CLV1_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: CLV1_ARATH
• UniProt AC: Q9SYQ8
• Protein Name: Receptor protein kinase CLAVATA1
• Gene Name: CLV1
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 980
• Subcellular Localization: Cell membrane ; Single-pass type I membrane protein .
• Protein Description: Involved in the detection of CLV3 and CLV3-like (CLE) peptides, that act as extracellular signals regulating meristem maintenance. Acts with CLV3p as a ligand-receptor pair in a signal transduction pathway coordinating growth between adjacent meristematic regions and controlling the balance between meristem cell proliferation and differentiation..
• Protein Sequence: MAMRLLKTHLLFLHLYLFFSPCFAYTDMEVLLNLKSSMIGPKGHGLHDWIHSSSPDAHCSFSGVSCDDDARVISLNVSFTPLFGTISPEIGMLTHLVNLTLAANNFTGELPLEMKSLTSLKVLNISNNGNLTGTFPGEILKAMVDLEVLDTYNNNFNGKLPPEMSELKKLKYLSFGGNFFSGEIPESYGDIQSLEYLGLNGAGLSGKSPAFLSRLKNLREMYIGYYNSYTGGVPPEFGGLTKLEILDMASCTLTGEIPTSLSNLKHLHTLFLHINNLTGHIPPELSGLVSLKSLDLSINQLTGEIPQSFINLGNITLINLFRNNLYGQIPEAIGELPKLEVFEVWENNFTLQLPANLGRNGNLIKLDVSDNHLTGLIPKDLCRGEKLEMLILSNNFFFGPIPEELGKCKSLTKIRIVKNLLNGTVPAGLFNLPLVTIIELTDNFFSGELPVTMSGDVLDQIYLSNNWFSGEIPPAIGNFPNLQTLFLDRNRFRGNIPREIFELKHLSRINTSANNITGGIPDSISRCSTLISVDLSRNRINGEIPKGINNVKNLGTLNISGNQLTGSIPTGIGNMTSLTTLDLSFNDLSGRVPLGGQFLVFNETSFAGNTYLCLPHRVSCPTRPGQTSDHNHTALFSPSRIVITVIAAITGLILISVAIRQMNKKKNQKSLAWKLTAFQKLDFKSEDVLECLKEENIIGKGGAGIVYRGSMPNNVDVAIKRLVGRGTGRSDHGFTAEIQTLGRIRHRHIVRLLGYVANKDTNLLLYEYMPNGSLGELLHGSKGGHLQWETRHRVAVEAAKGLCYLHHDCSPLILHRDVKSNNILLDSDFEAHVADFGLAKFLVDGAASECMSSIAGSYGYIAPEYAYTLKVDEKSDVYSFGVVLLELIAGKKPVGEFGEGVDIVRWVRNTEEEITQPSDAAIVVAIVDPRLTGYPLTSVIHVFKIAMMCVEEEAAARPTMREVVHMLTNPPKSVANLIAF

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
76	N-linked_Glycosylation	DARVISLNVSFTPLF CCCEEEEEEEEECCC	22.16	-
98	N-linked_Glycosylation	GMLTHLVNLTLAANN HHHHHHHHHHHHHCC	33.40	-
105	N-linked_Glycosylation	NLTLAANNFTGELPL HHHHHHCCCCCCCCC	31.00	-
124	N-linked_Glycosylation	LTSLKVLNISNNGNL CCEEEEEEECCCCCC	38.33	-
130	N-linked_Glycosylation	LNISNNGNLTGTFPG EEECCCCCCCCCCCH	36.23	-
276	N-linked_Glycosylation	TLFLHINNLTGHIPP HHEEHHHHCCCCCCH	38.07	-
314	N-linked_Glycosylation	QSFINLGNITLINLF HHHHHCCCEEEEEHH	27.51	-
348	N-linked_Glycosylation	VFEVWENNFTLQLPA EEEEECCCEEEEECC	21.55	-
422	N-linked_Glycosylation	RIVKNLLNGTVPAGL HHHHHHHCCCCCCCC	47.45	-
510	N-linked_Glycosylation	LKHLSRINTSANNIT HHHHHHCCCCCCCCC	27.20	-
515	N-linked_Glycosylation	RINTSANNITGGIPD HCCCCCCCCCCCCCC	32.68	-
558	N-linked_Glycosylation	VKNLGTLNISGNQLT CEECEEEEECCCEEE	26.64	-
574	N-linked_Glycosylation	SIPTGIGNMTSLTTL CCCCCCCCCCCCEEE	28.74	-
602	N-linked_Glycosylation	GGQFLVFNETSFAGN CCEEEEEECCCCCCC	44.12	-
631	N-linked_Glycosylation	PGQTSDHNHTALFSP CCCCCCCCCCCCCCH	38.91	-
766	Phosphorylation	KDTNLLLYEYMPNGS CCCCEEEEEECCCCC	12.65	-
804	Phosphorylation	EAAKGLCYLHHDCSP HHHCCHHHHCCCCCC	17.70	-
852	Phosphorylation	GAASECMSSIAGSYG CHHHHHHHHHHHHCC	30.19	-
860	Phosphorylation	SIAGSYGYIAPEYAY HHHHHCCEECCCEEE	5.91	-
867	Phosphorylation	YIAPEYAYTLKVDEK EECCCEEEEEEECCC	16.23	-
868	Phosphorylation	IAPEYAYTLKVDEKS ECCCEEEEEEECCCC	16.36	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of CLV1_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of CLV1_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of CLV1_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
P2C70_ARATH	KAPP	physical	17302430
P2C70_ARATH	KAPP	physical	9701578
CLV1_ARATH	CLV1	physical	9294234
P2C70_ARATH	KAPP	physical	9294234
CLV3_ARATH	CLV3	physical	18202283
CLV1_ARATH	CLV1	physical	19933383
CLV1_ARATH	CLV1	physical	20626648
BAME1_ARATH	BAM1	physical	20626648
BAME2_ARATH	BAM2	physical	20626648
CLV2_ARATH	CLV2	physical	20626648
CLV2_ARATH	CLV2	physical	20965998
CRN_ARATH	CRN	physical	20965998
RPK2_ARATH	RPK2	physical	20965998
CDPK1_ARATH	CPK1	physical	22737156
ACR4L_ARATH	CR4	physical	23394827
CCI1_ARATH	CPI1	physical	23776660
CLE2_ARATH	CLE2	physical	19525968
CLV3_ARATH	CLV3	physical	19525968
CLV3_ARATH	CLV3	physical	25754504

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.