CHS2_SCHPO - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: CHS2_SCHPO
• UniProt AC: O74756
• Protein Name: Chitin synthase-like protein 2
• Gene Name: chs2
• Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
• Sequence Length: 926
• Subcellular Localization: Membrane ; Multi-pass membrane protein . Septum.
• Protein Description: Plays a role in septum formation. Has no chitin synthase activity..
• Protein Sequence: MSFQNPSYINAKHRSFLQPKDTQDSQDLRNWVSHSSVDEETAYSSSTLSSSSSKSFPCYDEYDEIKSPDDQKVEYMKTLRTLEEDAFSYTDSVYDFEERSFDEHEPPIPPLHKTGVFSVPLQPTHTVNSNSDDGYENSSKNEYLDFNSEISASPVNEPMTHSQSYTSIDRLNSSSSHYSKDVPLLCGSLTIDCPTPIDLRGMLGPFMQKNPDEASFLRYSAITCQPEDMNNNGLQLRTWSTGRDIQIAVCLTLSDEDLASFAISLSSIMNNLKHLCSRSKSRVWGNESWEKVLVCVVIDGRNTVHQNVLDLLASIGVYQPHIAKGRVNGKRTLSHMYEFTSTINVDEKLNLTTATGDGNVPMQMLLCVKDRRLGTYNSHRWFLNGIASLARPKVCLFVRNGARLGPTSIYHAWKAFDVDSTIGGMCGKTSIDTGKFGFRLLNPFIASQHFDQMIHNNLRLPYDSCMGYISNALNAIYGFRYVALQDSYPNPGPLADYFEQDQYEIPRRGILQSNAFLAQEQLLFWKVITRKDAKWHLQYVPEACATIEAPNSMAGILESKKSEINSSFSLAVYVIVDFFSLWTTRHKFFRFLLLTVQSLVFAIEKLVNFFSMANFFLAFYFVCNATSYSSLNPYGNWARPLFLVFEYILICLIFSQFMLAMGNRPRSCRVLLFISTALFSIIMIYFVFCVFYISLIPLHNSDNSEIVLGNNYFTTLIFSSLLILACYAFVSLICMDPFFIFTCIVQYILLMPTRIYTEQIYALCHLDDASISKDDNQQEFNFDTGITHCSMNDEGYTTISIPKANVLNSVYNSSLKNFSSSNDTSVYHDVQDHCYRKPQSYEDHYQDIRTRYVLVWAVSNLILAIVLIQVFDGMRFINNGYMKYIFWSIVAFTAWKTMGAVTFIATKIISRIANCVKSKLYIFNDP

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
131	Phosphorylation	THTVNSNSDDGYENS CCCCCCCCCCCCCCC	36.58	24763107

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of CHS2_SCHPO !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of CHS2_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of CHS2_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
CDC15_SCHPO	cdc15	genetic	16772338
MLR4_SCHPO	cdc4	genetic	16772338
MPIP_SCHPO	cdc25	physical	16772338
MYO52_SCHPO	myo52	physical	16772338
EXO70_SCHPO	exo70	physical	16772338
MLR4_SCHPO	cdc4	physical	16772338
MLR1_SCHPO	rlc1	physical	16772338
CDC11_SCHPO	cdc11	physical	16772338
CDC14_SCHPO	cdc14	physical	16772338
CDC16_SCHPO	cdc16	physical	16772338
MYO3_SCHPO	myp2	physical	16772338

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.