LHTL8_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: LHTL8_ARATH
• UniProt AC: Q9SX98
• Protein Name: Lysine histidine transporter-like 8
• Gene Name: AATL1
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 519
• Subcellular Localization: Cell membrane ; Multi-pass membrane protein .
• Protein Description: Amino acid transporter..
• Protein Sequence: MDERPETELISIPATPRVSTPEILTPSGQRSPRPATKPSSATWTPTSFISPRFLSPIGTPMKRVLVNMKGYLEEVGHLTKLNPQDAWLPITESRNGNAHYAAFHNLNAGVGFQALVLPVAFAFLGWSWGILSLTIAYCWQLYTLWILVQLHEAVPGKRYNRYVELAQAAFGERLGVWLALFPTVYLSAGTATALILIGGETMKLFFQIVCGPLCTSNPLTTVEWYLVFTSLCIVLSQLPNLNSIAGLSLIGAVTAITYSTMVWVLSVSQPRPATISYEPLSMPSTSGSLFAVLNALGIIAFAFRGHNLVLEIQSTMPSTFKHPAHVPMWRGAKISYFLIALCIFPISIGGFWAYGNLMPSGGMLAALYAFHIHDIPRGLLATAFLLVVFSCLSSFQIYSMPAFDSFEAGYTSRTNKPCSIWVRSGFRVFFGFVSFFIGVALPFLSSLAGLLGGLTLPVTFAYPCFMWVLIKKPAKYSFNWYFHWGLGWLGVAFSLAFSIGGIWSMVTNGLKLKFFKPPN

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
7	Phosphorylation	-MDERPETELISIPA -CCCCCCCEEEECCC	38.48	30407730
11	Phosphorylation	RPETELISIPATPRV CCCCEEEECCCCCCC	34.83	30407730
15	Phosphorylation	ELISIPATPRVSTPE EEEECCCCCCCCCCC	13.28	30407730
19	Phosphorylation	IPATPRVSTPEILTP CCCCCCCCCCCCCCC	39.25	15308754
20	Phosphorylation	PATPRVSTPEILTPS CCCCCCCCCCCCCCC	23.29	15308754
25	Phosphorylation	VSTPEILTPSGQRSP CCCCCCCCCCCCCCC	22.52	19880383
27	Phosphorylation	TPEILTPSGQRSPRP CCCCCCCCCCCCCCC	42.18	30407730
31	Phosphorylation	LTPSGQRSPRPATKP CCCCCCCCCCCCCCC	19.85	30407730
55	Phosphorylation	FISPRFLSPIGTPMK CCCHHHCCCCCCCCH	16.26	17317660
59	Phosphorylation	RFLSPIGTPMKRVLV HHCCCCCCCCHHHHH	22.41	17317660

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of LHTL8_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of LHTL8_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of LHTL8_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
PLST4_ARATH	PGLCT	physical	22737156
PRA1C_ARATH	PRA1.C	physical	24833385
PIP15_ARATH	PIP1;5	physical	24833385
PTR14_ARATH	NRT1.5	physical	24833385
HHP4_ARATH	HHP4	physical	24833385
HHP2_ARATH	HHP2	physical	24833385
UBC34_ARATH	UBC34	physical	24833385
UBC32_ARATH	UBC32	physical	24833385
UTR3_ARATH	UTR3	physical	24833385
TRXH5_ARATH	TRX5	physical	24833385
AGP27_ARATH	AGP27	physical	24833385
CNIH1_ARATH	AT3G12180	physical	24833385
HSDD3_ARATH	AT2G43420	physical	24833385
CP21D_ARATH	AT3G66654	physical	24833385
BET12_ARATH	ATBET12	physical	24833385
MMGT_ARATH	AT5G03345	physical	24833385

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Phosphorylation

"Phosphoproteomics of the Arabidopsis plasma membrane and a newphosphorylation site database.";
Nuehse T.S., Stensballe A., Jensen O.N., Peck S.C.;
Plant Cell 16:2394-2405(2004).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-19 AND THR-25, MASSSPECTROMETRY, AND SUBCELLULAR LOCATION.
PubMed: 15308754