| UniProt ID | TGO1_HUMAN | |
|---|---|---|
| UniProt AC | Q5JRA6 | |
| Protein Name | Transport and Golgi organization protein 1 homolog {ECO:0000305} | |
| Gene Name | MIA3 {ECO:0000312|HGNC:HGNC:24008} | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 1907 | |
| Subcellular Localization |
Endoplasmic reticulum membrane Single-pass membrane protein . Localizes at endoplasmic reticulum exit sites. After loading of COL7A1 into transport carriers, it is not incorporated into COPII carriers and remains in the endoplasmic reticulum membra |
|
| Protein Description | Plays a role in the transport of cargos that are too large to fit into COPII-coated vesicles and require specific mechanisms to be incorporated into membrane-bound carriers and exported from the endoplasmic reticulum. This protein is required for collagen VII (COL7A1) secretion by loading COL7A1 into transport carriers. It may participate in cargo loading of COL7A1 at endoplasmic reticulum exit sites by binding to COPII coat subunits Sec23/24 and guiding SH3-bound COL7A1 into a growing carrier. Does not play a role in global protein secretion and is apparently specific to COL7A1 cargo loading. However, it may participate in secretion of other proteins in cells that do not secrete COL7A1. It is also specifically required for the secretion of lipoproteins by participating in their export from the endoplasmic reticulum. [PubMed: 27138255] | |
| Protein Sequence | MAAAPGLLVWLLVLRLPWRVPGQLDPSTGRRFSEHKLCADDECSMLMYRGEALEDFTGPDCRFVNFKKGDPVYVYYKLARGWPEVWAGSVGRTFGYFPKDLIQVVHEYTKEELQVPTDETDFVCFDGGRDDFHNYNVEELLGFLELYNSAATDSEKAVEKTLQDMEKNPELSKEREPEPEPVEANSEESDSVFSENTEDLQEQFTTQKHHSHANSQANHAQGEQASFESFEEMLQDKLKVPESENNKTSNSSQVSNEQDKIDAYKLLKKEMTLDLKTKFGSTADALVSDDETTRLVTSLEDDFDEELDTEYYAVGKEDEENQEDFDELPLLTFTDGEDMKTPAKSGVEKYPTDKEQNSNEEDKVQLTVPPGIKNDDKNILTTWGDTIFSIVTGGEETRDTMDLESSSSEEEKEDDDDALVPDSKQGKPQSATDYSDPDNVDDGLFIVDIPKTNNDKEVNAEHHIKGKGRGVQESKRGLVQDKTELEDENQEGMTVHSSVHSNNLNSMPAAEKGKDTLKSAYDDTENDLKGAAIHISKGMLHEEKPGEQILEGGSESESAQKAAGNQMNDRKIQQESLGSAPLMGDDHPNASRDSVEGDALVNGAKLHTLSVEHQREELKEELVLKTQNQPRFSSPDEIDLPRELEDEVPILGRNLPWQQERDVAATASKQMSEKIRLSEGEAKEDSLDEEFFHHKAMQGTEVGQTDQTDSTGGPAFLSKVEEDDYPSEELLEDENAINAKRSKEKNPGNQGRQFDVNLQVPDRAVLGTIHPDPEIEESKQETSMILDSEKTSETAAKGVNTGGREPNTMVEKERPLADKKAQRPFERSDFSDSIKIQTPELGEVFQNKDSDYLKNDNPEEHLKTSGLAGEPEGELSKEDHENTEKYMGTESQGSAAAEPEDDSFHWTPHTSVEPGHSDKREDLLIISSFFKEQQSLQRFQKYFNVHELEALLQEMSSKLKSAQQESLPYNMEKVLDKVFRASESQILSIAEKMLDTRVAENRDLGMNENNIFEEAAVLDDIQDLIYFVRYKHSTAEETATLVMAPPLEEGLGGAMEEMQPLHEDNFSREKTAELNVQVPEEPTHLDQRVIGDTHASEVSQKPNTEKDLDPGPVTTEDTPMDAIDANKQPETAAEEPASVTPLENAILLIYSFMFYLTKSLVATLPDDVQPGPDFYGLPWKPVFITAFLGIASFAIFLWRTVLVVKDRVYQVTEQQISEKLKTIMKENTELVQKLSNYEQKIKESKKHVQETRKQNMILSDEAIKYKDKIKTLEKNQEILDDTAKNLRVMLESEREQNVKNQDLISENKKSIEKLKDVISMNASEFSEVQIALNEAKLSEEKVKSECHRVQEENARLKKKKEQLQQEIEDWSKLHAELSEQIKSFEKSQKDLEVALTHKDDNINALTNCITQLNLLECESESEGQNKGGNDSDELANGEVGGDRNEKMKNQIKQMMDVSRTQTAISVVEEDLKLLQLKLRASVSTKCNLEDQVKKLEDDRNSLQAAKAGLEDECKTLRQKVEILNELYQQKEMALQKKLSQEEYERQEREHRLSAADEKAVSAAEEVKTYKRRIEEMEDELQKTERSFKNQIATHEKKAHENWLKARAAERAIAEEKREAANLRHKLLELTQKMAMLQEEPVIVKPMPGKPNTQNPPRRGPLSQNGSFGPSPVSGGECSPPLTVEPPVRPLSATLNRRDMPRSEFGSVDGPLPHPRWSAEASGKPSPSDPGSGTATMMNSSSRGSSPTRVLDEGKVNMAPKGPPPFPGVPLMSTPMGGPVPPPIRYGPPPQLCGPFGPRPLPPPFGPGMRPPLGLREFAPGVPPGRRDLPLHPRGFLPGHAPFRPLGSLGPREYFIPGTRLPPPTHGPQEYPPPPAVRDLLPSGSRDEPPPASQSTSQDCSQALKQSP | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
|
|
||
* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 33 | Phosphorylation | PSTGRRFSEHKLCAD CCCCCCCCCCCCCCC | - | ||
| 44 | Phosphorylation | LCADDECSMLMYRGE CCCCCCCCEEEECCC | - | ||
| 57 | Phosphorylation | GEALEDFTGPDCRFV CCCCHHCCCCCCEEE | - | ||
| 67 | Ubiquitination | DCRFVNFKKGDPVYV CCEEECCCCCCCEEE | 27667366 | ||
| 73 | Phosphorylation | FKKGDPVYVYYKLAR CCCCCCEEEEEEECC | - | ||
| 97 | Ubiquitination | VGRTFGYFPKDLIQV CCCCCCCCCHHHHHH | 33845483 | ||
| 111 | Ubiquitination | VVHEYTKEELQVPTD HHHHHCHHHHCCCCC | 29967540 | ||
| 114 | Ubiquitination | EYTKEELQVPTDETD HHCHHHHCCCCCCCC | 29967540 | ||
| 118 | Ubiquitination | EELQVPTDETDFVCF HHHCCCCCCCCEEEE | 29901268 | ||
| 131 | Ubiquitination | CFDGGRDDFHNYNVE EEECCCCCCCCCCHH | 29967540 | ||
| 149 | Phosphorylation | GFLELYNSAATDSEK HHHHHHHHCCCCHHH | 26657352 | ||
| 150 | Ubiquitination | FLELYNSAATDSEKA HHHHHHHCCCCHHHH | 27667366 | ||
| 152 | Ubiquitination | ELYNSAATDSEKAVE HHHHHCCCCHHHHHH | 29967540 | ||
| 156 | Ubiquitination | SAATDSEKAVEKTLQ HCCCCHHHHHHHHHH | 29967540 | ||
| 161 | O-linked_Glycosylation | SEKAVEKTLQDMEKN HHHHHHHHHHHHHHC | 55832339 | ||
| 162 | Ubiquitination | EKAVEKTLQDMEKNP HHHHHHHHHHHHHCH | 29967540 | ||
| 186 | Phosphorylation | PEPVEANSEESDSVF CCCCCCCCHHCCCCC | 28192239 | ||
| 189 | Phosphorylation | VEANSEESDSVFSEN CCCCCHHCCCCCCCC | 26657352 | ||
| 191 | Phosphorylation | ANSEESDSVFSENTE CCCHHCCCCCCCCHH | 27251275 | ||
| 194 | Phosphorylation | EESDSVFSENTEDLQ HHCCCCCCCCHHHHH | 27251275 | ||
| 197 | Phosphorylation | DSVFSENTEDLQEQF CCCCCCCHHHHHHHH | 26471730 | ||
| 215 | O-linked_Glycosylation | KHHSHANSQANHAQG HHHHHHHHHHHHHHH | OGP | ||
| 226 | Phosphorylation | HAQGEQASFESFEEM HHHHHHHCHHHHHHH | 26091039 | ||
| 229 | Phosphorylation | GEQASFESFEEMLQD HHHHCHHHHHHHHHH | 26091039 | ||
| 246 | N-linked_Glycosylation | KVPESENNKTSNSSQ CCCCCCCCCCCCCHH | UniProtKB CARBOHYD | ||
| 248 | Phosphorylation | PESENNKTSNSSQVS CCCCCCCCCCCHHCC | - | ||
| 278 | Ubiquitination | MTLDLKTKFGSTADA CCCCCCHHCCCHHHE | 29967540 | ||
| 281 | Phosphorylation | DLKTKFGSTADALVS CCCHHCCCHHHEECC | 18669648 | ||
| 282 | Phosphorylation | LKTKFGSTADALVSD CCHHCCCHHHEECCC | 20068231 | ||
| 288 | Phosphorylation | STADALVSDDETTRL CHHHEECCCHHHHHH | 18669648 | ||
