ESMB_DROME - dbPTM
ESMB_DROME - PTM Information in dbPTM
Basic Information of Protein
UniProt ID ESMB_DROME
UniProt AC Q01069
Protein Name Enhancer of split mbeta protein
Gene Name E(spl)mbeta-HLH {ECO:0000312|FlyBase:FBgn0002733}
Organism Drosophila melanogaster (Fruit fly).
Sequence Length 195
Subcellular Localization Nucleus .
Protein Description Transcriptional repressor of genes that require a bHLH protein for their transcription (By similarity). May serve as a transcriptional regulator of the Achaete-scute complex (AS-C) genes. [PubMed: 1528887 Contributes to the neural-epidermal lineage decision during early neurogenesis]
Protein Sequence MVLEMEMSKTYQYRKVMKPMLERKRRARINKCLDELKDIMVECLTQEGEHITRLEKADILELTVEHMKKLRAQKQLRLSSVTGGVSPSADPKLSIAESFRAGYVHAANEVSKTLAAVPGVSVDLGTQLMSHLGHRLNYLQVVVPSLPIGVPLQAPVEDQAMVTPPPSECDSLESGACSPAPSEASSTSGPMWRPW
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster

Oops, there are no PTM records of ESMB_DROME !!

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of ESMB_DROME !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of ESMB_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of ESMB_DROME !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
EGON_DROMEegphysical
14605208
TAP_DROMEtapphysical
14605208
SUDX_DROMESu(dx)genetic
9832525
EMC_DROMEemcgenetic
10804180
AST5_DROMEacphysical
9371806
AST4_DROMEscphysical
9371806
AST4_DROMEscphysical
9524128
AST8_DROMEasephysical
9371806
DA_DROMEdaphysical
9371806
ATO_DROMEatophysical
9371806
ESMD_DROMEE(spl)mdelta-HLHphysical
9371806
ESMC_DROMEE(spl)mgamma-HLHphysical
9371806
ESMB_DROMEE(spl)mbeta-HLHphysical
9371806
ESM5_DROMEE(spl)m5-HLHphysical
9371806
ESM8_DROMEE(spl)m8-HLHphysical
9371806
GROU_DROMEgrophysical
16762837
GROU_DROMEgrophysical
9371806
GROU_DROMEgrophysical
9524128

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of ESMB_DROME

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Related Literatures of Post-Translational Modification

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