dbPTM

MLR1_SCHPO - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	MLR1_SCHPO
UniProt AC	Q9UUG5
Protein Name	Myosin regulatory light chain 1
Gene Name	rlc1
Organism	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length	184
Subcellular Localization	Cytoplasm.
Protein Description
Protein Sequence	MFSSKENSLGAKRAPFSSNTTSSQRVAAQAAKRASSGAFAQLTSSQIQELKEAFALLDKDGDGNIGREDVKTMLTSLNQDASEDSINHMFESINPPINLAAFLTAMGSMLCRISPRNDLLEAFSTFDDTQSGKIPISTMRDALSSMGDRMDPQEVESILRSYTSHGVFYYEKFVDAIAGSKDSN

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
35	Phosphorylation	AQAAKRASSGAFAQL HHHHHHHHCHHHHHC	33.08	25720772
36	Phosphorylation	QAAKRASSGAFAQLT HHHHHHHCHHHHHCC	32.91	28889911
183	Phosphorylation	AIAGSKDSN------ HHCCCCCCC------	48.45	25720772

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of MLR1_SCHPO !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of MLR1_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of MLR1_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
MYO2_SCHPO	myo2	genetic	11056543
MYO2_SCHPO	myo2	physical	11069761
MYO3_SCHPO	myp2	physical	11069761
MLR4_SCHPO	cdc4	physical	11069761
MYO2_SCHPO	myo2	physical	11056543
MLR4_SCHPO	cdc4	physical	11056543
MYO2_SCHPO	myo2	physical	19570908

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of MLR1_SCHPO

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"Phosphoproteome analysis of fission yeast."; Wilson-Grady J.T., Villen J., Gygi S.P.; J. Proteome Res. 7:1088-1097(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-36, AND MASSSPECTROMETRY.	18257517 [Abstract]