| UniProt ID | CDC45_SCHPO | |
|---|---|---|
| UniProt AC | O74113 | |
| Protein Name | Cell division control protein 45 homolog | |
| Gene Name | sna41 | |
| Organism | Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast). | |
| Sequence Length | 638 | |
| Subcellular Localization | Nucleus . | |
| Protein Description | Required for initiation of chromosomal DNA replication. May have a role in regulating the MCM proteins nda1 and nda4.. | |
| Protein Sequence | MFIKRSDYASAYLKIKEASVSGGCTVQLFVALDPDALCACKLLSTLLKGDFISHKIRPVSGYRDLEQANKTLLEQNEDIKFIILLNCGTMVDLNNYLVSMEDVSIYVIDSHRPHNLNNIYIENNIFVFDDGDIEEDMNKIHDAWYAFNSHELSDEENSDSSNEREEEVEDDNRSVESYSSSDYQARSRRRFSEETTQRRAEIKEKRKKRKEFASILSEYYEKGSWYGESITNILFAVASMLGREDNDMLWLAIVGLTCLEIHCQSSKKYFNRSYSLLKDEVNRLNPSPLENQIVGRAHGKTPHDQSIRLEDEFRFMLVRHWSLYDSMLHSAYVGSRLHIWSEEGRKRLHKLLAKMGLSLVECKQTYIHMNMDLKKTLKSSLKRFAPFYGLDDVIFHSFTRTYGFKCTLSASDVSYAISALLEMGNTGVLLQSKTVARSPDMTEEEYLEKFENAQNQEWLHNFYDAYDALDDVDSLERALKLAMHLQRAIVRTGITLLEKRAIKTLRSFRFGLINEGPDLKIFMHPLALTKMSLWIAEAINEQEREFGKLRHLPLVLAAFVEEKNRYLIVGTSTSAFTSNEDDDDDDGHGHNRFGVAFQEVANMTSATLQMDCFEASVIECQKSDLGVFLESLSFKTLL | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 192 | Phosphorylation | ARSRRRFSEETTQRR HHHHHCCCHHHHHHH | 32.48 | 28889911 | |
| 195 | Phosphorylation | RRRFSEETTQRRAEI HHCCCHHHHHHHHHH | 24.95 | 29996109 | |
| 438 | Phosphorylation | QSKTVARSPDMTEEE EECEECCCCCCCHHH | 18.60 | 28889911 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of CDC45_SCHPO !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of CDC45_SCHPO !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of CDC45_SCHPO !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| MCM2_SCHPO | mcm2 | genetic | 11523776 | |
| RIR1_SCHPO | cdc22 | genetic | 11523776 | |
| RAD4_SCHPO | rad4 | genetic | 11523776 | |
| RAD3_SCHPO | rad3 | genetic | 11523776 | |
| SLD3_SCHPO | sld3 | genetic | 12006645 | |
| HSK1_SCHPO | hsk1 | genetic | 15338237 | |
| MCM10_SCHPO | cdc23 | physical | 12972571 | |
| SLD3_SCHPO | sld3 | physical | 12006645 | |
| MCM3_SCHPO | mcm3 | physical | 15338237 | |
| MCM6_SCHPO | mcm6 | physical | 15338237 | |
| MCM7_SCHPO | mcm7 | physical | 15338237 | |
| MCM7_SCHPO | mcm7 | physical | 15194812 | |
| DPOA_SCHPO | pol1 | physical | 11344166 | |
| MCM6_SCHPO | mcm6 | physical | 11344166 | |
| HSK1_SCHPO | hsk1 | physical | 16990792 | |
| PSF3_SCHPO | psf3 | physical | 16990792 | |
| MCM3_SCHPO | mcm3 | genetic | 15338237 | |
| RAD3_SCHPO | rad3 | genetic | 15338237 | |
| CHK1_SCHPO | chk1 | genetic | 15338237 | |
| MCM2_SCHPO | mcm2 | physical | 22024164 | |
| CHK1_SCHPO | chk1 | genetic | 16849602 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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