8922167270
753PhosphorylationSQVDSPSSEKSPVMT
CCCCCCCCCCCCCCC		53.0520068231
753 (in isoform 10)Phosphorylation-53.0526657352
756PhosphorylationDSPSSEKSPVMTPQF
CCCCCCCCCCCCCCC		20.7625159151
756 (in isoform 10)Phosphorylation-20.7622167270
760PhosphorylationSEKSPVMTPQFKFWA
CCCCCCCCCCCCEEE		17.7425599653
760 (in isoform 10)Phosphorylation-17.7422167270
760 (in isoform 4)Phosphorylation-17.7422617229
769 (in isoform 4)Phosphorylation-32.7421815630
773 (in isoform 4)Phosphorylation-50.2328102081
799 (in isoform 9)Phosphorylation-13.0425159151
806 (in isoform 8)Phosphorylation-17.7325159151
806 (in isoform 9)Phosphorylation-17.7329743597
808 (in isoform 9)Phosphorylation-69.4629116813
811 (in isoform 6)Phosphorylation-61.8625159151
813 (in isoform 8)Phosphorylation-43.2129743597
815 (in isoform 8)Phosphorylation-34.8729116813
818 (in isoform 6)Phosphorylation-18.3029743597
819 (in isoform 5)Phosphorylation-44.4325159151
820 (in isoform 6)Phosphorylation-47.1629116813
826 (in isoform 5)Phosphorylation-51.6129743597
828 (in isoform 5)Phosphorylation-15.6029116813
833PhosphorylationEDTVVPFTVSSSSAD
HCCEEEEEECCCCCH		17.2627251275
835PhosphorylationTVVPFTVSSSSADQL
CEEEEEECCCCCHHH		22.8027251275
836PhosphorylationVVPFTVSSSSADQLS
EEEEEECCCCCHHHC		24.7927251275
837PhosphorylationVPFTVSSSSADQLST
EEEEECCCCCHHHCC		23.2627251275
838PhosphorylationPFTVSSSSADQLSTS
EEEECCCCCHHHCCC		37.5027251275
843PhosphorylationSSSADQLSTSSSMTE
CCCCHHHCCCCCCCC		22.1727251275
844PhosphorylationSSADQLSTSSSMTEG
CCCHHHCCCCCCCCC		41.0230576142
845PhosphorylationSADQLSTSSSMTEGS
CCHHHCCCCCCCCCC		19.6230576142
846PhosphorylationADQLSTSSSMTEGSG
CHHHCCCCCCCCCCC		24.9827251275
847PhosphorylationDQLSTSSSMTEGSGT
HHHCCCCCCCCCCCC		29.5027251275
854PhosphorylationSMTEGSGTMNKIDLG
CCCCCCCCCCEEECC		21.1930576142
875PhosphorylationQDRRWKKSFQGDDSD
HHHHHHHHHCCCCCC		21.0525159151
881PhosphorylationKSFQGDDSDLLLKTR
HHHCCCCCCEEEHHH		34.5926330541
886UbiquitinationDDSDLLLKTRESDRL
CCCCEEEHHHHHHHC		45.57-
887PhosphorylationDSDLLLKTRESDRLE
CCCEEEHHHHHHHCH		39.3722798277
898PhosphorylationDRLEEKGSLTEGALA
HHCHHCCCCCHHHHH		43.0925159151
900PhosphorylationLEEKGSLTEGALAHS
CHHCCCCCHHHHHCC		33.7920068231
907PhosphorylationTEGALAHSGNPVSKG
CHHHHHCCCCCCCCC		34.3625159151
912PhosphorylationAHSGNPVSKGVHEDH
HCCCCCCCCCCCCCC		25.5823312004
932PhosphorylationAGAPHCGTNPQLAQD
CCCCCCCCCHHHCCC		49.47-
965 (in isoform 10)Phosphorylation-62.0025159151
966PhosphorylationKTLPLDKSINHQIES
CCCCCCHHHCCCCCC		28.4329255136
966 (in isoform 2)Phosphorylation-28.4325159151
972 (in isoform 10)Phosphorylation-50.4529743597
973PhosphorylationSINHQIESPSERRKK
HHCCCCCCHHHHHCC		35.0429255136
973 (in isoform 2)Phosphorylation-35.0429743597
974 (in isoform 10)Phosphorylation-27.6729116813
975PhosphorylationNHQIESPSERRKKSP
CCCCCCHHHHHCCCH		53.6830266825
975 (in isoform 2)Phosphorylation-53.6829116813
978 (in isoform 4)Phosphorylation-46.8625159151
981PhosphorylationPSERRKKSPREHFQA
HHHHHCCCHHHHHCC		32.02-
985 (in isoform 4)Phosphorylation-22.7729743597
