FZR2_ARATH - dbPTM
FZR2_ARATH - PTM Information in dbPTM
Basic Information of Protein
UniProt ID FZR2_ARATH
UniProt AC Q8L3Z8
Protein Name Protein FIZZY-RELATED 2
Gene Name FZR2
Organism Arabidopsis thaliana (Mouse-ear cress).
Sequence Length 483
Subcellular Localization Nucleus .
Protein Description Activator protein that regulates the ubiquitin ligase activity and substrate specificity of the anaphase promoting complex/cyclosome (APC/C). Necessary and sufficient for endoreduplication and correct cell expansion. Controls meristem size by stimulating endoreduplication in the elongation zone..
Protein Sequence MEEEDPTASNVITNSNSSSMRNLSPAMNTPVVSLESRINRLINANQSQSPSPSSLSRSIYSDRFIPSRSGSNFALFDLSPSPSKDGKEDGAGSYATLLRAAMFGPETPEKRDITGFSSSRNIFRFKTETHRSLNSFSPFGVDDDSPGVSHSGPVKAPRKVPRSPYKVLDAPALQDDFYLNLVDWSAQNVLAVGLGNCVYLWNACSSKVTKLCDLGAEDSVCSVGWALRGTHLAVGTSTGKVQIWDASRCKRTRTMEGHRLRVGALAWGSSVLSSGSRDKSILQRDIRCQEDHVSKLAGHKSEVCGLKWSYDNRELASGGNDNRLFVWNQHSTQPVLKYSEHTAAVKAIAWSPHVHGLLASGGGTADRCIRFWNTTTNTHLSSIDTCSQVCNLAWSKNVNELVSTHGYSQNQIIVWKYPTMSKIATLTGHTYRVLYLAVSPDGQTIVTGAGDETLRFWNVFPSPKSQNTDSEIGSSFFGRTTIR
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
58PhosphorylationSPSSLSRSIYSDRFI
CCCHHHHHHHCCCCC
23.6219880383
60PhosphorylationSSLSRSIYSDRFIPS
CHHHHHHHCCCCCCC
13.0319880383

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of FZR2_ARATH !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of FZR2_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of FZR2_ARATH !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
APC4_SCHPOcut20physical
15970679
CDKA1_ARATHCDC2physical
15970679
CDC23_ARATHAPC8physical
20706207
APC1_ARATHEMB2771physical
20706207
APC4_ARATHAT4G21530physical
20706207
APC5_ARATHAT1G06590physical
20706207
IF2B_ARATHEIF2 BETAphysical
20706207
TCPA_ARATHTCP-1physical
20706207
APC2_ARATHAPC2physical
20706207
APC7_ARATHAT2G39090physical
20706207
CD27B_ARATHHBTphysical
20706207
PSMD6_ARATHAT4G24820physical
20706207
EF115_ARATHAT5G07310physical
20706207
COB22_ARATHAT1G52360physical
20706207
EIF3C_ARATHEIF3Cphysical
20706207
THO4B_ARATHAT5G02530physical
20706207
C3H24_ARATHAT2G28450physical
20706207

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of FZR2_ARATH

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Related Literatures of Post-Translational Modification

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