UniProt ID | ABHDB_HUMAN | |
---|---|---|
UniProt AC | Q8NFV4 | |
Protein Name | Protein ABHD11 {ECO:0000305} | |
Gene Name | ABHD11 {ECO:0000312|HGNC:HGNC:16407} | |
Organism | Homo sapiens (Human). | |
Sequence Length | 315 | |
Subcellular Localization | ||
Protein Description | ||
Protein Sequence | MRAGQQLASMLRWTRAWRLPREGLGPHGPSFARVPVAPSSSSGGRGGAEPRPLPLSYRLLDGEAALPAVVFLHGLFGSKTNFNSIAKILAQQTGRRVLTVDARNHGDSPHSPDMSYEIMSQDLQDLLPQLGLVPCVVVGHSMGGKTAMLLALQRPELVERLIAVDISPVESTGVSHFATYVAAMRAINIADELPRSRARKLADEQLSSVIQDMAVRQHLLTNLVEVDGRFVWRVNLDALTQHLDKILAFPQRQESYLGPTLFLLGGNSQFVHPSHHPEIMRLFPRAQMQTVPNAGHWIHADRPQDFIAAIRGFLV | |
Overview of Protein Modification Sites with Functional and Structural Information | ||
* ASA = Accessible Surface Area
Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
---|---|---|---|---|---|
9 | Phosphorylation | RAGQQLASMLRWTRA CHHHHHHHHHHHHHH | 27.26 | 46157015 | |
39 | Phosphorylation | ARVPVAPSSSSGGRG CCCCCCCCCCCCCCC | 32.87 | 21406692 | |
40 | Phosphorylation | RVPVAPSSSSGGRGG CCCCCCCCCCCCCCC | 27.71 | 21406692 | |
41 | Phosphorylation | VPVAPSSSSGGRGGA CCCCCCCCCCCCCCC | 37.02 | 21406692 | |
42 | Phosphorylation | PVAPSSSSGGRGGAE CCCCCCCCCCCCCCC | 47.41 | 21406692 | |
57 | Phosphorylation | PRPLPLSYRLLDGEA CCCCCCEEEECCCCC | 16.98 | 113327985 | |
80 (in isoform 5) | Ubiquitination | - | 46.90 | 21890473 | |
80 (in isoform 4) | Ubiquitination | - | 46.90 | 21890473 | |
80 | Ubiquitination | HGLFGSKTNFNSIAK HHHHCCCCCHHHHHH | 46.90 | 19608861 | |
80 | Acetylation | HGLFGSKTNFNSIAK HHHHCCCCCHHHHHH | 46.90 | 19608861 | |
80 (in isoform 5) | Acetylation | - | 46.90 | - | |
80 (in isoform 4) | Acetylation | - | 46.90 | - | |
87 (in isoform 3) | Acetylation | - | 36.26 | - | |
87 (in isoform 2) | Acetylation | - | 36.26 | - | |
87 | Succinylation | TNFNSIAKILAQQTG CCHHHHHHHHHHHHC | 36.26 | 19608861 | |
87 | Ubiquitination | TNFNSIAKILAQQTG CCHHHHHHHHHHHHC | 36.26 | 21890473 | |
87 (in isoform 1) | Ubiquitination | - | 36.26 | 21890473 | |
87 (in isoform 2) | Ubiquitination | - | 36.26 | 21890473 | |
87 (in isoform 3) | Ubiquitination | - | 36.26 | 21890473 | |
87 | Succinylation | TNFNSIAKILAQQTG CCHHHHHHHHHHHHC | 36.26 | - | |
87 | Acetylation | TNFNSIAKILAQQTG CCHHHHHHHHHHHHC | 36.26 | 19608861 | |
193 (in isoform 4) | Ubiquitination | - | 4.37 | 21890473 | |
196 | Phosphorylation | IADELPRSRARKLAD HHHHCCHHHHHHHHH | 28.49 | 24825855 | |
200 | Ubiquitination | LPRSRARKLADEQLS CCHHHHHHHHHHHHH | 47.22 | 2190698 | |
200 (in isoform 1) | Ubiquitination | - | 47.22 | 21890473 | |
221 | Phosphorylation | AVRQHLLTNLVEVDG HHHHHHHHHHEEECC | 32.63 | 68730483 |
Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of ABHDB_HUMAN !! |
Modified Location | Modified Residue | Modification | Function | Reference | ||
---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of ABHDB_HUMAN !! |
* Distance = the distance between SAP position and PTM sites.
Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of ABHDB_HUMAN !! |
Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
---|---|---|---|---|
A4_HUMAN | APP | physical | 21832049 | |
PGM1_HUMAN | PGM1 | physical | 26344197 | |
NDKM_HUMAN | NME4 | physical | 27499296 | |
ABHDB_HUMAN | ABHD11 | physical | 27499296 | |
BOLA3_HUMAN | BOLA3 | physical | 27499296 | |
DHRS4_HUMAN | DHRS4 | physical | 27499296 | |
HOGA1_HUMAN | HOGA1 | physical | 27499296 | |
BOLA1_HUMAN | BOLA1 | physical | 27499296 | |
ACAD8_HUMAN | ACAD8 | physical | 27499296 | |
ECH1_HUMAN | ECH1 | physical | 27499296 | |
MIA40_HUMAN | CHCHD4 | physical | 27499296 | |
C1QBP_HUMAN | C1QBP | physical | 27499296 |
Kegg Disease | ||||||
---|---|---|---|---|---|---|
There are no disease associations of PTM sites. | ||||||
OMIM Disease | ||||||
There are no disease associations of PTM sites. | ||||||
Kegg Drug | ||||||
There are no disease associations of PTM sites. | ||||||
DrugBank | ||||||
There are no disease associations of PTM sites. |
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Acetylation | |
Reference | PubMed |
"Lysine acetylation targets protein complexes and co-regulates majorcellular functions."; Choudhary C., Kumar C., Gnad F., Nielsen M.L., Rehman M., Walther T.,Olsen J.V., Mann M.; Science 325:834-840(2009). Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-87, AND MASS SPECTROMETRY. |