COL10_HUMAN - dbPTM
COL10_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID COL10_HUMAN
UniProt AC Q9Y6Z7
Protein Name Collectin-10
Gene Name COLEC10
Organism Homo sapiens (Human).
Sequence Length 277
Subcellular Localization Secreted . Golgi apparatus . Cytoplasm .
Protein Description Lectin that binds to various sugars: galactose > mannose = fucose > N-acetylglucosamine > N-acetylgalactosamine. [PubMed: 10224141 Acts as a chemoattractant, probably involved in the regulation of cell migration]
Protein Sequence MNGFASLLRRNQFILLVLFLLQIQSLGLDIDSRPTAEVCATHTISPGPKGDDGEKGDPGEEGKHGKVGRMGPKGIKGELGDMGDQGNIGKTGPIGKKGDKGEKGLLGIPGEKGKAGTVCDCGRYRKFVGQLDISIARLKTSMKFVKNVIAGIRETEEKFYYIVQEEKNYRESLTHCRIRGGMLAMPKDEAANTLIADYVAKSGFFRVFIGVNDLEREGQYMFTDNTPLQNYSNWNEGEPSDPYGHEDCVEMLSSGRWNDTECHLTMYFVCEFIKKKK
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
35O-linked_GlycosylationLDIDSRPTAEVCATH
CCCCCCCCCEEEEEE		34.05OGP
66AcetylationGEEGKHGKVGRMGPK
CCCCCCCCCCCCCCC		41.0310523039
73AcetylationKVGRMGPKGIKGELG
CCCCCCCCCCCCCCC		68.4910523035
90AcetylationGDQGNIGKTGPIGKK
CCCCCCCCCCCCCCC		46.6511194815
96AcetylationGKTGPIGKKGDKGEK
CCCCCCCCCCCCCCC		55.0611194825
97AcetylationKTGPIGKKGDKGEKG
CCCCCCCCCCCCCCC		68.1011194835
100AcetylationPIGKKGDKGEKGLLG
CCCCCCCCCCCCCCC		77.09164413
103AcetylationKKGDKGEKGLLGIPG
CCCCCCCCCCCCCCC		64.62164417
141PhosphorylationSIARLKTSMKFVKNV
CHHHHHHHHHHHHHH		20.56-
155PhosphorylationVIAGIRETEEKFYYI
HHHHHHHCHHHHEEE		39.33-
201AcetylationLIADYVAKSGFFRVF
HHHHHHHHHCCEEEE		40.8619825937
258N-linked_GlycosylationMLSSGRWNDTECHLT
HHHCCCCCCCCHHHH		44.99UniProtKB CARBOHYD
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of COL10_HUMAN !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of COL10_HUMAN !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of COL10_HUMAN !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
NUCB2_HUMANNUCB2physical
26186194
SC65_HUMANP3H4physical
26186194
GT252_HUMANCOLGALT2physical
26186194
DNJB9_HUMANDNAJB9physical
26186194
CKAP4_HUMANCKAP4physical
26186194
TGO1_HUMANMIA3physical
26186194
ARL8A_HUMANARL8Aphysical
26186194
TIMP3_HUMANTIMP3physical
26186194
PTX3_HUMANPTX3physical
26186194
STC2_HUMANSTC2physical
26186194
INHBE_HUMANINHBEphysical
26186194
MCU_HUMANMCUphysical
26186194
DCP2_HUMANDCP2physical
26186194
PTX3_HUMANPTX3physical
28514442
INHBE_HUMANINHBEphysical
28514442
DCP2_HUMANDCP2physical
28514442
NUCB2_HUMANNUCB2physical
28514442
TIMP3_HUMANTIMP3physical
28514442
CKAP4_HUMANCKAP4physical
28514442
SC65_HUMANP3H4physical
28514442
DNJB9_HUMANDNAJB9physical
28514442
GT252_HUMANCOLGALT2physical
28514442
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of COL10_HUMAN

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Related Literatures of Post-Translational Modification

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