ZN488_HUMAN - dbPTM
ZN488_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID ZN488_HUMAN
UniProt AC Q96MN9
Protein Name Zinc finger protein 488
Gene Name ZNF488
Organism Homo sapiens (Human).
Sequence Length 340
Subcellular Localization Nucleus .
Protein Description May be involved in transcriptional regulation..
Protein Sequence MPEWPPCLSVAPALVITMAAGKGAPLSPSAENRWRLSEPELGRGCKPVLLEKTNRLGPEAAVGRAGRDVGSAELALLVAPGKPRPGKPLPPKTRGEQRQSAFTELPRMKDRQVDAQAQEREHDDPTGQPGAPQLTQNIPRGPAGSKVFSVWPSGARSEQRSAFSKPTKRPAERPELTSVFPAGESADALGELSGLLNTTDLACWGRLSTPKLLVGDLWNLQALPQNAPLCSTFLGAPTLWLEHTQAQVPPPSSSSTTSWALLPPTLTSLGLSTQNWCAKCNLSFRLTSDLVFHMRSHHKKEHAGPDPHSQKRREEALACPVCQEHFRERHHLSRHMTSHS
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
27PhosphorylationAGKGAPLSPSAENRW
CCCCCCCCCCCCCCC
18.7527794612
29PhosphorylationKGAPLSPSAENRWRL
CCCCCCCCCCCCCCC
44.8527794612
64MethylationGPEAAVGRAGRDVGS
CHHHHCCCCCCCCCC
27.54115920501
103PhosphorylationEQRQSAFTELPRMKD
HHHHHHHHHCCHHHH
36.01-
157PhosphorylationVWPSGARSEQRSAFS
ECCCCCCHHHHHCCC
37.23-
283PhosphorylationWCAKCNLSFRLTSDL
CHHHCCCEEEECHHH
8.3724719451

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of ZN488_HUMAN !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of ZN488_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of ZN488_HUMAN !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
PR20E_HUMANPRR20Aphysical
25416956
PR20C_HUMANPRR20Aphysical
25416956
PR20D_HUMANPRR20Aphysical
25416956
PR20B_HUMANPRR20Aphysical
25416956
PR20A_HUMANPRR20Aphysical
25416956
K1C40_HUMANKRT40physical
25416956
USO1_HUMANUSO1physical
28514442
CGL_HUMANCTHphysical
28514442
GOPC_HUMANGOPCphysical
28514442
HSP7C_HUMANHSPA8physical
28514442
KCC2G_HUMANCAMK2Gphysical
28514442

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of ZN488_HUMAN

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Related Literatures of Post-Translational Modification

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