dbPTM

CCB12_ARATH - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	CCB12_ARATH
UniProt AC	Q39067
Protein Name	Cyclin-B1-2
Gene Name	CYCB1-2
Organism	Arabidopsis thaliana (Mouse-ear cress).
Sequence Length	445
Subcellular Localization
Protein Description	May induce mitotic cell division..
Protein Sequence	MATRANVPEQVRGAPLVDGLKIQNKNGAVKSRRALGDIGNLVSVPGVQGGKAQPPINRPITRSFRAQLLANAQLERKPINGDNKVPALGPKRQPLAARNPEAQRAVQKKNLVVKQQTKPVEVIETKKEVTKKEVAMSPKNKKVTYSSVLSARSKAACGIVNKPKIIDIDESDKDNHLAAVEYVDDMYSFYKEVEKESQPKMYMHIQTEMNEKMRAILIDWLLEVHIKFELNLETLYLTVNIIDRFLSVKAVPKRELQLVGISALLIASKYEEIWPPQVNDLVYVTDNAYSSRQILVMEKAILGNLEWYLTVPTQYVFLVRFIKASMSDPEMENMVHFLAELGMMHYDTLTFCPSMLAASAVYTARCSLNKSPAWTDTLQFHTGYTESEIMDCSKLLAFLHSRCGESRLRAVYKKYSKAENGGVAMVSPAKSLLSAAADWKKPVSS

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
63	Phosphorylation	INRPITRSFRAQLLA CCCCCCHHHHHHHHH	15.50	29797451
150	Phosphorylation	VTYSSVLSARSKAAC CCHHHHHHHHHHCHH	21.34	25561503

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of CCB12_ARATH !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of CCB12_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of CCB12_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
FZR2_ARATH	FZR2	physical	15970679
FZR1_ARATH	CCS52A2	physical	15970679
FZR3_ARATH	FZR3	physical	15970679
CKB22_ARATH	CDKB2;2	physical	20706207
PSMD6_ARATH	AT4G24820	physical	20706207
CKS2_ARATH	CKS2	physical	20706207
PSD1B_ARATH	AT1G04810	physical	20706207
CISY4_ARATH	ATCS	physical	20706207
IF2B_ARATH	EIF2 BETA	physical	20706207
EIF3B_ARATH	TIF3B1	physical	20706207
NUCL1_ARATH	NUC-L1	physical	20706207

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of CCB12_ARATH

Related Literatures of Post-Translational Modification