| 292 | Phosphorylation | ALVSDDETTRLVTSL EECCCHHHHHHEECC | 20639409 | ||
| 293 | Phosphorylation | LVSDDETTRLVTSLE ECCCHHHHHHEECCC | 18669648 | ||
| 297 | Phosphorylation | DETTRLVTSLEDDFD HHHHHHEECCCCCCC | 29691806 | ||
| 298 | Phosphorylation | ETTRLVTSLEDDFDE HHHHHEECCCCCCCH | 26657352 | ||
| 350 | Phosphorylation | AKSGVEKYPTDKEQN CCCCCCCCCCCHHCC | 26471730 | ||
| 350 | Ubiquitination | AKSGVEKYPTDKEQN CCCCCCCCCCCHHCC | 29901268 | ||
| 352 | Phosphorylation | SGVEKYPTDKEQNSN CCCCCCCCCHHCCCC | 26471730 | ||
| 355 | Ubiquitination | EKYPTDKEQNSNEED CCCCCCHHCCCCCCC | 21890473 | ||
| 355 (in isoform 4) | Ubiquitination | - | 21890473 | ||
| 358 | Phosphorylation | PTDKEQNSNEEDKVQ CCCHHCCCCCCCCEE | 29255136 | ||
| 363 | Ubiquitination | QNSNEEDKVQLTVPP CCCCCCCCEEEECCC | 33845483 | ||
| 367 | O-linked_Glycosylation | EEDKVQLTVPPGIKN CCCCEEEECCCCCCC | OGP | ||
| 381 | O-linked_Glycosylation | NDDKNILTTWGDTIF CCCCCEEECCCCCEE | OGP | ||
| 382 | O-linked_Glycosylation | DDKNILTTWGDTIFS CCCCEEECCCCCEEE | OGP | ||
| 382 | Phosphorylation | DDKNILTTWGDTIFS CCCCEEECCCCCEEE | 21082442 | ||
| 384 | Ubiquitination | KNILTTWGDTIFSIV CCEEECCCCCEEEEE | 29967540 | ||
| 389 | O-linked_Glycosylation | TWGDTIFSIVTGGEE CCCCCEEEEECCCCC | OGP | ||
| 400 | Phosphorylation | GGEETRDTMDLESSS CCCCCCCCCCCCCCC | 25850435 | ||
| 405 | Phosphorylation | RDTMDLESSSSEEEK CCCCCCCCCCCHHHH | 30278072 | ||
| 406 | Phosphorylation | DTMDLESSSSEEEKE CCCCCCCCCCHHHHC | 30278072 | ||
| 407 | Phosphorylation | TMDLESSSSEEEKED CCCCCCCCCHHHHCC | 30278072 | ||
| 408 | Phosphorylation | MDLESSSSEEEKEDD CCCCCCCCHHHHCCC | 30278072 | ||
| 423 | Phosphorylation | DDALVPDSKQGKPQS CCCCCCCCCCCCCCC | 25002506 | ||
| 436 | Ubiquitination | QSATDYSDPDNVDDG CCCCCCCCCCCCCCC | 24816145 | ||
| 451 | Acetylation | LFIVDIPKTNNDKEV EEEEEECCCCCCCCC | 7712331 | ||
| 475 | Ubiquitination | GRGVQESKRGLVQDK CCCHHHHHCCCCCCC | 29967540 | ||
| 505 | Ubiquitination | SVHSNNLNSMPAAEK CHHCCCCCCCCHHHH | 24816145 | ||
| 524 | Phosphorylation | LKSAYDDTENDLKGA HHHHCCCCCCHHHHH | - | ||
| 554 | Phosphorylation | EQILEGGSESESAQK CCCCCCCCCCHHHHH | 28270605 | ||
| 556 | Phosphorylation | ILEGGSESESAQKAA CCCCCCCCHHHHHHH | 25850435 | ||
| 558 | Phosphorylation | EGGSESESAQKAAGN CCCCCCHHHHHHHHC | 28270605 | ||
| 563 | Phosphorylation | SESAQKAAGNQMNDR CHHHHHHHHCCCCHH | 32142685 | ||
| 576 | Ubiquitination | DRKIQQESLGSAPLM HHHHCHHHHCCCCCC | 29967540 | ||
| 579 | O-linked_Glycosylation | IQQESLGSAPLMGDD HCHHHHCCCCCCCCC | 30059200 | ||
| 589 | N-linked_Glycosylation | LMGDDHPNASRDSVE CCCCCCCCCCCCCCC | 19159218 | ||
| 591 | O-linked_Glycosylation | GDDHPNASRDSVEGD CCCCCCCCCCCCCCC | 30059200 | ||
| 591 | Phosphorylation | GDDHPNASRDSVEGD CCCCCCCCCCCCCCC | 23312004 | ||
| 608 | Phosphorylation | VNGAKLHTLSVEHQR HCCCEEEEECHHHHH | 24275569 | ||
