GRH1_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: GRH1_ARATH
• UniProt AC: Q9ZR12
• Protein Name: GRR1-like protein 1
• Gene Name: GRH1
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 585
• Subcellular Localization: Nucleus .
• Protein Description: Component of SCF(ASK-cullin-F-box) E3 ubiquitin ligase complexes, which may mediate the ubiquitination and subsequent proteasomal degradation of target proteins. Auxin receptor that mediates Aux/IAA proteins proteasomal degradation and auxin-regulated transcription. Involved in embryogenesis regulation by auxin. Confers sensitivity to the virulent bacterial pathogen P.syringae. Mediates glucose repression in yeast..
• Protein Sequence: MGLRFPPKVLEHILSFIDSNEDRNSVSLVCKSWFETERKTRKRVFVGNCYAVSPAAVTRRFPEMRSLTLKGKPHFADYNLVPDGWGGYAWPWIEAMAAKSSSLEEIRMKRMVVTDECLEKIAASFKDFKVLVLTSCEGFSTDGIAAIAATCRNLRVLELRECIVEDLGGDWLSYFPESSTSLVSLDFSCLDSEVKISDLERLVSRSPNLKSLKLNPAVTLDGLVSLLRCAPQLTELGTGSFAAQLKPEAFSKLSEAFSNCKQLQSLSGLWDVLPEYLPALYSVCPGLTSLNLSYATVRMPDLVELLRRCSKLQKLWVMDLIEDKGLEAVASYCKELRELRVFPSEPDLDATNIPLTEQGLVFVSKGCRKLESVLYFCVQFTNAALFTIARKRPNLKCFRLCVIEPFAPDYKTNEPLDKGFKAIAEGCRDLRRLSVSGLLSDKAFKYIGKHAKKVRMLSIAFAGDSDLMLHHLLSGCESLKKLEIRDCPFGDTALLEHAAKLETMRSLWMSSCFVSFGACKLLSQKMPRLNVEVIDEHPPESRPESSPVERIYIYRTVAGPRMDTPEFVWTIHKNPENGVSHLAIK

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
434	Phosphorylation	CRDLRRLSVSGLLSD CHHHHHCCHHHHCCH	16.66	25561503

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of GRH1_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of GRH1_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of GRH1_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
SKP1A_ARATH	SKP1	physical	12008900
SKP1B_ARATH	ASK2	physical	12008900
IAA3_ARATH	SHY2	physical	22466420
IAA5_ARATH	IAA5	physical	22466420
IAA8_ARATH	IAA8	physical	22466420
IAA7_ARATH	IAA7	physical	22466420
IAA29_ARATH	IAA29	physical	22466420
IAA28_ARATH	IAA28	physical	21734647

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.