| UniProt ID | HPDL_HUMAN | |
|---|---|---|
| UniProt AC | Q96IR7 | |
| Protein Name | 4-hydroxyphenylpyruvate dioxygenase-like protein | |
| Gene Name | HPDL | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 371 | |
| Subcellular Localization | ||
| Protein Description | May have dioxygenase activity.. | |
| Protein Sequence | MAAPALRLCHIAFHVPAGQPLARNLQRLFGFQPLASREVDGWRQLALRSGDAVFLVNEGAGSGEPLYGLDPRHAVPSATNLCFDVADAGAATRELAALGCSVPVPPVRVRDAQGAATYAVVSSPAGILSLTLLERAGYRGPFLPGFRPVSSAPGPGWVSRVDHLTLACTPGSSPTLLRWFHDCLGFCHLPLSPGEDPELGLEMTAGFGLGGLRLTALQAQPGSIVPTLVLAESLPGATTRQDQVEQFLARHKGPGLQHVGLYTPNIVEATEGVATAGGQFLAPPGAYYQQPGKERQIRAAGHEPHLLARQGILLDGDKGKFLLQVFTKSLFTEDTFFLELIQRQGATGFGQGNIRALWQSVQEQSARSQEA | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 173 | Phosphorylation | LACTPGSSPTLLRWF EEECCCCCHHHHHHH | 28.02 | 23403867 | |
| 175 | Phosphorylation | CTPGSSPTLLRWFHD ECCCCCHHHHHHHHH | 40.13 | 23403867 | |
| 262 | Phosphorylation | GLQHVGLYTPNIVEA CCEEEEEECCCHHHC | 17.77 | - | |
| 318 | Ubiquitination | GILLDGDKGKFLLQV CEEEECCCHHHHHHH | 70.32 | 29967540 | |
| 327 | Phosphorylation | KFLLQVFTKSLFTED HHHHHHHHHHHCCCC | 22.37 | 20068231 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of HPDL_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of HPDL_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of HPDL_HUMAN !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| MPRD_HUMAN | M6PR | physical | 22939629 | |
| STMN1_HUMAN | STMN1 | physical | 22939629 | |
| SUCB1_HUMAN | SUCLA2 | physical | 22939629 | |
| TM177_HUMAN | TMEM177 | physical | 22939629 | |
| TACO1_HUMAN | TACO1 | physical | 22939629 | |
| TCOF_HUMAN | TCOF1 | physical | 22939629 | |
| LSM12_HUMAN | LSM12 | physical | 22939629 | |
| HTRA2_HUMAN | HTRA2 | physical | 22939629 | |
| RIF1_HUMAN | RIF1 | physical | 22939629 | |
| THTR_HUMAN | TST | physical | 22939629 | |
| NUSAP_HUMAN | NUSAP1 | physical | 22939629 | |
| MECP2_HUMAN | MECP2 | physical | 22939629 | |
| HYEP_HUMAN | EPHX1 | physical | 22939629 | |
| TOIP1_HUMAN | TOR1AIP1 | physical | 22939629 |
| Kegg Disease | ||||||
|---|---|---|---|---|---|---|
| There are no disease associations of PTM sites. | ||||||
| OMIM Disease | ||||||
| There are no disease associations of PTM sites. | ||||||
| Kegg Drug | ||||||
| There are no disease associations of PTM sites. | ||||||
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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