| 610 | Phosphorylation | GAKLHTLSVEHQREE CCEEEEECHHHHHHH | 24275569 | ||
| 613 | Phosphorylation | LHTLSVEHQREELKE EEEECHHHHHHHHHH | 32142685 | ||
| 623 | Phosphorylation | EELKEELVLKTQNQP HHHHHHHHHHCCCCC | 32645325 | ||
| 669 | Ubiquitination | DVAATASKQMSEKIR HHHHHHHHHHHHHCC | 24816145 | ||
| 678 | Phosphorylation | MSEKIRLSEGEAKED HHHHCCCCCCCCCCC | 23186163 | ||
| 686 | Phosphorylation | EGEAKEDSLDEEFFH CCCCCCCCCCHHHHH | 26657352 | ||
| 697 | Sulfoxidation | EFFHHKAMQGTEVGQ HHHHHHHCCCCCCCC | 21406390 | ||
| 700 | O-linked_Glycosylation | HHKAMQGTEVGQTDQ HHHHCCCCCCCCCCC | OGP | ||
| 708 | O-linked_Glycosylation | EVGQTDQTDSTGGPA CCCCCCCCCCCCCCC | OGP | ||
| 711 | O-linked_Glycosylation | QTDQTDSTGGPAFLS CCCCCCCCCCCCHHH | OGP | ||
| 712 | Phosphorylation | TDQTDSTGGPAFLSK CCCCCCCCCCCHHHC | 32142685 | ||
| 725 | Phosphorylation | SKVEEDDYPSEELLE HCCCCCCCCCHHHHC | 23403867 | ||
| 727 | Phosphorylation | VEEDDYPSEELLEDE CCCCCCCCHHHHCCH | 19664994 | ||
| 740 | Ubiquitination | DENAINAKRSKEKNP CHHHHHHHHHCCCCC | 29967540 | ||
| 752 | Ubiquitination | KNPGNQGRQFDVNLQ CCCCCCCCCEEEEEE | 24816145 | ||
| 768 | O-linked_Glycosylation | PDRAVLGTIHPDPEI CCCEEECCCCCCCCH | 55826417 | ||
| 782 | O-linked_Glycosylation | IEESKQETSMILDSE HHHHHHHHEEEECCC | OGP | ||
| 782 | Ubiquitination | IEESKQETSMILDSE HHHHHHHHEEEECCC | 24816145 | ||
| 784 | Phosphorylation | ESKQETSMILDSEKT HHHHHHEEEECCCHH | 33259812 | ||
| 788 | Phosphorylation | ETSMILDSEKTSETA HHEEEECCCHHHHHH | - | ||
| 806 | Ubiquitination | VNTGGREPNTMVEKE CCCCCCCCCCCCCCC | 24816145 | ||
| 808 | Phosphorylation | TGGREPNTMVEKERP CCCCCCCCCCCCCCC | 33259812 | ||
| 828 | Phosphorylation | AQRPFERSDFSDSIK CCCCCCCCCCCCCEE | 26434776 | ||
| 831 | Phosphorylation | PFERSDFSDSIKIQT CCCCCCCCCCEEEEC | 26434776 | ||
| 833 | Phosphorylation | ERSDFSDSIKIQTPE CCCCCCCCEEEECCC | 23401153 | ||
| 838 | O-linked_Glycosylation | SDSIKIQTPELGEVF CCCEEEECCCHHHHH | 9941263 | ||
| 838 | Phosphorylation | SDSIKIQTPELGEVF CCCEEEECCCHHHHH | 26434776 | ||
| 864 | O-linked_Glycosylation | NPEEHLKTSGLAGEP CHHHHHHHCCCCCCC | 30059200 | ||
| 864 | Phosphorylation | NPEEHLKTSGLAGEP CHHHHHHHCCCCCCC | 27251275 | ||
| 865 | O-linked_Glycosylation | PEEHLKTSGLAGEPE HHHHHHHCCCCCCCC | 30059200 | ||
| 865 | Phosphorylation | PEEHLKTSGLAGEPE HHHHHHHCCCCCCCC | 27251275 | ||
| 876 | Phosphorylation | GEPEGELSKEDHENT CCCCCCCCHHHHCCH | 28355574 | ||
| 883 | Phosphorylation | SKEDHENTEKYMGTE CHHHHCCHHHHCCCC | 23927012 | ||
| 907 | O-linked_Glycosylation | EDDSFHWTPHTSVEP CCCCCCCCCCCCCCC | OGP | ||
| 910 | O-linked_Glycosylation | SFHWTPHTSVEPGHS CCCCCCCCCCCCCCC | OGP | ||
| 961 | Phosphorylation | EMSSKLKSAQQESLP HHHHHHHHHHHHCCC | 28258704 | ||
| 966 | Phosphorylation | LKSAQQESLPYNMEK HHHHHHHCCCCCHHH | 28258704 | ||
| 969 | Phosphorylation | AQQESLPYNMEKVLD HHHHCCCCCHHHHHH | - | ||
