ESM5_DROME - dbPTM
ESM5_DROME - PTM Information in dbPTM
Basic Information of Protein
UniProt ID ESM5_DROME
UniProt AC P13096
Protein Name Enhancer of split m5 protein
Gene Name E(spl)m5-HLH {ECO:0000312|FlyBase:FBgn0002631}
Organism Drosophila melanogaster (Fruit fly).
Sequence Length 178
Subcellular Localization Nucleus .
Protein Description Participates in the control of cell fate choice by uncommitted neuroectodermal cells in the embryo. Transcriptional repressor. Binds DNA on N-box motifs: 5'-CACNAG-3'..
Protein Sequence MAPQSNNSTTFVSKTQHYLKVKKPLLERQRRARMNKCLDTLKTLVAEFQGDDAILRMDKAEMLEAALVFMRKQVVKQQAPVSPLPMDSFKNGYMNAVSEISRVMACTPAMSVDVGKTVMTHLGVEFQRMLQADQVQTSVTTSTPRPLSPASSGYHSDNEDSQSAASPKPVEETMWRPW
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster

Oops, there are no PTM records of ESM5_DROME !!

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of ESM5_DROME !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of ESM5_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of ESM5_DROME !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
EGON_DROMEegphysical
14605208
TAP_DROMEtapphysical
14605208
GROU_DROMEgrophysical
14605208
DA_DROMEdaphysical
9371806
ESMD_DROMEE(spl)mdelta-HLHphysical
9371806
ESMC_DROMEE(spl)mgamma-HLHphysical
9371806
ESMB_DROMEE(spl)mbeta-HLHphysical
9371806
ESM5_DROMEE(spl)m5-HLHphysical
9371806
ESM8_DROMEE(spl)m8-HLHphysical
9371806
GROU_DROMEgrophysical
16762837
GROU_DROMEgrophysical
8001118
GROU_DROMEgrophysical
9371806
GROU_DROMEgrophysical
9524128

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of ESM5_DROME

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Related Literatures of Post-Translational Modification

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