ADF1_DROME - dbPTM
ADF1_DROME - PTM Information in dbPTM
Basic Information of Protein
UniProt ID ADF1_DROME
UniProt AC P05552
Protein Name Transcription factor Adf-1
Gene Name Adf1
Organism Drosophila melanogaster (Fruit fly).
Sequence Length 262
Subcellular Localization Nucleus .
Protein Description May play an important role not only in the regulation of Adh expression but also in the transcription of other genes..
Protein Sequence MHTLTAAIEMDKLDANLEQQFDLNLIEAVKLNPVIYDRSHYNYKHFVRKAQTWKQIAETLGVPEQKCTKRWKSLRDKFAREMKLCQESRWRYFKQMQFLVDSIRQYRESLLGKCANGSQSANQVADPSQQQQAQQQTVVDIFAQPFNGSATTSAQALTHPHEITVTSDAQLATAVGKDQKPYFYEPPLKRERSEEEHSDNMLNTIKIFQNNVSQAVSAEDQSFGMVVTDMLNTLGVRQKAEAKVHIIKYLTDMQLLAQHNKY
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
180AcetylationTAVGKDQKPYFYEPP
HHCCCCCCCCCCCCC
52.3921791702
189AcetylationYFYEPPLKRERSEEE
CCCCCCCCCCCCHHH
58.9721791702
193PhosphorylationPPLKRERSEEEHSDN
CCCCCCCCHHHCCCH
44.6119429919

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of ADF1_DROME !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of ADF1_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of ADF1_DROME !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
ADF1_DROMEAdf1physical
14605208
CU059_DROMECG18675physical
14605208
GUS_DROMEgusphysical
14605208
FAS2_DROMEFas2genetic
23864680
STAU_DROMEstaugenetic
23864680
CAD_DROMEcadphysical
23935523
PC_DROMEPcphysical
24668908
HUNB_DROMEhbphysical
23935523
SRP_DROMEsrpphysical
25242320
ADF1_DROMEAdf1physical
23847101

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of ADF1_DROME

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Related Literatures of Post-Translational Modification

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