| 982 | Phosphorylation | LDKVFRASESQILSI HHHHHHHCHHHHHHH | 25954137 | ||
| 984 | Phosphorylation | KVFRASESQILSIAE HHHHHCHHHHHHHHH | 25693802 | ||
| 988 | Phosphorylation | ASESQILSIAEKMLD HCHHHHHHHHHHHHC | 25954137 | ||
| 1040 | O-linked_Glycosylation | STAEETATLVMAPPL CCHHHEEEEEECCCH | 55835381 | ||
| 1055 | Ubiquitination | EEGLGGAMEEMQPLH HCCCCHHHHHHCCCC | 33845483 | ||
| 1067 | Phosphorylation | PLHEDNFSREKTAEL CCCCCCCCCCCCEEE | 24275569 | ||
| 1069 | Ubiquitination | HEDNFSREKTAELNV CCCCCCCCCCEEECC | 29967540 | ||
| 1076 | Ubiquitination | EKTAELNVQVPEEPT CCCEEECCCCCCCCC | 29901268 | ||
| 1083 | O-linked_Glycosylation | VQVPEEPTHLDQRVI CCCCCCCCCCCHHHH | 55829077 | ||
| 1089 | Ubiquitination | PTHLDQRVIGDTHAS CCCCCHHHHCCCCHH | 29967540 | ||
| 1093 | O-linked_Glycosylation | DQRVIGDTHASEVSQ CHHHHCCCCHHHHCC | 55824969 | ||
| 1099 | O-linked_Glycosylation | DTHASEVSQKPNTEK CCCHHHHCCCCCCCC | 30059200 | ||
| 1104 | O-linked_Glycosylation | EVSQKPNTEKDLDPG HHCCCCCCCCCCCCC | 55824981 | ||
| 1110 | Ubiquitination | NTEKDLDPGPVTTED CCCCCCCCCCCCCCC | 29967540 | ||
| 1114 | O-linked_Glycosylation | DLDPGPVTTEDTPMD CCCCCCCCCCCCCCC | OGP | ||
| 1115 | O-linked_Glycosylation | LDPGPVTTEDTPMDA CCCCCCCCCCCCCCC | OGP | ||
| 1120 | Ubiquitination | VTTEDTPMDAIDANK CCCCCCCCCCCCCCC | 29967540 | ||
| 1158 | Acetylation | SFMFYLTKSLVATLP HHHHHHHHHHHHCCC | 11688313 | ||
| 1159 | Phosphorylation | FMFYLTKSLVATLPD HHHHHHHHHHHCCCC | 20363803 | ||
| 1163 | Phosphorylation | LTKSLVATLPDDVQP HHHHHHHCCCCCCCC | 20363803 | ||
| 1175 | Phosphorylation | VQPGPDFYGLPWKPV CCCCCCCCCCCCHHH | 20363803 | ||
| 1209 | Phosphorylation | LVVKDRVYQVTEQQI HHHHHHHHHHHHHHH | 25954137 | ||
| 1212 | Phosphorylation | KDRVYQVTEQQISEK HHHHHHHHHHHHHHH | 25954137 | ||
| 1217 | Phosphorylation | QVTEQQISEKLKTIM HHHHHHHHHHHHHHH | 25954137 | ||
| 1219 | 2-Hydroxyisobutyrylation | TEQQISEKLKTIMKE HHHHHHHHHHHHHHH | - | ||
| 1219 | Ubiquitination | TEQQISEKLKTIMKE HHHHHHHHHHHHHHH | 33845483 | ||
| 1221 | Ubiquitination | QQISEKLKTIMKENT HHHHHHHHHHHHHHH | - | ||
| 1228 | Phosphorylation | KTIMKENTELVQKLS HHHHHHHHHHHHHHH | 29978859 | ||
| 1233 | Ubiquitination | ENTELVQKLSNYEQK HHHHHHHHHHHHHHH | 29967540 | ||
| 1235 | Phosphorylation | TELVQKLSNYEQKIK HHHHHHHHHHHHHHH | 29978859 | ||
| 1237 | Phosphorylation | LVQKLSNYEQKIKES HHHHHHHHHHHHHHH | 29978859 | ||
| 1240 | Malonylation | KLSNYEQKIKESKKH HHHHHHHHHHHHHHH | 26320211 | ||
| 1240 | Ubiquitination | KLSNYEQKIKESKKH HHHHHHHHHHHHHHH | 29901268 | ||
| 1251 | Phosphorylation | SKKHVQETRKQNMIL HHHHHHHHHHHHCCC | - | ||
| 1253 | Ubiquitination | KHVQETRKQNMILSD HHHHHHHHHHCCCCH | 29967540 | ||
| 1259 | Phosphorylation | RKQNMILSDEAIKYK HHHHCCCCHHHHHCH | 21815630 | ||
| 1274 | Ubiquitination | DKIKTLEKNQEILDD HHHHHHHHHHHHHHH | 29967540 | ||
