| UniProt ID | VPS36_ARATH | |
|---|---|---|
| UniProt AC | Q9FF81 | |
| Protein Name | Vacuolar protein sorting-associated protein 36 | |
| Gene Name | VPS36 | |
| Organism | Arabidopsis thaliana (Mouse-ear cress). | |
| Sequence Length | 440 | |
| Subcellular Localization | Endosome. | |
| Protein Description | Component of the ESCRT-II complex (endosomal sorting complex required for transport II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. The ESCRT-II complex is probably involved in the recruitment of the ESCRT-III complex (By similarity).. | |
| Protein Sequence | MASGSSSIAIGGLFENAEVTTSGRPVLRRNEVECFLLSSIDIDSEDDPPRFTALRSGNLILTTHRLIWIPSQSNESVPSSIPLSAVTHIYSHKKSIKSMFHSPRIRFQADPGSIVVTIVFRGKGDFDGFLSKLWECWRGRAWEEEEKSESETSKSGSGTVAQGLYGNDGTVRMVGLAGILRKEQEQWESTDKSLQDAFQDLNALMSKAKEMVSLAEKMRQKLLSAPSSQNGSTDDEEMGSKEEMQQWMLSVGIISPVTKESAGALYHQELSRQLADFVRIPLEKAGGMISLTDMYYHFNRARGTELISPDDLWQACTLWEKFDVPVMLRKFDSGVMVIQNKSHSDEEVMSRIRMLVTKTETLRVGVTASDAALTLKIAPAMAKEHLLSAETKGLLCRDMSPDGLRFYFNLFPEIDPTNLHIVKEFGTYGEWIKATSLLSV | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 148 | Phosphorylation | AWEEEEKSESETSKS CHHHHHHCCCCCCCC | 50.03 | 23111157 | |
| 150 | Phosphorylation | EEEEKSESETSKSGS HHHHHCCCCCCCCCC | 53.95 | 30407730 | |
| 152 | Phosphorylation | EEKSESETSKSGSGT HHHCCCCCCCCCCCC | 51.22 | 27545962 | |
| 213 | Phosphorylation | SKAKEMVSLAEKMRQ HHHHHHHHHHHHHHH | 22.13 | 24894044 | |
| 333 | Phosphorylation | VMLRKFDSGVMVIQN EEEEECCCCEEEEEC | 36.10 | 23820729 | |
| 357 | Phosphorylation | SRIRMLVTKTETLRV HHHHHHHCCCCEEEC | 28.43 | 23820729 | |
| 359 | Phosphorylation | IRMLVTKTETLRVGV HHHHHCCCCEEECCC | 25.49 | 23820729 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of VPS36_ARATH !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of VPS36_ARATH !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of VPS36_ARATH !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| ELC_ARATH | ELC | physical | 21442383 | |
| ELCL_ARATH | ELC-Like | physical | 21442383 | |
| VP201_ARATH | VPS20.1 | physical | 21442383 | |
| VP202_ARATH | VPS20.2 | physical | 21442383 | |
| VPS36_ARATH | AT5G04920 | physical | 21442383 | |
| VPS2A_ARATH | VPS2.1 | physical | 21442383 | |
| ELC_ARATH | ELC | physical | 22639582 | |
| ELCL_ARATH | ELC-Like | physical | 22639582 | |
| VP221_ARATH | VPS22 | physical | 22639582 | |
| VPS36_ARATH | AT5G04920 | physical | 22639582 | |
| VP202_ARATH | VPS20.2 | physical | 22639582 | |
| VP201_ARATH | VPS20.1 | physical | 22639582 | |
| VPS25_ARATH | VPS25 | physical | 22639582 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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