JING_DROME - dbPTM
JING_DROME - PTM Information in dbPTM
Basic Information of Protein
UniProt ID JING_DROME
UniProt AC Q7KHG2
Protein Name Zinc finger protein jing
Gene Name jing
Organism Drosophila melanogaster (Fruit fly).
Sequence Length 1486
Subcellular Localization Nucleus .
Protein Description May functionally interact with Polycomb group (PcG) and trithorax group (trxG) proteins to repress transcription (Probable). Required for Egfr pathway function and MAPK activity in CNS midline and tracheal placodes and for CNS axon development and tracheal tubule development. Required to establish the primary axon scaffold in the brain and for lateral positioning of longitudinal glia, longitudinal axons and neurons. Required for glial survival. Required to establish the proximo-distal axis of the developing leg and for wing vein and alula development. Required for regenerative growth in leg imaginal disks. Required for the initiation of anterior migration of border cells of the ovary..
Protein Sequence MPPHILGSASGSSSTAAASPPTSSASQTPPSPAIHHSHLSQHNATSAMSKPTTPQRHGNPSLLPTLQWPWNTSLGSTSTAVPAASANKNKRTAAGSGAALGLSGEGSCLTGGGAASAKKARSDLPGSFDASKRLKVAAMEESQTKITGFFKSQMKPSPGGGKLSPQPGQQSNPANTLTMSTPATTASLNKYFNILSQLKEQKAQQQQQQQQASKTLPTPAPVAPVPSAPPVAPVVVTPSPSLPVPALKKIERSNKQPAKIAQVAPNLRKTPSSGSSGSSSSSSSSSSNGSNTGKSPTKKHVAIAPRTPEMKQQQQQGKAAMVYRPPVTSTALKQKQISPPAPVAAHTPAPAPALNPTPAPANPTLYQLPVQLPNLVQLPPQLAAAANIMQLNNVAKAAVAAAATNNAAAQAAQAAQAAAAQYFLNGTVFKLQQVTTATTTTATTATAAAAPAGNPFGLLNLATAGNPFGLPNANGQFPIEAIPGAGSYLHHQLLLARQNNMSLNETMASNSCGNMNFVNPLNNQQVGLKDNKLYIVNSAEYLGYLMSLQIALNNQQHQQQQIISATQPPPLAATNNNSTNTATQPPPLAATNNTNSNTANNSTASNSINHNASNNLSNINNTAIQPQRAIVKPPLHSSTQPPPLVTISSMPACSPAAASSPAAKRSLPAAKPYQKRLTAKGRVGTAPIIATPTTPPPLVPTSATKELGQLRKSTGTTGTPTGTPTPTPPLVSIAPSKLTPTLSVSKQGPTMKLANSAPDLFDLVKNSKLVAKVSQPLTPLPFSSPSSSSNGSHGSHGMRSSPALSTSNSCTLSAFSKIKVETTELASQTGSLTSSSIPTISLKPQSFAGQLPKREPESETDTLKHDLLPDCTNSNSNSNSCSSSTYSHSVSSAADLSLEASTPAPSPSPSASPSGLGSPSPAASNLSASSRRAASQTDMLSELVTSSCISSGGDDCSQATDSPPMPALPLAKSEDATTPISTVSGGSSSGSSNYDEEDDKSVASLETHQTHKRLRDLPTPESGIGGSLSNSESSNSIADAISSKSASVGPPTTAASSASSSASDSNSLASNAPSPASPEDCSAAPSPACSASTTGSIPPSTVVDIAMVEATSKSLPKSAISPILSQPKTIRFPAGAGASGKGGKRHDGVCYWDKCNKKHESNSKLLDHMQTHHVNTQTGPFACLWVGCKVYNKESCSRRWLERHVLSHGGSKQFKCIVEGCGLRFGSQLALQKHVNNHFNATDNARESTSKRTSDPPVPKQLRKNGKKLRYRRQPFSARMFDFFDTGIMEGLQHRLRQISTLTNGAQAIEFQGQCMMRRRNSQGGYECFVRWSPREIISDEWLPECLNRTRQHTKVLHIKQMRPAEKTRVDSLLSTAFRLRYDSHLFADDYNVNEQQVGEASGSDCDEDGDGDQEEEDLEDQDEDEEEDGSSSSRSASCETVSSYQQVLSIAKLQMQQRRKHPRKPPKVTPPAREKLVPTDALVPI
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster

Oops, there are no PTM records of JING_DROME !!

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of JING_DROME !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of JING_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of JING_DROME !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
SLIT_DROMEsligenetic
12015288
TRH_DROMEtrhgenetic
12015288
SIM_DROMEsimgenetic
12015288
CEBP_DROMEslbogenetic
11152631
ARNT_DROMEtgogenetic
12015288
FGFR2_DROMEbtlgenetic
12015288
STAR_DROMESgenetic
15511644
SPITZ_DROMEspigenetic
15511644
EGFR_DROMEEgfrgenetic
15511644
RAS1_DROMERas85Dgenetic
15511644
ATRX_DROMEXNPgenetic
16648585

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of JING_DROME

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Related Literatures of Post-Translational Modification

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