UniProt ID | CUT7_SCHPO | |
---|---|---|
UniProt AC | P24339 | |
Protein Name | Kinesin-like protein cut7 | |
Gene Name | cut7 | |
Organism | Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast). | |
Sequence Length | 1085 | |
Subcellular Localization | Cytoplasm, cytoskeleton, microtubule organizing center, spindle pole body. | |
Protein Description | Could be a spindle pole body motor. On transition from G2 to M phase of the cell cycle, the spindle pole body duplicates; the daughter pole bodies seed microtubules which interdigitate to form a short spindle that elongates to span the nucleus at metaphase. Mutations at cut7 block spindle formation.. | |
Protein Sequence | MAPRVAPGGSQQFLGKQGLKAKNPVSTPNSHFRSASNPRKRREPPTIDTGYPDRSDTNSPTDHALHDENETNINVVVRVRGRTDQEVRDNSSLAVSTSGAMGAELAIQSDPSSMLVTKTYAFDKVFGPEADQLMLFENSVAPMLEQVLNGYNCTIFAYGQTGTGKTYTMSGDLSDSDGILSEGAGLIPRALYQLFSSLDNSNQEYAVKCSYYELYNEEIRDLLVSEELRKPARVFEDTSRRGNVVITGIEESYIKNAGDGLRLLREGSHRRQVAATKCNDLSSRSHSIFTITLHRKVSSGMTDETNSLTINNNSDDLLRASKLHMVDLAGSENIGRSGAENKRARETGMINQSLLTLGRVINALVEKAHHIPYRESKLTRLLQDSLGGKTKTSMIVTVSSTNTNLEETISTLEYAARAKSIRNKPQNNQLVFRKVLIKDLVLDIERLKNDLNATRKKNGVYLAESTYKELMDRVQNKDLLCQEQARKLEVLDLNVKSSREQLQYVSKSNQEHKKEVEALQLQLVNSSTELESVKSENEKLKNELVLEIEKRKKYETNEAKITTVATDLSQYYRESKEYIASLYEKLDRTERNNKENENNFWNLKFNLLTMLRSFHGSFTDETNGYFTLLNDFNASMEELLNTHSNQLLISMTKITEHFQSLDEALQSARSSCAVPNSSLDLIVSELKDSKNSLLDALEHSLQDISMSSQKLGNGISSELIELQKDMKESYRQLVQELRSLYNLQHTHEESQKELMYGVRNDIDALVKTCTTSLNDADIILSDYISDQKSKFESKQQDLIANIGKIVSNFLQEQNESLYTKADILHSHLNDTNSNIRKANEIMNNRSEEFLRNAASQAEIVGANKERIQKTVENGSQLLDSKSKAIHSNSRSMYDHCLALAESQKQGVNLEVQTLDRLLQKVKEHSEDNTKEKHQQLLDLLESLVGNNDNLIDSIKTPHTELQKITDHVLKGTTSLANHTNELLGLGDESLCNLETTIEDTSLVKLETTGDTPSKRELPATPSWTRDSSLIKETTNLNLDSDKKFVRETYTSSNQTNEPDVYDKPSNSSRTSLLRSSRSAYSKMKR | |
Overview of Protein Modification Sites with Functional and Structural Information | ||
* ASA = Accessible Surface Area
Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
---|---|---|---|---|---|
771 | Phosphorylation | ALVKTCTTSLNDADI HHHHHHCCCCCHHHH | 33.10 | 27738172 | |
1007 | Phosphorylation | TSLVKLETTGDTPSK CCEEEEEECCCCCCC | 46.65 | 29996109 | |
1008 | Phosphorylation | SLVKLETTGDTPSKR CEEEEEECCCCCCCC | 24.55 | 29996109 | |
1011 | Phosphorylation | KLETTGDTPSKRELP EEEECCCCCCCCCCC | 30.70 | 21712547 | |
1013 | Phosphorylation | ETTGDTPSKRELPAT EECCCCCCCCCCCCC | 46.57 | 29996109 | |
1020 | Phosphorylation | SKRELPATPSWTRDS CCCCCCCCCCCCCCC | 18.86 | 21712547 | |
1024 | Phosphorylation | LPATPSWTRDSSLIK CCCCCCCCCCCHHCH | 29.01 | 21712547 | |
1027 | Phosphorylation | TPSWTRDSSLIKETT CCCCCCCCHHCHHHC | 24.61 | 21712547 | |
1028 | Phosphorylation | PSWTRDSSLIKETTN CCCCCCCHHCHHHCC | 38.10 | 21712547 |
Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
---|---|---|---|---|---|---|
1011 | T | Phosphorylation | Kinase | CDC2 | P04551 | Uniprot |
Modified Location | Modified Residue | Modification | Function | Reference | ||
---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of CUT7_SCHPO !! |
* Distance = the distance between SAP position and PTM sites.
Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of CUT7_SCHPO !! |
Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
---|---|---|---|---|
KLP2_SCHPO | klp2 | genetic | 11694582 | |
KLP1_SCHPO | pkl1 | genetic | 11694582 | |
KLP1_SCHPO | pkl1 | genetic | 8898367 | |
KLP1_SCHPO | pkl1 | genetic | 18418055 | |
TBG_SCHPO | gtb1 | genetic | 18418055 | |
ALP4_SCHPO | alp4 | genetic | 18418055 | |
ALP6_SCHPO | alp6 | genetic | 18418055 | |
AGO1_SCHPO | ago1 | physical | 19883398 | |
DCR1_SCHPO | dcr1 | physical | 19883398 | |
RDP1_SCHPO | rdp1 | physical | 19883398 | |
ASK1_SCHPO | ask1 | genetic | 18818364 | |
ALP14_SCHPO | alp14 | genetic | 18818364 | |
MPH1L_SCHPO | mph1 | genetic | 22681890 | |
CYB51_SCHPO | SPBC29A10.16c | genetic | 22681890 | |
ASK1_SCHPO | ask1 | genetic | 22681890 | |
DAD2_SCHPO | dad2 | genetic | 22681890 | |
YCV2_SCHPO | SPCC777.02 | genetic | 22681890 | |
KLP1_SCHPO | pkl1 | genetic | 23388459 | |
VIP1_SCHPO | asp1 | genetic | 27697865 | |
KLP1_SCHPO | pkl1 | genetic | 25348260 | |
KLP1_SCHPO | pkl1 | physical | 25348260 | |
TBG_SCHPO | gtb1 | physical | 25348260 | |
ALP4_SCHPO | alp4 | physical | 25348260 |
Kegg Drug | ||||||
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DrugBank | ||||||
There are no disease associations of PTM sites. |
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