| UniProt ID | ETR2_ARATH | |
|---|---|---|
| UniProt AC | Q0WPQ2 | |
| Protein Name | Ethylene receptor 2 | |
| Gene Name | ETR2 | |
| Organism | Arabidopsis thaliana (Mouse-ear cress). | |
| Sequence Length | 773 | |
| Subcellular Localization |
Endoplasmic reticulum membrane Multi-pass membrane protein . |
|
| Protein Description | Ethylene receptor related to bacterial two-component regulators. Acts as a redundant negative regulator of ethylene signaling.. | |
| Protein Sequence | MVKEIASWLLILSMVVFVSPVLAINGGGYPRCNCEDEGNSFWSTENILETQRVSDFLIAVAYFSIPIELLYFVSCSNVPFKWVLFEFIAFIVLCGMTHLLHGWTYSAHPFRLMMAFTVFKMLTALVSCATAITLITLIPLLLKVKVREFMLKKKAHELGREVGLILIKKETGFHVRMLTQEIRKSLDRHTILYTTLVELSKTLGLQNCAVWMPNDGGTEMDLTHELRGRGGYGGCSVSMEDLDVVRIRESDEVNVLSVDSSIARASGGGGDVSEIGAVAAIRMPMLRVSDFNGELSYAILVCVLPGGTPRDWTYQEIEIVKVVADQVTVALDHAAVLEESQLMREKLAEQNRALQMAKRDALRASQARNAFQKTMSEGMRRPMHSILGLLSMIQDEKLSDEQKMIVDTMVKTGNVMSNLVGDSMDVPDGRFGTEMKPFSLHRTIHEAACMARCLCLCNGIRFLVDAEKSLPDNVVGDERRVFQVILHIVGSLVKPRKRQEGSSLMFKVLKERGSLDRSDHRWAAWRSPASSADGDVYIRFEMNVENDDSSSQSFASVSSRDQEVGDVRFSGGYGLGQDLSFGVCKKVVQLIHGNISVVPGSDGSPETMSLLLRFRRRPSISVHGSSESPAPDHHAHPHSNSLLRGLQVLLVDTNDSNRAVTRKLLEKLGCDVTAVSSGFDCLTAIAPGSSSPSTSFQVVVLDLQMAEMDGYEVAMRIRSRSWPLIVATTVSLDEEMWDKCAQIGINGVVRKPVVLRAMESELRRVLLQADQLL | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 507 | Acetylation | EGSSLMFKVLKERGS CCCCHHHHHHHHCCC | 32.46 | 21311031 | |
| 527 | Phosphorylation | HRWAAWRSPASSADG CCEEECCCCCCCCCC | 17.70 | 29654922 | |
| 530 | Phosphorylation | AAWRSPASSADGDVY EECCCCCCCCCCCEE | 29.46 | 29654922 | |
| 531 | Phosphorylation | AWRSPASSADGDVYI ECCCCCCCCCCCEEE | 32.27 | 19880383 | |
| 702 | Phosphorylation | SFQVVVLDLQMAEMD CEEEEEEEEEECCCC | 24.20 | - | |
| 751 | Ubiquitination | GINGVVRKPVVLRAM CCCCEECCHHHHHHH | 30.47 | 17272265 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of ETR2_ARATH !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of ETR2_ARATH !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of ETR2_ARATH !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| ETR1_ARATH | ETR1 | physical | 18577522 | |
| UBC34_ARATH | UBC34 | physical | 24833385 | |
| CNIH1_ARATH | AT3G12180 | physical | 24833385 | |
| YSL8_ARATH | YSL8 | physical | 24833385 | |
| TBL36_ARATH | TBL36 | physical | 24833385 | |
| IF5A2_ARATH | FBR12 | physical | 26207341 | |
| PSA7B_ARATH | PAD2 | physical | 26207341 | |
| ADF3_ARATH | ADF3 | physical | 26207341 | |
| MD37F_ARATH | BIP2 | physical | 26207341 | |
| Y5520_ARATH | AT5G05200 | physical | 26207341 | |
| NACA4_ARATH | AT4G10480 | physical | 26207341 | |
| WAKLM_ARATH | AT4G31100 | physical | 26207341 | |
| HSP7G_ARATH | CPHSC70-2EAT SHOCK PROTEIN 70-2 | physical | 26207341 | |
| EIN4_ARATH | EIN4 | physical | 26207341 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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| Ubiquitylation | |
| Reference | PubMed |
| "Multidimensional protein identification technology (MudPIT) analysisof ubiquitinated proteins in plants."; Maor R., Jones A., Nuehse T.S., Studholme D.J., Peck S.C., Shirasu K.; Mol. Cell. Proteomics 6:601-610(2007). Cited for: UBIQUITINATION [LARGE SCALE ANALYSIS] AT LYS-751, AND MASSSPECTROMETRY. | |
