YRF15_YEAST - dbPTM
YRF15_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID YRF15_YEAST
UniProt AC P0CX21
Protein Name Y' element ATP-dependent helicase protein 1 copy 5
Gene Name YRF1-5
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 1796
Subcellular Localization
Protein Description Catalyzes DNA unwinding and is involved in telomerase-independent telomere maintenance..
Protein Sequence MKVSDRRKFEKANFDEFESALNNKNDLVHCPSITLFESIPTEVRSFYEDEKSGLIKVVKFRTGAMDRKRSFEKIVISVMVGKNVQKFLTFVEDEPDFQGGPIPSKYLIPKKINLMVYTLFQVHTLKFNRKDYDTLSLFYLNRGYYNELSFRVLERCHEIASARPNDSSTMRTFTDFVSGAPIVRSLQKSTIRKYGYNLAPYMFLLLHVDELSIFSAYQASLPGEKKVDTERLKRDLCPRKPIEIKYFSQICNDMMNKKDRLGDILHIILRACALNFGAGPRGGAGDEEDRSITNEEPIIPSVDEHGLKVCKLRSPNTPRRLRKTLDAVKALLVSSCACTARDLDIFDDTNGVAMWKWIKILYHEVAQETTLKDSYRITLVPSSDGISVCGKLFNREYVRGFYFACKAQFDNLWGELNNCFYMPTVVDIASLILRNREVLFREPKRGIDEYLENDSFLQMIPVKYREIVLPKLRRDTNKMTAALKNKVTVAIDELTVPLMWMVHFAVGYPYRYPELQLLAFAGPQRNVYVDDTTRRIQLYTDYNKNGSSEPRLKTLDGLTSDYVFYFVTVLRQMQICALGNSYDAFNHDPWMDVVGFEDPDQVTNRDISRIVLYSYMFLNTAKGCLVEYATFRQYMRELPKNAPQKLNFREMRQGLIALGRHCVGSRFETDLYESATSELMANHSVQTGRNIYGVDSFSLTSVSGTTATLLQERASERWIQWLGLESDYHCSFSSTRNAEDVVAGEAASSDHDQKISRVTRKRPREPKSTNDILVAGQKLFGSSFEFRDLHQLRLCHEIYMADTPSVAVQAPPGYGKTELFHLPLIALASKGDVKYVSFLFVPYTVLLANCMIRLSRCGCLNVAPVRNFIEEGCDGVTDLYVGIYDDLASTNFTDRIAAWENIVECTFRTNNVKLGYLIVDEFHNFETEVYRQSQFGGITNLDFDAFEKAIFLSGTAPEAVADAALQRIGLTGLAKKSMDINELKRSEDLSRGLSSYPTRMFNLIKEKSEVPLGHVHKIWKKVESQPEEALKLLLALFEIEPESKAIVVASTTNEVEELACSWRKYFRVVWIHGKLGAAEKVSRTKEFVTDGSMRVLIGTKLVTEGIDIKQLMMVIMLDNRLNIIELIQGVGRLRDGGLCYLLSRKNSWAARNRKGELPPIKEGCITEQVREFYGLESKKGKKGQHVGCCGSRTDLSADTVELIERMDRLAEKQATASMSIIALPSSFQESNSSDRCRKYCSSDEDSDTCIHGSANASTNATTNSSTNATTTASTNVRTSATTTASINVRTSAITTESTNSSTNATTTASTNVRTSATTTASINVRTSATTTESTNSNTSATTTESTDSNTSATTTESTDSNTSATTTASTNSSTNATTTASTNSSTNATTTESTNASAKEDANKDGNAEDNRFHPVTDINKESYKRKGSQMVLLERKKLKAQFPNTSENMNVLQFLGFRSDEIKHLFLYGIDVYFCPEGVFTQYGLCKGCQKMFELCVCWAGQKVSYRRMAWEALAVERMLRNDEEYKEYLEDIEPYHGDPVGYLKYFSVKRGEIYSQIQRNYAWYLAITRRRETISVLDSTRGKQGSQVFRMSGRQIKELYYKVWSNLRESKTEVLQYFLNWDEKKCREEWEAKDDTVFVEALEKVGVFQRLRSMTSAGLQGPQYVKLQFSRHHRQLRSRYELSLGMHLRDQLALGVTPSKVPHWTAFLSMLIGLFYNKTFRQKLEYLLEQISEVWLLPHWLDLANVEVLAADNTRVPLYMLMVAVHKELDSDDVPDGRFDIILLCRDSSREVGE
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
291PhosphorylationAGDEEDRSITNEEPI
CCCHHHCCCCCCCCC		46.1919779198
362PhosphorylationWKWIKILYHEVAQET
HHHHHHHHHHHHHHC		10.2127017623
696PhosphorylationRNIYGVDSFSLTSVS