| 1284 | 2-Hydroxyisobutyrylation | EILDDTAKNLRVMLE HHHHHHHHHHHHHHH | - | ||
| 1284 | Ubiquitination | EILDDTAKNLRVMLE HHHHHHHHHHHHHHH | 29967540 | ||
| 1289 | Sulfoxidation | TAKNLRVMLESEREQ HHHHHHHHHHHHHHH | 21406390 | ||
| 1308 | 2-Hydroxyisobutyrylation | QDLISENKKSIEKLK HHHHHCCHHHHHHHH | - | ||
| 1308 | Ubiquitination | QDLISENKKSIEKLK HHHHHCCHHHHHHHH | 29901268 | ||
| 1313 | Ubiquitination | ENKKSIEKLKDVISM CCHHHHHHHHHHHCC | 21890473 | ||
| 1319 | Phosphorylation | EKLKDVISMNASEFS HHHHHHHCCCHHHHH | 29978859 | ||
| 1321 | Ubiquitination | LKDVISMNASEFSEV HHHHHCCCHHHHHHH | 33845483 | ||
| 1323 | Phosphorylation | DVISMNASEFSEVQI HHHCCCHHHHHHHHH | 29978859 | ||
| 1326 | Phosphorylation | SMNASEFSEVQIALN CCCHHHHHHHHHHHH | 29978859 | ||
| 1338 | Phosphorylation | ALNEAKLSEEKVKSE HHHHHHCCHHHHHHH | 29978859 | ||
| 1342 | Ubiquitination | AKLSEEKVKSECHRV HHCCHHHHHHHHHHH | 29967540 | ||
| 1394 | Ubiquitination | SQKDLEVALTHKDDN HHHHHHHHHHCCCCH | 24816145 | ||
| 1406 | Phosphorylation | DDNINALTNCITQLN CCHHHHHHHHHHHHH | 28102081 | ||
| 1410 | Phosphorylation | NALTNCITQLNLLEC HHHHHHHHHHHHHCC | 28102081 | ||
| 1413 | Ubiquitination | TNCITQLNLLECESE HHHHHHHHHHCCCCC | 29901268 | ||
| 1418 | Ubiquitination | QLNLLECESESEGQN HHHHHCCCCCCCCCC | 21890473 | ||
| 1418 (in isoform 2) | Ubiquitination | - | 21890473 | ||
| 1419 | Phosphorylation | LNLLECESESEGQNK HHHHCCCCCCCCCCC | 22468782 | ||
| 1421 | Phosphorylation | LLECESESEGQNKGG HHCCCCCCCCCCCCC | 22468782 | ||
| 1426 | Ubiquitination | SESEGQNKGGNDSDE CCCCCCCCCCCCHHH | 33845483 | ||
| 1431 | Phosphorylation | QNKGGNDSDELANGE CCCCCCCHHHHHCCC | 25159151 | ||
| 1433 | Ubiquitination | KGGNDSDELANGEVG CCCCCHHHHHCCCCC | 29967540 | ||
| 1447 | Ubiquitination | GGDRNEKMKNQIKQM CCCHHHHHHHHHHHH | 29967540 | ||
| 1460 | Phosphorylation | QMMDVSRTQTAISVV HHHHHHHHHHHHHHH | 20068231 | ||
| 1462 | Phosphorylation | MDVSRTQTAISVVEE HHHHHHHHHHHHHHH | 20068231 | ||
| 1465 | Phosphorylation | SRTQTAISVVEEDLK HHHHHHHHHHHHHHH | 27499020 | ||
| 1472 | Ubiquitination | SVVEEDLKLLQLKLR HHHHHHHHHHHHHHH | 29901268 | ||
| 1477 | Ubiquitination | DLKLLQLKLRASVST HHHHHHHHHHHHHHC | 22817900 | ||
| 1477 (in isoform 1) | Ubiquitination | - | 21890473 | ||
| 1483 | Phosphorylation | LKLRASVSTKCNLED HHHHHHHHCCCCHHH | 23186163 | ||
| 1484 | Phosphorylation | KLRASVSTKCNLEDQ HHHHHHHCCCCHHHH | 23186163 | ||
| 1485 | Ubiquitination | LRASVSTKCNLEDQV HHHHHHCCCCHHHHH | 33845483 | ||
| 1496 | Ubiquitination | EDQVKKLEDDRNSLQ HHHHHHHHHHHHHHH | 22817900 | ||
| 1499 | Ubiquitination | VKKLEDDRNSLQAAK HHHHHHHHHHHHHHH | 24816145 | ||
| 1501 | Phosphorylation | KLEDDRNSLQAAKAG HHHHHHHHHHHHHHC | 27067055 | ||
| 1501 | Ubiquitination | KLEDDRNSLQAAKAG HHHHHHHHHHHHHHC | 21890473 | ||
| 1506 | Ubiquitination | RNSLQAAKAGLEDEC HHHHHHHHHCCHHHH | 29967540 | ||
| 1514 | Phosphorylation | AGLEDECKTLRQKVE HCCHHHHHHHHHHHH | 32142685 | ||
