YSL8_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: YSL8_ARATH
• UniProt AC: Q6R3K4
• Protein Name: Probable metal-nicotianamine transporter YSL8
• Gene Name: YSL8
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 724
• Subcellular Localization: Membrane ; Multi-pass membrane protein .
• Protein Description: May be involved in the transport of nicotianamine-chelated metals..
• Protein Sequence: MRKGGLTPDRDRQIEEHELQETGISPDIERLKRNINATPYQREEEEEDREEQEESVEGIFESREVPSWKKQLTIRAFVVSFALSILFSFIVMKLNLTTGIIPSLNVSAGLLGFFFVKTWTKMLHKSGLLKQPFTRQENTVIQTCVVASSGIAFSGGFGTYLFAMSHRIADQSGDVARGVKDPSLGWMIAFLFVVSFLGLFSVVPLRKIMIIDFKLPYPSGTATAHLINSFHTPQGAKLAKKQVRVLGKFFSFSFFWGFFQWFFTAGENCGFNSFPTFGLRAYQYKFYFDFSATYVGVGMICPYIINISLLLGGILSWGLMWPLIETRKGDWFPSNVDSSSMNGLQAYKVFIAVATILGDGLYNFCKVLIRTFSGLISQIRGKAGSRSSLAHKEDPPASPASPLTPRISYDDQRRTRFFLKDQIPSWFAVGGYVVISAVSTAILPHMFSQLRWYYIIVIYIFAPILAFCNAYGAGLTDWSLASTYGKLAIFTIGAWAGSDHGGLLAGLAACGVMMNIVSTASDLTQDFKTGYLTLSSPRAMFVSQVIGTAMGCLVSPCVFWLFYKAFDDLGLPNSEYPAPFATVYRSMAKLGVEGVSSLPRDCLMLCYVFFGVAILINLIKDCLGNRWGRFVPLPMAMAIPFFLGPYFAIDMCVGSFILFVWERLDAPKAEAFATAVASGLICGDGIWTLPSSVLAIAGVKPPICMKFLSAATNHRVDKFLQGSS

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
7	Phosphorylation	-MRKGGLTPDRDRQI -CCCCCCCCCHHHHH	26.81	17317660
22	Phosphorylation	EEHELQETGISPDIE HHHHHHHHCCCCCHH	27.19	30407730
25	Phosphorylation	ELQETGISPDIERLK HHHHHCCCCCHHHHH	20.19	30291188
55	Phosphorylation	DREEQEESVEGIFES HHHHHHHHHHHHHHC	25.39	23110452
398	Phosphorylation	HKEDPPASPASPLTP CCCCCCCCCCCCCCC	27.11	17317660
401	Phosphorylation	DPPASPASPLTPRIS CCCCCCCCCCCCCCC	24.67	30291188
404	Phosphorylation	ASPASPLTPRISYDD CCCCCCCCCCCCCCC	17.57	17317660

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of YSL8_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of YSL8_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of YSL8_ARATH !!

Protein-Protein Interaction

Oops, there are no PPI records of YSL8_ARATH !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Phosphorylation

"Novel subsets of the Arabidopsis plasmalemma phosphoproteome identifyphosphorylation sites in secondary active transporters.";
Hem S., Rofidal V., Sommerer N., Rossignol M.;
Biochem. Biophys. Res. Commun. 363:375-380(2007).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-25, AND MASSSPECTROMETRY.
PubMed: 17869214