ZN202_HUMAN - dbPTM
ZN202_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID ZN202_HUMAN
UniProt AC O95125
Protein Name Zinc finger protein 202
Gene Name ZNF202
Organism Homo sapiens (Human).
Sequence Length 648
Subcellular Localization Nucleus.
Protein Description Transcriptional repressor that binds to elements found predominantly in genes that participate in lipid metabolism. Among its targets are structural components of lipoprotein particles (apolipoproteins AIV, CIII, and E), enzymes involved in lipid processing (lipoprotein lipase, lecithin cholesteryl ester transferase), transporters involved in lipid homeostasis (ABCA1, ABCG1), and several genes involved in processes related to energy metabolism and vascular disease..
Protein Sequence MATAVEPEDQDLWEEEGILMVKLEDDFTCRPESVLQRDDPVLETSHQNFRRFRYQEAASPREALIRLRELCHQWLRPERRTKEQILELLVLEQFLTVLPGELQSWVRGQRPESGEEAVTLVEGLQKQPRRPRRWVTVHVHGQEVLSEETVHLGVEPESPNELQDPVQSSTPEQSPEETTQSPDLGAPAEQRPHQEEELQTLQESEVPVPEDPDLPAERSSGDSEMVALLTALSQGLVTFKDVAVCFSQDQWSDLDPTQKEFYGEYVLEEDCGIVVSLSFPIPRPDEISQVREEEPWVPDIQEPQETQEPEILSFTYTGDRSKDEEECLEQEDLSLEDIHRPVLGEPEIHQTPDWEIVFEDNPGRLNERRFGTNISQVNSFVNLRETTPVHPLLGRHHDCSVCGKSFTCNSHLVRHLRTHTGEKPYKCMECGKSYTRSSHLARHQKVHKMNAPYKYPLNRKNLEETSPVTQAERTPSVEKPYRCDDCGKHFRWTSDLVRHQRTHTGEKPFFCTICGKSFSQKSVLTTHQRIHLGGKPYLCGECGEDFSEHRRYLAHRKTHAAEELYLCSECGRCFTHSAAFAKHLRGHASVRPCRCNECGKSFSRRDHLVRHQRTHTGEKPFTCPTCGKSFSRGYHLIRHQRTHSEKTS
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
3Phosphorylation-----MATAVEPEDQ
-----CCCCCCCCCC		29.91-
22SumoylationEEGILMVKLEDDFTC
HCCEEEEEECCCCCC		31.9928112733
28PhosphorylationVKLEDDFTCRPESVL
EEECCCCCCCHHHHH		18.0130266825
33PhosphorylationDFTCRPESVLQRDDP
CCCCCHHHHHCCCCC		30.7030266825
44PhosphorylationRDDPVLETSHQNFRR
CCCCCCCCHHHHHHH		27.6121406692
45PhosphorylationDDPVLETSHQNFRRF
CCCCCCCHHHHHHHH		17.4421406692
379PhosphorylationTNISQVNSFVNLRET
CCHHHCHHCCCCCCC		31.54-
386PhosphorylationSFVNLRETTPVHPLL
HCCCCCCCCCCCCCC		29.9323312004
387PhosphorylationFVNLRETTPVHPLLG
CCCCCCCCCCCCCCC		20.6823312004
418PhosphorylationHLVRHLRTHTGEKPY
HHHHHHHHCCCCCCE		30.1028348404
420PhosphorylationVRHLRTHTGEKPYKC
HHHHHHCCCCCCEEE		46.5626270265
423UbiquitinationLRTHTGEKPYKCMEC
HHHCCCCCCEEEECC		55.80-
454SumoylationHKMNAPYKYPLNRKN
HHCCCCCCCCCCCCC		39.0628112733
460SumoylationYKYPLNRKNLEETSP
CCCCCCCCCCCCCCC		65.8828112733
465PhosphorylationNRKNLEETSPVTQAE
CCCCCCCCCCCCCCC		29.0228450419
466PhosphorylationRKNLEETSPVTQAER
CCCCCCCCCCCCCCC		22.209790754
469PhosphorylationLEETSPVTQAERTPS
CCCCCCCCCCCCCCC		25.9930108239
474PhosphorylationPVTQAERTPSVEKPY
CCCCCCCCCCCCCCE		16.0625627689
476PhosphorylationTQAERTPSVEKPYRC
CCCCCCCCCCCCEEC		42.1525627689
481PhosphorylationTPSVEKPYRCDDCGK
CCCCCCCEECCCCCC		34.6326657352
493PhosphorylationCGKHFRWTSDLVRHQ
CCCCCCCHHHHHHCC		14.2226657352
494PhosphorylationGKHFRWTSDLVRHQR
CCCCCCHHHHHHCCC		23.2226657352
502PhosphorylationDLVRHQRTHTGEKPF
HHHHCCCCCCCCCCE		19.74-
504PhosphorylationVRHQRTHTGEKPFFC
HHCCCCCCCCCCEEE		46.56-
507SumoylationQRTHTGEKPFFCTIC
CCCCCCCCCEEEEEC		48.7728112733
521SumoylationCGKSFSQKSVLTTHQ
CCCCCCCCCCEEECC		41.1428112733
577PhosphorylationCGRCFTHSAAFAKHL
CCCCCHHHHHHHHHH		20.4526437602
603PhosphorylationNECGKSFSRRDHLVR
CCCCCCCCCHHHHHH		33.2317081983
614PhosphorylationHLVRHQRTHTGEKPF
HHHHHCCCCCCCCCC		19.74-
616PhosphorylationVRHQRTHTGEKPFTC
HHHCCCCCCCCCCCC		46.56-
631PhosphorylationPTCGKSFSRGYHLIR
CCCCCCCHHCHHHHH		31.7017081983
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of ZN202_HUMAN !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of ZN202_HUMAN !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of ZN202_HUMAN !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
ZN473_HUMANZNF473physical
16189514
K1C40_HUMANKRT40physical
25416956
KR103_HUMANKRTAP10-3physical
25416956
ZMYM2_HUMANZMYM2physical
28514442
ZMYM3_HUMANZMYM3physical
28514442
SCND1_HUMANSCAND1physical
28514442
KITH_HUMANTK1physical
28514442
RCOR3_HUMANRCOR3physical
28514442
Drug and Disease Associations
Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of ZN202_HUMAN

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Related Literatures of Post-Translational Modification

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