CLU_DROME - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: CLU_DROME
• UniProt AC: A1ZAB5
• Protein Name: Protein clueless {ECO:0000255|HAMAP-Rule:MF_03013}
• Gene Name: clu {ECO:0000255|HAMAP-Rule:MF_03013}
• Organism: Drosophila melanogaster (Fruit fly).
• Sequence Length: 1448
• Subcellular Localization: Cytoplasm .
• Protein Description: mRNA-binding protein involved in proper cytoplasmic distribution of mitochondria..
• Protein Sequence: MALETEAKNSNATATGDATATATKASGKAKENNNTAGGKKNLNPNSNQQNSNQNLVNGNGTAADGPAAKKKGKKNRNKSPTEPTTEAVLSNGHAEKPTVVDAVEDNADTNANVEKPQEGGAPDAEADGDDIDLDALQDIGITVNISSPGADLLCVQLSSMELVQEIHQLLMDREETCHRTCFSLQLDNVTLDNFAELKSINNLEQGSTIKVVEEPYTMREARIHVRHVRDLLKNLDPADAYNGIDCTSLTYLNTITQGDLLDKKRTRPDSVDCTPPEYVTPGVSDPPILPLHPNVKNAKGPQALKVLTTSAWNPPPGPRKLHGDLMYLYVVTMEDKRFHISACSKGFFINQSTDDTFNPKPDNPSHLSHSLIDLLSHISPSFRRAFQTIQKRRTMRHAFERVATPYQVYQWAAPILEHTVDAIRAEDAFSSKLGYEEHIPGQTRDWNEELQTTRELPRKTLPERLLRERAIFKVHGDFVTAATRGAMAVIDGNVLAINPGEDTKMQMFIWNNIFFSMGFDVRDHYKELGGDAAAFVAPRYDLHGVRVYNAVDIEGLYTLGTVVVDYRGYRVTAQSIIPGILEREQEQSVVYGSIDFGKTVLSHPKYLELLRQAGKHLKILPHVVLNERDEPVELCSSVECKGIIGNDGRHYILDLLRTFPPDVNFLKLQDVQLSKELVDMGFPIEHRHKLCCLRQELLEAFIEDRHVNFIRIAAARLQQLTTIKQSEKSEANPVPALEGAEAASKVNGAEKPDDKEKKNEEEEKKERSTSGEARAAAIVNAIREAQSNVATSNEVQAAEVVKRACAAVGSLKEKEFDFRFNPDVFSPGIRHADGEEGTSLAKQKVLVQEAAEFLVLKQIPAFIKEHMSHSSSPIDGQSLTESLHSHGINVRYLGKVIKILSQMPRMDYLHRIAVLELIVRATKHIYYTYMQNTEPLHLSAAISHFLNCLLTNGPVNPAVSSEEAHKKRGNGGKHNKHKSSKGGKGQQQQQTTGNQNGSSSGSSNSSSASDWTLMTPRSLWQQIRKEAKVYWDWELDCDSIETAVSKYGILRISLMRAFCLKVGIQVLLREYNFESKHKPTFGDDDIVNVFPIVKHISPRATDAYNFYTTGQAKIQQGLFKEGYELISGALNLLNNVFGALHQENGSCLRMLARLSYLLGDAQDALAIQQRAVIMSERVNGMDHPSTILEYTHLSLYSFANGHVGMSLKLLYRARYLMVLICGEDHPEVALIDSNISLILHALGEYELSLRFIEHALKLNLKYFGDKDMHVALSYHLMARTQSCMGDFRSALNNEKETYSFYKSQLGENHEKTRDSAECLRLLTQQAVLLQRKMNDIYSSGKLTSDLPPIHITPPSMGSVLDMLNTINGILFVKISRKDIVKVRSEIEKHFKTDSTENEVNDAINSIVAAANNNGEAEDAVSKDIKEQPEAGKQLTNGDKAAATEATSS

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
79	Phosphorylation	GKKNRNKSPTEPTTE CCCCCCCCCCCCCHH		19429919
81	Phosphorylation	KNRNKSPTEPTTEAV CCCCCCCCCCCHHHH		19429919
84	Phosphorylation	NKSPTEPTTEAVLSN CCCCCCCCHHHHHCC		19429919
85	Phosphorylation	KSPTEPTTEAVLSNG CCCCCCCHHHHHCCC		19429919
270	Phosphorylation	KKRTRPDSVDCTPPE CCCCCCCCCCCCCCC		18327897

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of CLU_DROME !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of CLU_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of CLU_DROME !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
SICK_DROME	sick	physical	22036573
RL7A_DROME	RpL7A	physical	26834020
VDAC_DROME	porin	physical	26035866
TERA_DROME	TER94	physical	26931463
CLU_DROME	clu	physical	26834020
EIF3B_DROME	eIF3-S9	physical	26834020
RS4_DROME	RpS4	physical	26834020
RS7_DROME	RpS7	physical	26834020
APKC_DROME	aPKC	physical	23835532

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.