| UniProt ID | CK054_HUMAN | |
|---|---|---|
| UniProt AC | Q9H0W9 | |
| Protein Name | Ester hydrolase C11orf54 | |
| Gene Name | C11orf54 | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 315 | |
| Subcellular Localization | Nucleus . | |
| Protein Description | Exhibits ester hydrolase activity on the substrate p-nitrophenyl acetate.. | |
| Protein Sequence | MACAEFSFHVPSLEELAGVMQKGLKDNFADVQVSVVDCPDLTKEPFTFPVKGICGKTRIAEVGGVPYLLPLVNQKKVYDLNKIAKEIKLPGAFILGAGAGPFQTLGFNSEFMPVIQTESEHKPPVNGSYFAHVNPADGGCLLEKYSEKCHDFQCALLANLFASEGQPGKVIEVKAKRRTGPLNFVTCMRETLEKHYGNKPIGMGGTFIIQKGKVKSHIMPAEFSSCPLNSDEEVNKWLHFYEMKAPLVCLPVFVSRDPGFDLRLEHTHFFSRHGEGGHYHYDTTPDIVEYLGYFLPAEFLYRIDQPKETHSIGRD | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 12 | Phosphorylation | EFSFHVPSLEELAGV EEEEECCCHHHHHHH | 47.53 | 24275569 | |
| 47 | O-linked_Glycosylation | DLTKEPFTFPVKGIC CCCCCCCCCCCCCCC | 37.43 | 29351928 | |
| 47 | Phosphorylation | DLTKEPFTFPVKGIC CCCCCCCCCCCCCCC | 37.43 | 26074081 | |
| 56 (in isoform 2) | Ubiquitination | - | 30.16 | 21906983 | |
| 57 | Phosphorylation | VKGICGKTRIAEVGG CCCCCCCEEEEEECC | 16.76 | - | |
| 57 | O-linked_Glycosylation | VKGICGKTRIAEVGG CCCCCCCEEEEEECC | 16.76 | 29351928 | |
| 75 (in isoform 3) | Ubiquitination | - | 38.72 | 21906983 | |
| 75 (in isoform 1) | Ubiquitination | - | 38.72 | 21906983 | |
| 75 | Acetylation | LLPLVNQKKVYDLNK EEHHCCCCCEECHHH | 38.72 | 25953088 | |
| 75 | Ubiquitination | LLPLVNQKKVYDLNK EEHHCCCCCEECHHH | 38.72 | 2190698 | |
| 76 | Ubiquitination | LPLVNQKKVYDLNKI EHHCCCCCEECHHHH | 35.94 | - | |
| 76 | Acetylation | LPLVNQKKVYDLNKI EHHCCCCCEECHHHH | 35.94 | 24886927 | |
| 78 | Phosphorylation | LVNQKKVYDLNKIAK HCCCCCEECHHHHHH | 24.48 | 29496907 | |
| 82 | Ubiquitination | KKVYDLNKIAKEIKL CCEECHHHHHHHCCC | 51.87 | - | |
| 82 | Acetylation | KKVYDLNKIAKEIKL CCEECHHHHHHHCCC | 51.87 | 23236377 | |
| 117 | O-linked_Glycosylation | EFMPVIQTESEHKPP CEECEEECCCCCCCC | 30.29 | 29351928 | |
| 224 | Phosphorylation | HIMPAEFSSCPLNSD EECCCEECCCCCCCH | 23.65 | 28857561 | |
| 225 | Phosphorylation | IMPAEFSSCPLNSDE ECCCEECCCCCCCHH | 25.69 | 28857561 | |
| 236 | Acetylation | NSDEEVNKWLHFYEM CCHHHHHHHHHHHHC | 57.20 | 25038526 | |
| 263 | Methylation | RDPGFDLRLEHTHFF CCCCCCEEEEEEEEE | 39.61 | - | |
| 279 | Phosphorylation | RHGEGGHYHYDTTPD CCCCCCCCCCCCCHH | 12.83 | 22817900 | |
| 281 | Phosphorylation | GEGGHYHYDTTPDIV CCCCCCCCCCCHHHH | 14.07 | 24043423 | |
| 283 | Phosphorylation | GGHYHYDTTPDIVEY CCCCCCCCCHHHHHH | 32.82 | 24043423 | |
| 284 | Phosphorylation | GHYHYDTTPDIVEYL CCCCCCCCHHHHHHH | 18.96 | 24043423 | |
| 290 | Phosphorylation | TTPDIVEYLGYFLPA CCHHHHHHHCHHCCH | 8.43 | 24043423 | |
| 293 | Phosphorylation | DIVEYLGYFLPAEFL HHHHHHCHHCCHHHH | 10.19 | 24043423 | |
| 301 | Phosphorylation | FLPAEFLYRIDQPKE HCCHHHHHCCCCCCC | 15.73 | 24043423 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of CK054_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of CK054_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of CK054_HUMAN !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| A4_HUMAN | APP | physical | 21832049 | |
| PCH2_HUMAN | TRIP13 | physical | 19060904 | |
| VAC14_HUMAN | VAC14 | physical | 25416956 | |
| ADIP_HUMAN | SSX2IP | physical | 25416956 | |
| TCPB_HUMAN | CCT2 | physical | 26186194 | |
| BCAT2_HUMAN | BCAT2 | physical | 26344197 | |
| FKBP2_HUMAN | FKBP2 | physical | 26344197 | |
| NSF1C_HUMAN | NSFL1C | physical | 26344197 | |
| PIMT_HUMAN | PCMT1 | physical | 26344197 | |
| PRDX6_HUMAN | PRDX6 | physical | 26344197 | |
| SDF2_HUMAN | SDF2 | physical | 26344197 | |
| SPB3_HUMAN | SERPINB3 | physical | 26344197 | |
| SPB5_HUMAN | SERPINB5 | physical | 26344197 | |
| TKT_HUMAN | TKT | physical | 26344197 | |
| TPIS_HUMAN | TPI1 | physical | 26344197 | |
| WDR1_HUMAN | WDR1 | physical | 26344197 | |
| YKT6_HUMAN | YKT6 | physical | 26344197 | |
| TCPZ_HUMAN | CCT6A | physical | 28514442 | |
| TCPG_HUMAN | CCT3 | physical | 28514442 |
| Kegg Disease | ||||||
|---|---|---|---|---|---|---|
| There are no disease associations of PTM sites. | ||||||
| OMIM Disease | ||||||
| There are no disease associations of PTM sites. | ||||||
| Kegg Drug | ||||||
| There are no disease associations of PTM sites. | ||||||
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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