CUT7_SCHPO - dbPTM
CUT7_SCHPO - PTM Information in dbPTM
Basic Information of Protein
UniProt ID CUT7_SCHPO
UniProt AC P24339
Protein Name Kinesin-like protein cut7
Gene Name cut7
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length 1085
Subcellular Localization Cytoplasm, cytoskeleton, microtubule organizing center, spindle pole body.
Protein Description Could be a spindle pole body motor. On transition from G2 to M phase of the cell cycle, the spindle pole body duplicates; the daughter pole bodies seed microtubules which interdigitate to form a short spindle that elongates to span the nucleus at metaphase. Mutations at cut7 block spindle formation..
Protein Sequence MAPRVAPGGSQQFLGKQGLKAKNPVSTPNSHFRSASNPRKRREPPTIDTGYPDRSDTNSPTDHALHDENETNINVVVRVRGRTDQEVRDNSSLAVSTSGAMGAELAIQSDPSSMLVTKTYAFDKVFGPEADQLMLFENSVAPMLEQVLNGYNCTIFAYGQTGTGKTYTMSGDLSDSDGILSEGAGLIPRALYQLFSSLDNSNQEYAVKCSYYELYNEEIRDLLVSEELRKPARVFEDTSRRGNVVITGIEESYIKNAGDGLRLLREGSHRRQVAATKCNDLSSRSHSIFTITLHRKVSSGMTDETNSLTINNNSDDLLRASKLHMVDLAGSENIGRSGAENKRARETGMINQSLLTLGRVINALVEKAHHIPYRESKLTRLLQDSLGGKTKTSMIVTVSSTNTNLEETISTLEYAARAKSIRNKPQNNQLVFRKVLIKDLVLDIERLKNDLNATRKKNGVYLAESTYKELMDRVQNKDLLCQEQARKLEVLDLNVKSSREQLQYVSKSNQEHKKEVEALQLQLVNSSTELESVKSENEKLKNELVLEIEKRKKYETNEAKITTVATDLSQYYRESKEYIASLYEKLDRTERNNKENENNFWNLKFNLLTMLRSFHGSFTDETNGYFTLLNDFNASMEELLNTHSNQLLISMTKITEHFQSLDEALQSARSSCAVPNSSLDLIVSELKDSKNSLLDALEHSLQDISMSSQKLGNGISSELIELQKDMKESYRQLVQELRSLYNLQHTHEESQKELMYGVRNDIDALVKTCTTSLNDADIILSDYISDQKSKFESKQQDLIANIGKIVSNFLQEQNESLYTKADILHSHLNDTNSNIRKANEIMNNRSEEFLRNAASQAEIVGANKERIQKTVENGSQLLDSKSKAIHSNSRSMYDHCLALAESQKQGVNLEVQTLDRLLQKVKEHSEDNTKEKHQQLLDLLESLVGNNDNLIDSIKTPHTELQKITDHVLKGTTSLANHTNELLGLGDESLCNLETTIEDTSLVKLETTGDTPSKRELPATPSWTRDSSLIKETTNLNLDSDKKFVRETYTSSNQTNEPDVYDKPSNSSRTSLLRSSRSAYSKMKR
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
771PhosphorylationALVKTCTTSLNDADI
HHHHHHCCCCCHHHH
33.1027738172
1007PhosphorylationTSLVKLETTGDTPSK
CCEEEEEECCCCCCC
46.6529996109
1008PhosphorylationSLVKLETTGDTPSKR
CEEEEEECCCCCCCC
24.5529996109
1011PhosphorylationKLETTGDTPSKRELP
EEEECCCCCCCCCCC
30.7021712547
1013PhosphorylationETTGDTPSKRELPAT
EECCCCCCCCCCCCC
46.5729996109
1020PhosphorylationSKRELPATPSWTRDS
CCCCCCCCCCCCCCC
18.8621712547
1024PhosphorylationLPATPSWTRDSSLIK
CCCCCCCCCCCHHCH
29.0121712547
1027PhosphorylationTPSWTRDSSLIKETT
CCCCCCCCHHCHHHC
24.6121712547
1028PhosphorylationPSWTRDSSLIKETTN
CCCCCCCHHCHHHCC
38.1021712547

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources
1011TPhosphorylationKinaseCDC2P04551
Uniprot

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of CUT7_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of CUT7_SCHPO !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
KLP2_SCHPOklp2genetic
11694582
KLP1_SCHPOpkl1genetic
11694582
KLP1_SCHPOpkl1genetic
8898367
KLP1_SCHPOpkl1genetic
18418055
TBG_SCHPOgtb1genetic
18418055
ALP4_SCHPOalp4genetic
18418055
ALP6_SCHPOalp6genetic
18418055
AGO1_SCHPOago1physical
19883398
DCR1_SCHPOdcr1physical
19883398
RDP1_SCHPOrdp1physical
19883398
ASK1_SCHPOask1genetic
18818364
ALP14_SCHPOalp14genetic
18818364
MPH1L_SCHPOmph1genetic
22681890
CYB51_SCHPOSPBC29A10.16cgenetic
22681890
ASK1_SCHPOask1genetic
22681890
DAD2_SCHPOdad2genetic
22681890
YCV2_SCHPOSPCC777.02genetic
22681890
KLP1_SCHPOpkl1genetic
23388459
VIP1_SCHPOasp1genetic
27697865
KLP1_SCHPOpkl1genetic
25348260
KLP1_SCHPOpkl1physical
25348260
TBG_SCHPOgtb1physical
25348260
ALP4_SCHPOalp4physical
25348260

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of CUT7_SCHPO

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Related Literatures of Post-Translational Modification

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