CCEECCCCCEEEECC		17.8327214570
703PhosphorylationSFSLTSVSGTTATLL
CCEEEECCCCHHHHH		30.1427214570
748PhosphorylationVVAGEAASSDHDQKI
HHHHHHCCCCHHHHH		43.2622369663
749PhosphorylationVAGEAASSDHDQKIS
HHHHHCCCCHHHHHH		33.9522369663
756PhosphorylationSDHDQKISRVTRKRP
CCHHHHHHHHHCCCC		27.9521082442
1147PhosphorylationYLLSRKNSWAARNRK
EEEECCCCHHHHCCC		22.5627214570
1215PhosphorylationRLAEKQATASMSIIA
HHHHHHHHHCEEEEE		19.4419684113
1217PhosphorylationAEKQATASMSIIALP
HHHHHHHCEEEEECC		14.5428889911
1226PhosphorylationSIIALPSSFQESNSS
EEEECCCCCCCCCCC		29.0728889911
1230PhosphorylationLPSSFQESNSSDRCR
CCCCCCCCCCCHHHH		31.0919779198
1232PhosphorylationSSFQESNSSDRCRKY
CCCCCCCCCHHHHHH		42.7819779198
1233PhosphorylationSFQESNSSDRCRKYC
CCCCCCCCHHHHHHC		33.0719684113
1273PhosphorylationTNATTTASTNVRTSA
CCCEECCCCEECCCC		20.5828889911
1278PhosphorylationTASTNVRTSATTTAS
CCCCEECCCCEEEEE		20.5927017623
1283PhosphorylationVRTSATTTASINVRT
ECCCCEEEEEEEEEE		17.6627017623
1309PhosphorylationTNATTTASTNVRTSA
CCCEEEEECCEECCE		20.5828889911
1314PhosphorylationTASTNVRTSATTTAS
EEECCEECCEEEEEE		20.5927017623
1319PhosphorylationVRTSATTTASINVRT
EECCEEEEEEEEEEE		17.6627017623
1389PhosphorylationTNSSTNATTTESTNA
CCCCCCCCCCCCCCC		36.0027017623
1391PhosphorylationSSTNATTTESTNASA
CCCCCCCCCCCCCHH		24.4727017623
1394PhosphorylationNATTTESTNASAKED
CCCCCCCCCCHHCHH		28.6827017623
1429PhosphorylationESYKRKGSQMVLLER
HHHHCCCCEEEEEEH		20.3825752575
1655PhosphorylationGVFQRLRSMTSAGLQ
CHHHHHHHCCCCCCC		30.8827017623
1666PhosphorylationAGLQGPQYVKLQFSR
CCCCCCCEEEEEECH		11.5927017623
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of YRF15_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of YRF15_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of YRF15_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
HAP3_YEASTHAP3genetic
27708008
MTU1_YEASTSLM3genetic
27708008
GCS1_YEASTGCS1genetic
27708008
COX23_YEASTCOX23genetic
27708008
HAP4_YEASTHAP4genetic
27708008
COXM1_YEASTCMC1genetic
27708008
COX12_YEASTCOX12genetic
27708008
CY1_YEASTCYT1genetic
27708008
MNE1_YEASTMNE1genetic
27708008
YME1_YEASTYME1genetic
27708008
MSS18_YEASTMSS18genetic
27708008
QCR2_YEASTQCR2genetic
27708008
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of YRF15_YEAST

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Related Literatures of Post-Translational Modification

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