| 1515 | Phosphorylation | GLEDECKTLRQKVEI CCHHHHHHHHHHHHH | - | ||
| 1538 | Ubiquitination | EMALQKKLSQEEYER HHHHHHHHCHHHHHH | 29967540 | ||
| 1539 | Phosphorylation | MALQKKLSQEEYERQ HHHHHHHCHHHHHHH | 25159151 | ||
| 1543 | Phosphorylation | KKLSQEEYERQEREH HHHCHHHHHHHHHHH | 28102081 | ||
| 1553 | Phosphorylation | QEREHRLSAADEKAV HHHHHHHCHHHHHHH | 29214152 | ||
| 1555 | Ubiquitination | REHRLSAADEKAVSA HHHHHCHHHHHHHHH | 22817900 | ||
| 1558 | 2-Hydroxyisobutyrylation | RLSAADEKAVSAAEE HHCHHHHHHHHHHHH | - | ||
| 1558 | Ubiquitination | RLSAADEKAVSAAEE HHCHHHHHHHHHHHH | 24816145 | ||
| 1560 | Ubiquitination | SAADEKAVSAAEEVK CHHHHHHHHHHHHHH | 21890473 | ||
| 1568 | Phosphorylation | SAAEEVKTYKRRIEE HHHHHHHHHHHHHHH | 24144214 | ||
| 1569 | Phosphorylation | AAEEVKTYKRRIEEM HHHHHHHHHHHHHHH | 19658100 | ||
| 1571 | Phosphorylation | EEVKTYKRRIEEMED HHHHHHHHHHHHHHH | 32142685 | ||
| 1581 | Phosphorylation | EEMEDELQKTERSFK HHHHHHHHHHHHHHH | 32645325 | ||
| 1582 | Ubiquitination | EMEDELQKTERSFKN HHHHHHHHHHHHHHH | 24816145 | ||
| 1596 | 2-Hydroxyisobutyrylation | NQIATHEKKAHENWL HHHHHHHHHHHHHHH | - | ||
| 1597 | Ubiquitination | QIATHEKKAHENWLK HHHHHHHHHHHHHHH | 29967540 | ||
| 1619 | Phosphorylation | IAEEKREAANLRHKL HHHHHHHHHHHHHHH | 32142685 | ||
| 1662 | Phosphorylation | PPRRGPLSQNGSFGP CCCCCCCCCCCCCCC | 26074081 | ||
| 1666 | Phosphorylation | GPLSQNGSFGPSPVS CCCCCCCCCCCCCCC | 26699800 | ||
| 1670 | Phosphorylation | QNGSFGPSPVSGGEC CCCCCCCCCCCCCCC | 22617229 | ||
| 1673 | Phosphorylation | SFGPSPVSGGECSPP CCCCCCCCCCCCCCC | 22617229 | ||
| 1676 | Phosphorylation | PSPVSGGECSPPLTV CCCCCCCCCCCCCCC | 32142685 | ||
| 1678 | Phosphorylation | PVSGGECSPPLTVEP CCCCCCCCCCCCCCC | 23401153 | ||
| 1682 | Phosphorylation | GECSPPLTVEPPVRP CCCCCCCCCCCCCCC | 30266825 | ||
| 1686 | Phosphorylation | PPLTVEPPVRPLSAT CCCCCCCCCCCCCEE | 32645325 | ||
| 1691 | Phosphorylation | EPPVRPLSATLNRRD CCCCCCCCEECCCCC | 23898821 | ||
| 1693 | Phosphorylation | PVRPLSATLNRRDMP CCCCCCEECCCCCCC | 23898821 | ||
| 1702 | Phosphorylation | NRRDMPRSEFGSVDG CCCCCCHHHCCCCCC | 30266825 | ||
| 1706 | Phosphorylation | MPRSEFGSVDGPLPH CCHHHCCCCCCCCCC | 23401153 | ||
| 1717 | Phosphorylation | PLPHPRWSAEASGKP CCCCCCCCHHHCCCC | 25219547 | ||
| 1721 | Phosphorylation | PRWSAEASGKPSPSD CCCCHHHCCCCCCCC | 23927012 | ||
| 1723 | Ubiquitination | WSAEASGKPSPSDPG CCHHHCCCCCCCCCC | - | ||
| 1725 | Phosphorylation | AEASGKPSPSDPGSG HHHCCCCCCCCCCCC | 25159151 | ||
| 1727 | Phosphorylation | ASGKPSPSDPGSGTA HCCCCCCCCCCCCCC | 23927012 | ||
| 1731 | Phosphorylation | PSPSDPGSGTATMMN CCCCCCCCCCCEECC | 23927012 | ||
| 1733 | Phosphorylation | PSDPGSGTATMMNSS CCCCCCCCCEECCCC | 23927012 | ||
| 1735 | Phosphorylation | DPGSGTATMMNSSSR CCCCCCCEECCCCCC | 30278072 | ||
