| UniProt ID | CORTO_DROME | |
|---|---|---|
| UniProt AC | P41046 | |
| Protein Name | Centrosomal and chromosomal factor | |
| Gene Name | corto | |
| Organism | Drosophila melanogaster (Fruit fly). | |
| Sequence Length | 550 | |
| Subcellular Localization | Nucleus . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Chromosome . | |
| Protein Description | Essential protein required for proper condensation of mitotic chromosomes and progression through mitosis. [PubMed: 9463384 Binds to specific polytene chromosome sites, many of which are shared with the posterior sex combs (Psc) protein] | |
| Protein Sequence | MTMAACYANYDMSSLSHGMSALSALQQQQQQQQQQHSQTQQQHHHQQQQQHMYHAAVAAHQQQLLQQQQQQQHHRHHHQPANTSSSSNSRHSHAAATQTQVAAAVANSRQQQQQQQQQQQQQQQQQTASSNSNAAPAPSPQKDYSIPLHVDCSVEYELPNQPKPPAGQRVEPLLMIHPCYFRKMESQRRSPFVNNMHATARAVSSSSLSSGAALGGGGSGAAVATAPSSSAARRGARAATSAQQQQQQQQRYQQQQQQLRQQHQQMSQMSQQAHYPQQQSSLVRQHQQQQQQQQQQQRASSNQSQRQSQSQSQSQSHAANSAAAAAAQASIAAAAAGQWDQLAALAARTALTPHHMLHPHSHYAAKGSGGGAGGGKRDAMISGSYGQTAVASGKLQQSQVQQQQPQQQQQHCLPPPPWDATSMLMDRSPMATVPSNYQAGPDTNPMRLYSATPTAGAASGGSASVGGGGAVSGAGATGAVNTATDKLSGKYRQYLRSQRMHPYAAAASLNLAAAAAAAGQTSFVPFSSAATAVAATPTFQHLPQISCYNV | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 190 | Phosphorylation | KMESQRRSPFVNNMH HCHHHCCCCCCCCHH | 25.53 | 22817900 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of CORTO_DROME !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of CORTO_DROME !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of CORTO_DROME !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| EZ_DROME | E(z) | genetic | 9463384 | |
| OSA_DROME | osa | genetic | 11810228 | |
| ELOA1_DROME | EloA | genetic | 24204884 | |
| GAGA_DROME | Trl | genetic | 11810228 | |
| GAGA_DROME | Trl | physical | 12771214 | |
| PHP_DROME | ph-p | physical | 12771214 | |
| ERKA_DROME | rl | physical | 21401930 | |
| PIWI_DROME | piwi | physical | 26780607 | |
| ESC_DROME | esc | physical | 12771214 | |
| LTOR3_DROME | CG5110 | physical | 21401930 | |
| EZ_DROME | E(z) | physical | 12771214 | |
| EZ_DROME | E(z) | physical | 26780607 | |
| CORTO_DROME | corto | physical | 12771214 | |
| SCM_DROME | Scm | physical | 12771214 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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