ZBT25_HUMAN - dbPTM
ZBT25_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID ZBT25_HUMAN
UniProt AC P24278
Protein Name Zinc finger and BTB domain-containing protein 25
Gene Name ZBTB25
Organism Homo sapiens (Human).
Sequence Length 435
Subcellular Localization Nucleus.
Protein Description May be involved in transcriptional regulation..
Protein Sequence MDTASHSLVLLQQLNMQREFGFLCDCTVAIGDVYFKAHRAVLAAFSNYFKMIFIHQTSECIKIQPTDIQPDIFSYLLHIMYTGKGPKQIVDHSRLEEGIRFLHADYLSHIATEMNQVFSPETVQSSNLYGIQISTTQKTVVKQGLEVKEAPSSNSGNRAAVQGDHPQLQLSLAIGLDDGTADQQRACPATQALEEHQKPPVSIKQERCDPESVISQSHPSPSSEVTGPTFTENSVKIHLCHYCGERFDSRSNLRQHLHTHVSGSLPFGVPASILESNDLGEVHPLNENSEALECRRLSSFIVKENEQQPDHTNRGTTEPLQISQVSLISKDTEPVELNCNFSFSRKRKMSCTICGHKFPRKSQLLEHMYTHKGKSYRYNRCQRFGNALAQRFQPYCDSWSDVSLKSSRLSQEHLDLPCALESELTQENVDTILVE
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
3Phosphorylation-----MDTASHSLVL
-----CCHHHHHHHH		28.8524043423
5Phosphorylation---MDTASHSLVLLQ
---CCHHHHHHHHHH		18.7224043423
7Phosphorylation-MDTASHSLVLLQQL
-CCHHHHHHHHHHHH		20.0624043423
142SumoylationTTQKTVVKQGLEVKE
CCCCCHHHCCEEEEE		34.02-
142UbiquitinationTTQKTVVKQGLEVKE
CCCCCHHHCCEEEEE		34.02-
142SumoylationTTQKTVVKQGLEVKE
CCCCCHHHCCEEEEE		34.0228112733
148UbiquitinationVKQGLEVKEAPSSNS
HHCCEEEEECCCCCC		38.4921906983
148SumoylationVKQGLEVKEAPSSNS
HHCCEEEEECCCCCC		38.4928112733
198SumoylationQALEEHQKPPVSIKQ
HHHHHHCCCCCCCCC		53.8728112733
204SumoylationQKPPVSIKQERCDPE
CCCCCCCCCCCCCHH		38.3028112733
212PhosphorylationQERCDPESVISQSHP
CCCCCHHHHHCCCCC		30.0923312004
215PhosphorylationCDPESVISQSHPSPS
CCHHHHHCCCCCCCC		24.3930108239
217PhosphorylationPESVISQSHPSPSSE
HHHHHCCCCCCCCCC		30.4930108239
220PhosphorylationVISQSHPSPSSEVTG
HHCCCCCCCCCCCCC		31.8028450419
222PhosphorylationSQSHPSPSSEVTGPT
CCCCCCCCCCCCCCC		43.3928450419
223PhosphorylationQSHPSPSSEVTGPTF
CCCCCCCCCCCCCCC		39.2028450419
226PhosphorylationPSPSSEVTGPTFTEN
CCCCCCCCCCCCCCC		33.1330108239
229PhosphorylationSSEVTGPTFTENSVK
CCCCCCCCCCCCCEE		44.5330108239
231PhosphorylationEVTGPTFTENSVKIH
CCCCCCCCCCCEEEE		36.4130108239
234PhosphorylationGPTFTENSVKIHLCH
CCCCCCCCEEEEECC		20.6830108239
249PhosphorylationYCGERFDSRSNLRQH
CCCCCCCCCCCHHHH		34.59-
251PhosphorylationGERFDSRSNLRQHLH
CCCCCCCCCHHHHHH		44.14-
298PhosphorylationALECRRLSSFIVKEN
HHHHHHHHHEEEECC		22.7627251275
299PhosphorylationLECRRLSSFIVKENE
HHHHHHHHEEEECCC		24.4728348404
303UbiquitinationRLSSFIVKENEQQPD
HHHHEEEECCCCCCC		50.43-
303SumoylationRLSSFIVKENEQQPD
HHHHEEEECCCCCCC		50.4328112733
326PhosphorylationPLQISQVSLISKDTE
CEEEEEEEEECCCCC		16.6124719451
330SumoylationSQVSLISKDTEPVEL
EEEEEECCCCCCEEE		62.7728112733
342PhosphorylationVELNCNFSFSRKRKM
EEEECEEEECCCCCC		14.3425159151
350PhosphorylationFSRKRKMSCTICGHK
ECCCCCCEEEECCCC		15.90-
362PhosphorylationGHKFPRKSQLLEHMY
CCCCCCHHHHHHHHH		27.6028555341
370PhosphorylationQLLEHMYTHKGKSYR
HHHHHHHHCCCCCHH		14.9928555341
372UbiquitinationLEHMYTHKGKSYRYN
HHHHHHCCCCCHHHC		61.30-
374UbiquitinationHMYTHKGKSYRYNRC
HHHHCCCCCHHHCHH		49.47-
405UbiquitinationSWSDVSLKSSRLSQE
CHHHCCHHHCCCCHH		38.59-
405SumoylationSWSDVSLKSSRLSQE
CHHHCCHHHCCCCHH		38.5928112733
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of ZBT25_HUMAN !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of ZBT25_HUMAN !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of ZBT25_HUMAN !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
KXDL1_HUMANKXD1physical
16189514
VINEX_HUMANSORBS3physical
16189514
ZBT25_HUMANZBTB25physical
20211142
SSX3_HUMANSSX3physical
20211142
ZBTB1_HUMANZBTB1physical
20211142
ZBT25_HUMANZBTB25physical
25416956
TNIP1_HUMANTNIP1physical
25416956
SPS1_HUMANSEPHS1physical
25416956
MTNB_HUMANAPIPphysical
25416956
TSSK3_HUMANTSSK3physical
25416956
LZTS2_HUMANLZTS2physical
25416956
PNMA5_HUMANPNMA5physical
25416956
KCTD1_HUMANKCTD1physical
25416956
Drug and Disease Associations
Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of ZBT25_HUMAN

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Related Literatures of Post-Translational Modification

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