| 1739 | Phosphorylation | GTATMMNSSSRGSSP CCCEECCCCCCCCCC | 23401153 | ||
| 1740 | Phosphorylation | TATMMNSSSRGSSPT CCEECCCCCCCCCCC | 22167270 | ||
| 1740 | Ubiquitination | TATMMNSSSRGSSPT CCEECCCCCCCCCCC | 24816145 | ||
| 1741 | Phosphorylation | ATMMNSSSRGSSPTR CEECCCCCCCCCCCE | 22167270 | ||
| 1742 | Phosphorylation | TMMNSSSRGSSPTRV EECCCCCCCCCCCEE | 33259812 | ||
| 1744 | Phosphorylation | MNSSSRGSSPTRVLD CCCCCCCCCCCEEEC | 30278072 | ||
| 1745 | Phosphorylation | NSSSRGSSPTRVLDE CCCCCCCCCCEEECC | 23401153 | ||
| 1747 | Phosphorylation | SSRGSSPTRVLDEGK CCCCCCCCEEECCCC | 30278072 | ||
| 1764 | Ubiquitination | MAPKGPPPFPGVPLM CCCCCCCCCCCCCCC | 24816145 | ||
| 1784 | Asymmetric dimethylarginine | GPVPPPIRYGPPPQL CCCCCCCCCCCCCCC | - | ||
| 1784 | Methylation | GPVPPPIRYGPPPQL CCCCCCCCCCCCCCC | - | ||
| 1809 | Dimethylation | PPFGPGMRPPLGLRE CCCCCCCCCCCCHHH | - | ||
| 1809 | Methylation | PPFGPGMRPPLGLRE CCCCCCCCCCCCHHH | 115390663 | ||
| 1845 | Ubiquitination | GHAPFRPLGSLGPRE CCCCCCCCCCCCCCC | 24816145 | ||
| 1847 | Phosphorylation | APFRPLGSLGPREYF CCCCCCCCCCCCCCC | 33259812 | ||
| 1859 | Methylation | EYFIPGTRLPPPTHG CCCCCCCCCCCCCCC | 115483225 | ||
| 1877 | Methylation | YPPPPAVRDLLPSGS CCCCCHHHHCCCCCC | 115483233 | ||
| 1882 | Phosphorylation | AVRDLLPSGSRDEPP HHHHCCCCCCCCCCC | 23403867 | ||
| 1884 | Phosphorylation | RDLLPSGSRDEPPPA HHCCCCCCCCCCCCC | 26657352 | ||
| 1892 | Phosphorylation | RDEPPPASQSTSQDC CCCCCCCCCCCCHHH | 23927012 | ||
| 1894 | Phosphorylation | EPPPASQSTSQDCSQ CCCCCCCCCCHHHHH | 23663014 | ||
| 1895 | Phosphorylation | PPPASQSTSQDCSQA CCCCCCCCCHHHHHH | 23663014 | ||
| 1896 | Phosphorylation | PPASQSTSQDCSQAL CCCCCCCCHHHHHHH | 23927012 | ||
| 1900 | Phosphorylation | QSTSQDCSQALKQSP CCCCHHHHHHHHHCC | 23927012 | ||
| 1904 | Ubiquitination | QDCSQALKQSP---- HHHHHHHHHCC---- | 24816145 | ||
| 1906 | Phosphorylation | CSQALKQSP------ HHHHHHHCC------ | 23927012 | ||
| 1928 | Ubiquitination | ---------------------------- ---------------------------- | 24816145 | ||
| 1930 | Phosphorylation | ------------------------------ ------------------------------ | 33259812 | ||
| 1952 | Ubiquitination | ---------------------------------------------------- ---------------------------------------------------- | 24816145 |
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of TGO1_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of TGO1_HUMAN !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| CRTAP_HUMAN | CRTAP | physical | 26186194 | |
| SIG12_HUMAN | SIGLEC12 | physical | 26186194 | |
| CTGE5_HUMAN | CTAGE5 | physical | 26186194 | |
| P3H1_HUMAN | P3H1 | physical | 26186194 | |
| MTMRE_HUMAN | MTMR14 | physical | 26186194 | |
| SIG12_HUMAN | SIGLEC12 | physical | 28514442 | |
| CRTAP_HUMAN | CRTAP | physical | 28514442 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
loading...