987 (in isoform 4)Phosphorylation-47.5229116813
992PhosphorylationHFQAGPFSPCSPTPP
HHCCCCCCCCCCCCC		28.2926437602
995PhosphorylationAGPFSPCSPTPPGQS
CCCCCCCCCCCCCCC		34.8826437602
1015PhosphorylationSGKKLCSSCGLPLGK
CCCCHHHHCCCCCCC		15.9418669648
1054PhosphorylationGQLGDAVSGTDVRIR
CCCCCCCCCCCEEEC		37.3827251275
1056PhosphorylationLGDAVSGTDVRIRNG
CCCCCCCCCEEECCC		24.6627251275
1076PhosphorylationDCYMRSRSAGQPTTL
CCCCCCCCCCCCCCC		37.6928555341
1131 (in isoform 3)Phosphorylation-30206219
1135 (in isoform 3)Phosphorylation-22167270
1137 (in isoform 3)Phosphorylation-22167270
1138 (in isoform 3)Phosphorylation-26657352
1141 (in isoform 3)Phosphorylation-22167270
1145 (in isoform 3)Phosphorylation-22167270
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of LIMC1_HUMAN !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of LIMC1_HUMAN !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of LIMC1_HUMAN !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
A4_HUMANAPPphysical
21832049
CUTC_HUMANCUTCphysical
22863883
DBLOH_HUMANDIABLOphysical
22863883
GABPA_HUMANGABPAphysical
22863883
IMA5_HUMANKPNA1physical
22863883
NPM_HUMANNPM1physical
22863883
TRM61_HUMANTRMT61Aphysical
22863883
KLH15_HUMANKLHL15physical
26186194
RFC2_HUMANRFC2physical
26186194
YES_HUMANYES1physical
26186194
NAGK_HUMANNAGKphysical
26186194
GBB4_HUMANGNB4physical
26186194
KLH15_HUMANKLHL15physical
28514442
Drug and Disease Associations
Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of LIMC1_HUMAN

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Related Literatures of Post-Translational Modification
Phosphorylation
ReferencePubMed
"Lys-N and trypsin cover complementary parts of the phosphoproteome ina refined SCX-based approach.";
Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J.,Mohammed S.;
Anal. Chem. 81:4493-4501(2009).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-718, AND MASSSPECTROMETRY.
"A quantitative atlas of mitotic phosphorylation.";
Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E.,Elledge S.J., Gygi S.P.;
Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-192; THR-215; SER-217;SER-225; SER-231; SER-233; SER-377; SER-471; SER-516; SER-521;SER-523; THR-529; SER-601; SER-718; SER-875 AND SER-973, AND MASSSPECTROMETRY.
"A probability-based approach for high-throughput proteinphosphorylation analysis and site localization.";
Beausoleil S.A., Villen J., Gerber S.A., Rush J., Gygi S.P.;
Nat. Biotechnol. 24:1285-1292(2006).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-192; SER-493 ANDSER-718, AND MASS SPECTROMETRY.
"Global, in vivo, and site-specific phosphorylation dynamics insignaling networks.";
Olsen J.V., Blagoev B., Gnad F., Macek B., Kumar C., Mortensen P.,Mann M.;
Cell 127:635-648(2006).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-169; SER-201; SER-204;SER-207; SER-210; SER-212; THR-215; SER-217; SER-274; THR-277;SER-377; SER-718 AND SER-973, AND MASS SPECTROMETRY.

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